YUH1 (YJR099W)


Gene profile

Gene name: YUH1
Reference locus (S288C): YJR099W
Gene biotype: protein_coding

Description: Ubiquitin C-terminal hydrolase; cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p; Belongs to the peptidase C12 family

Top 10 interactors (score): UBI4 (0.998); RPS31 (0.997); RUB1 (0.99); RPL40B (0.978); UBA1 (0.97); RPL40A (0.969); RPN11 (0.96); UBP6 (0.949); RRI1 (0.929); OTU2 (0.917); UBP14 (0.915); UBP2 (0.906); UBA3 (0.906); UBP1 (0.886); ULA1 (0.846); UBP3 (0.831); UBP15 (0.826); RPT1 (0.798); RPN8 (0.782); RPN1 (0.769)

Homologues (species, bitscore): UCHL3 (Homo sapiens, 117.9); Uchl3 (Mus musculus, 119.4); uchl3 (Danio rerio, 114.0); uchl3 (Xenopus tropicalis, 116.3); Uch (Drosophila melanogaster, 96.3); ubh-2 (Caenorhabditis elegans, 71.2); UCH3 (Arabidopsis thaliana, 90.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:587074-587784:+ gene-YJR099W_AKU4011 rna-NM_001181757.1_AKU4011 cds-NP_012633.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:19788-20498:- gene-YJR099W_BG1 rna-NM_001181757.1_BG1 cds-NP_012633.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:602807-603517:+ gene-YJR099W_Bruggeman rna-NM_001181757.1_Bruggeman cds-NP_012633.1_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:605226-605936:+ gene-YJR099W_CAT1 rna-NM_001181757.1_CAT1 cds-NP_012633.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:599139-599849:+ gene-YJR099W_CBS1585 rna-NM_001181757.1_CBS1585 cds-NP_012633.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:617246-617956:+ gene-YJR099W_CBS436 rna-NM_001181757.1_CBS436 cds-NP_012633.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:586286-586996:+ gene-YJR099W_CBS6412 rna-NM_001181757.1_CBS6412 cds-NP_012633.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:588547-589257:+ gene-YJR099W_CBS6413 rna-NM_001181757.1_CBS6413 cds-NP_012633.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:597892-598602:+ gene-YJR099W_CENPK1137D rna-NM_001181757.1_CENPK1137D cds-NP_012633.1_CENPK1137D 99.2 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:591491-592201:+ gene-YJR099W_EthanolRed rna-NM_001181757.1_EthanolRed cds-NP_012633.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:602957-603667:+ gene-YJR099W_FaliES1 rna-NM_001181757.1_FaliES1 cds-NP_012633.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000054.1:85750-86460:- gene-YJR099W_JAY291 rna-NM_001181757.1_JAY291 cds-NP_012633.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:601111-601821:+ gene-YJR099W_MUCL30387 rna-NM_001181757.1_MUCL30387 cds-NP_012633.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:598423-599133:+ gene-YJR099W_MUCL30388 rna-NM_001181757.1_MUCL30388 cds-NP_012633.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:592598-593308:+ gene-YJR099W_MUCL39482 rna-NM_001181757.1_MUCL39482 cds-NP_012633.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:596853-597563:+ gene-YJR099W_MUCL42920 rna-NM_001181757.1_MUCL42920 cds-NP_012633.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:615555-616265:+ gene-YJR099W_NCIM3186 rna-NM_001181757.1_NCIM3186 cds-NP_012633.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:590165-590875:+ gene-YJR099W_NCYC1407 rna-NM_001181757.1_NCYC1407 cds-NP_012633.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:608058-608768:+ gene-YJR099W_PE2H3 rna-NM_001181757.1_PE2H3 cds-NP_012633.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:601747-602457:+ gene-YJR099W_PE2H4 rna-NM_001181757.1_PE2H4 cds-NP_012633.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:615576-616286:+ gene-YJR099W_S288C rna-NM_001181757.1_S288C cds-NP_012633.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000038.1:74146-74856:+ gene-YJR099W_SA1 rna-NM_001181757.1_SA1 cds-NP_012633.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:596891-597601:+ gene-YJR099W_ThermosaccDry rna-NM_001181757.1_ThermosaccDry cds-NP_012633.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:599018-599728:+ gene-YJR099W_VR1 rna-NM_001181757.1_VR1 cds-NP_012633.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:576258-576968:+ gene-YJR099W_ZTW1 rna-NM_001181757.1_ZTW1 cds-NP_012633.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:609744-610454:+ gene-YJR099W_Sparadoxus rna-NM_001181757.1_Sparadoxus cds-NP_012633.1_Sparadoxus 85.6 100.0 Verified 1 1 1 False True False False False

Additional files