Gene name: ZWF1
Reference locus (S288C): YNL241C
Gene biotype: protein_coding
Description: Glucose-6-phosphate dehydrogenase (G6PD); catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidative stress; protein abundance increases in response to DNA replication stress; homolog of human G6PD which is deficient in patients with hemolytic anemia; human G6PD can complement yeast zwf1 null mutant
Top 10 interactors (score): GND2 (0.999); GND1 (0.999); RPE1 (0.998); SOL4 (0.998); PGI1 (0.998); SOL1 (0.997); SOL3 (0.997); SOL2 (0.997); TAL1 (0.991); TKL1 (0.989); POS5 (0.986); TDH3 (0.983); TDH1 (0.983); YLR446W (0.981); TPI1 (0.978); TDH2 (0.977); CDC19 (0.976); PYK2 (0.976); GLK1 (0.973); PGM2 (0.972)
Homologues (species, bitscore): G6PD (Homo sapiens, 451.8); G6pdx (Mus musculus, 458.0); g6pd (Danio rerio, 460.7); G6PD (Xenopus tropicalis, 387.5); Zw (Drosophila melanogaster, 469.2); gspd-1 (Caenorhabditis elegans, 467.2); G6PD6 (Arabidopsis thaliana, 486.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:190211-191725:- | gene-YNL241C_AKU4011 | rna-NM_001183079.1_AKU4011 | cds-NP_014158.1_AKU4011 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:94151-95665:- | gene-YNL241C_BG1 | rna-NM_001183079.1_BG1 | cds-NP_014158.1_BG1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:200013-201527:- | gene-YNL241C_Bruggeman | rna-NM_001183079.1_Bruggeman | cds-NP_014158.1_Bruggeman | 99.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:207310-208824:- | gene-YNL241C_CAT1 | rna-NM_001183079.1_CAT1 | cds-NP_014158.1_CAT1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:190608-192122:- | gene-YNL241C_CBS1585 | rna-NM_001183079.1_CBS1585 | cds-NP_014158.1_CBS1585 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:185693-187207:- | gene-YNL241C_CBS436 | rna-NM_001183079.1_CBS436 | cds-NP_014158.1_CBS436 | 99.8 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:186647-188161:- | gene-YNL241C_CBS6412 | rna-NM_001183079.1_CBS6412 | cds-NP_014158.1_CBS6412 | 99.1 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:187290-188804:- | gene-YNL241C_CBS6413 | rna-NM_001183079.1_CBS6413 | cds-NP_014158.1_CBS6413 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:190237-191754:- | gene-YNL241C_CENPK1137D | rna-NM_001183079.1_CENPK1137D | cds-NP_014158.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:187867-189381:- | gene-YNL241C_EthanolRed | rna-NM_001183079.1_EthanolRed | cds-NP_014158.1_EthanolRed | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:182602-184116:- | gene-YNL241C_FaliES1 | rna-NM_001183079.1_FaliES1 | cds-NP_014158.1_FaliES1 | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:93744-95258:- | gene-YNL241C_JAY291 | rna-NM_001183079.1_JAY291 | cds-NP_014158.1_JAY291 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:195796-197310:- | gene-YNL241C_MUCL30387 | rna-NM_001183079.1_MUCL30387 | cds-NP_014158.1_MUCL30387 | 99.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:194381-195895:- | gene-YNL241C_MUCL30388 | rna-NM_001183079.1_MUCL30388 | cds-NP_014158.1_MUCL30388 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:188098-189612:- | gene-YNL241C_MUCL39482 | rna-NM_001183079.1_MUCL39482 | cds-NP_014158.1_MUCL39482 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:190353-191867:- | gene-YNL241C_MUCL42920 | rna-NM_001183079.1_MUCL42920 | cds-NP_014158.1_MUCL42920 | 99.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:196395-197912:- | gene-YNL241C_NCIM3186 | rna-NM_001183079.1_NCIM3186 | cds-NP_014158.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:190186-191700:- | gene-YNL241C_NCYC1407 | rna-NM_001183079.1_NCYC1407 | cds-NP_014158.1_NCYC1407 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:187087-188601:- | gene-YNL241C_PE2H3 | rna-NM_001183079.1_PE2H3 | cds-NP_014158.1_PE2H3 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:186475-187989:- | gene-YNL241C_PE2H4 | rna-NM_001183079.1_PE2H4 | cds-NP_014158.1_PE2H4 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:196426-197943:- | gene-YNL241C_S288C | rna-NM_001183079.1_S288C | cds-NP_014158.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:54357-55871:+ | gene-YNL241C_SA1 | rna-NM_001183079.1_SA1 | cds-NP_014158.1_SA1 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:183458-184972:- | gene-YNL241C_ThermosaccDry | rna-NM_001183079.1_ThermosaccDry | cds-NP_014158.1_ThermosaccDry | 99.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:202343-203857:- | gene-YNL241C_VR1 | rna-NM_001183079.1_VR1 | cds-NP_014158.1_VR1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:93778-95292:- | gene-YNL241C_ZTW1 | rna-NM_001183079.1_ZTW1 | cds-NP_014158.1_ZTW1 | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:193710-195224:- | gene-YNL241C_Sparadoxus | rna-NM_001183079.1_Sparadoxus | cds-NP_014158.1_Sparadoxus | 92.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |