Gene name: ZRC1
Reference locus (S288C): YMR243C
Gene biotype: protein_coding
Description: Solute carrier family 30 (zinc transporter), member 1; Zinc/cadmium resistance protein; Vacuolar membrane zinc transporter; transports zinc from cytosol to vacuole for storage; also has role in resistance to zinc shock resulting from sudden influx of zinc into cytoplasm; human ortholog SLC30A10 functions as a Mn transporter and mutations in SLC30A10 cause neurotoxic accumulation of Mn in liver and brain; ZRC1 has a paralog, COT1, that arose from the whole genome duplication
Top 10 interactors (score): COT1 (0.999); YKE4 (0.977); ZRT3 (0.967); ZRG17 (0.965); ZRT1 (0.96); ZRT2 (0.958); ZAP1 (0.898); FET4 (0.888); PDR18 (0.84); SMF1 (0.804); ATX2 (0.802); YCF1 (0.777); CCC1 (0.731); FET3 (0.717); ZPS1 (0.691); PDR10 (0.683); CCC2 (0.665); YOL075C (0.663); SMF3 (0.656); YBR287W (0.656)
Homologues (species, bitscore): SLC30A1 (Homo sapiens, 252.3); Slc30a1 (Mus musculus, 247.7); slc30a1b (Danio rerio, 274.2); slc30a10 (Xenopus tropicalis, 248.4); ZnT63C (Drosophila melanogaster, 287.7); cdf-1 (Caenorhabditis elegans, 177.9); AT2G04620 (Arabidopsis thaliana, 175.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:794743-796071:- | gene-YMR243C_AKU4011 | rna-NM_001182750.1_AKU4011 | cds-NP_013970.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:158520-159848:+ | gene-YMR243C_BG1 | rna-NM_001182750.1_BG1 | cds-NP_013970.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:738968-740296:- | gene-YMR243C_Bruggeman | rna-NM_001182750.1_Bruggeman | cds-NP_013970.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:742863-744191:- | gene-YMR243C_CAT1 | rna-NM_001182750.1_CAT1 | cds-NP_013970.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:727002-728330:- | gene-YMR243C_CBS1585 | rna-NM_001182750.1_CBS1585 | cds-NP_013970.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:731270-732598:- | gene-YMR243C_CBS436 | rna-NM_001182750.1_CBS436 | cds-NP_013970.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:838563-839891:- | gene-YMR243C_CBS6412 | rna-NM_001182750.1_CBS6412 | cds-NP_013970.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:726154-727482:- | gene-YMR243C_CBS6413 | rna-NM_001182750.1_CBS6413 | cds-NP_013970.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:749581-750909:- | gene-YMR243C_CENPK1137D | rna-NM_001182750.1_CENPK1137D | cds-NP_013970.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:787403-788731:- | gene-YMR243C_EthanolRed | rna-NM_001182750.1_EthanolRed | cds-NP_013970.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:733427-734755:- | gene-YMR243C_FaliES1 | rna-NM_001182750.1_FaliES1 | cds-NP_013970.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:51829-53157:+ | gene-YMR243C_JAY291 | rna-NM_001182750.1_JAY291 | cds-NP_013970.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:732752-734080:- | gene-YMR243C_MUCL30387 | rna-NM_001182750.1_MUCL30387 | cds-NP_013970.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:739979-741307:- | gene-YMR243C_MUCL30388 | rna-NM_001182750.1_MUCL30388 | cds-NP_013970.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:728072-729400:- | gene-YMR243C_MUCL39482 | rna-NM_001182750.1_MUCL39482 | cds-NP_013970.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:735415-736743:- | gene-YMR243C_MUCL42920 | rna-NM_001182750.1_MUCL42920 | cds-NP_013970.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:754792-756120:- | gene-YMR243C_NCIM3186 | rna-NM_001182750.1_NCIM3186 | cds-NP_013970.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:727728-729056:- | gene-YMR243C_NCYC1407 | rna-NM_001182750.1_NCYC1407 | cds-NP_013970.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:737610-738938:- | gene-YMR243C_PE2H3 | rna-NM_001182750.1_PE2H3 | cds-NP_013970.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:738627-739955:- | gene-YMR243C_PE2H4 | rna-NM_001182750.1_PE2H4 | cds-NP_013970.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:754838-756166:- | gene-YMR243C_S288C | rna-NM_001182750.1_S288C | cds-NP_013970.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:51947-53275:+ | gene-YMR243C_SA1 | rna-NM_001182750.1_SA1 | cds-NP_013970.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:729598-730926:- | gene-YMR243C_ThermosaccDry | rna-NM_001182750.1_ThermosaccDry | cds-NP_013970.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:742144-743472:- | gene-YMR243C_VR1 | rna-NM_001182750.1_VR1 | cds-NP_013970.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:144734-146062:- | gene-YMR243C_ZTW1 | rna-NM_001182750.1_ZTW1 | cds-NP_013970.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:747451-748779:- | gene-YMR243C_Sparadoxus | rna-NM_001182750.1_Sparadoxus | cds-NP_013970.1_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |