ZPR1 (YGR211W)


Gene profile

Gene name: ZPR1
Reference locus (S288C): YGR211W
Gene biotype: protein_coding

Description: Essential protein with two zinc fingers; present in nucleus of growing cells, relocates to cytoplasm in starved cells via a process mediated by Cpr1p; binds translation elongation factor eEF-1 (Tef1p); relative distribution to nucleus increases upon DNA replication stress; human ZPR1 gene can complement yeast by allowing growth during down-regulation of yeast zpr1

Top 10 interactors (score): TEF2 (0.957); YTM1 (0.901); TEF1 (0.891); YGR210C (0.88); STI1 (0.854); OXR1 (0.854); SVF1 (0.838); ZUO1 (0.801); XDJ1 (0.792); CPR6 (0.759); SCJ1 (0.717); LHS1 (0.71); NCE103 (0.705); CPR1 (0.693); KRE33 (0.676); NNR1 (0.672); SPC98 (0.664); BUD13 (0.663); UBA4 (0.662); HSP42 (0.657)

Homologues (species, bitscore): ZPR1 (Homo sapiens, 380.6); Zpr1 (Mus musculus, 387.5); znf259 (Danio rerio, 390.6); znf259 (Xenopus tropicalis, 364.8); Zpr1 (Drosophila melanogaster, 336.3); W03F9.1 (Caenorhabditis elegans, 319.3); AT5G22480 (Arabidopsis thaliana, 350.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:880760-882220:+ gene-YGR211W_AKU4011 rna-NM_001181340.3_AKU4011 cds-NP_011727.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:161141-162601:+ gene-YGR211W_BG1 rna-NM_001181340.3_BG1 cds-NP_011727.3_BG1 99.4 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:888959-890419:+ gene-YGR211W_Bruggeman rna-NM_001181340.3_Bruggeman cds-NP_011727.3_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:886952-888412:+ gene-YGR211W_CAT1 rna-NM_001181340.3_CAT1 cds-NP_011727.3_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:884198-885658:+ gene-YGR211W_CBS1585 rna-NM_001181340.3_CBS1585 cds-NP_011727.3_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:887549-889009:+ gene-YGR211W_CBS436 rna-NM_001181340.3_CBS436 cds-NP_011727.3_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:875070-876530:+ gene-YGR211W_CBS6412 rna-NM_001181340.3_CBS6412 cds-NP_011727.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:881129-882589:+ gene-YGR211W_CBS6413 rna-NM_001181340.3_CBS6413 cds-NP_011727.3_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:914951-916411:+ gene-YGR211W_CENPK1137D rna-NM_001181340.3_CENPK1137D cds-NP_011727.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:869579-871039:+ gene-YGR211W_EthanolRed rna-NM_001181340.3_EthanolRed cds-NP_011727.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:873970-875430:+ gene-YGR211W_FaliES1 rna-NM_001181340.3_FaliES1 cds-NP_011727.3_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000148.1:31694-33154:+ gene-YGR211W_JAY291 rna-NM_001181340.3_JAY291 cds-NP_011727.3_JAY291 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:886443-887903:+ gene-YGR211W_MUCL30387 rna-NM_001181340.3_MUCL30387 cds-NP_011727.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:886127-887587:+ gene-YGR211W_MUCL30388 rna-NM_001181340.3_MUCL30388 cds-NP_011727.3_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:879274-880734:+ gene-YGR211W_MUCL39482 rna-NM_001181340.3_MUCL39482 cds-NP_011727.3_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:896820-898280:+ gene-YGR211W_MUCL42920 rna-NM_001181340.3_MUCL42920 cds-NP_011727.3_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:915241-916701:+ gene-YGR211W_NCIM3186 rna-NM_001181340.3_NCIM3186 cds-NP_011727.3_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:874930-876390:+ gene-YGR211W_NCYC1407 rna-NM_001181340.3_NCYC1407 cds-NP_011727.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:899536-900996:+ gene-YGR211W_PE2H3 rna-NM_001181340.3_PE2H3 cds-NP_011727.3_PE2H3 99.4 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:904646-906106:+ gene-YGR211W_PE2H4 rna-NM_001181340.3_PE2H4 cds-NP_011727.3_PE2H4 99.4 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:915241-916701:+ gene-YGR211W_S288C rna-NM_001181340.3_S288C cds-NP_011727.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000045.1:84690-86150:- gene-YGR211W_SA1 rna-NM_001181340.3_SA1 cds-NP_011727.3_SA1 99.4 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:894481-895941:+ gene-YGR211W_ThermosaccDry rna-NM_001181340.3_ThermosaccDry cds-NP_011727.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:998964-1000424:+ gene-YGR211W_VR1 rna-NM_001181340.3_VR1 cds-NP_011727.3_VR1 99.4 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:195922-197382:+ gene-YGR211W_ZTW1 rna-NM_001181340.3_ZTW1 cds-NP_011727.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:886411-887871:+ gene-YGR211W_Sparadoxus rna-NM_001181340.3_Sparadoxus cds-NP_011727.3_Sparadoxus 91.4 100.0 Verified 1 1 1 False True False False False

Additional files