Gene name: YSP2
Reference locus (S288C): YDR326C
Gene biotype: protein_coding
Description: Membrane-anchored lipid-binding protein YSP2; Sterol-binding protein; has a probable role in retrograde transport of sterols from the plasma membrane to the ER; contains two StART-like domains that bind sterols and a GRAM domain; co-localizes to puncta in the cortical ER with Sip3p; one of six StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes
Top 10 interactors (score): LAM1 (0.908); SIP3 (0.896); PRY1 (0.747); PRY2 (0.695); YPK1 (0.663); ARE2 (0.655); UPC2 (0.648); SHE2 (0.637); PMD1 (0.582); OPI9 (0.574); KES1 (0.572); MFB1 (0.562); SCS2 (0.551); LNP1 (0.527); RAT1 (0.51); TCB2 (0.506); LAM4 (0.501); RAI1 (0.495); MDV1 (0.485); MRX8 (0.485)
Homologues (species, bitscore): GRAMD1A (Homo sapiens, 112.1); Gramd1a (Mus musculus, 111.7); gramd1ba (Danio rerio, 106.3); GRAMD1A (Xenopus tropicalis, 108.6); CG34394 (Drosophila melanogaster, 113.2); ZC328.3 (Caenorhabditis elegans, 111.3); VAD1 (Arabidopsis thaliana, 100.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1066650-1070966:- | gene-YDR326C_AKU4011 | rna-NM_001180634.1_AKU4011 | cds-NP_010613.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:60595-64911:+ | gene-YDR326C_BG1 | rna-NM_001180634.1_BG1 | cds-NP_010613.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1094193-1098509:- | gene-YDR326C_Bruggeman | rna-NM_001180634.1_Bruggeman | cds-NP_010613.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1080936-1085252:- | gene-YDR326C_CAT1 | rna-NM_001180634.1_CAT1 | cds-NP_010613.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1061094-1065410:- | gene-YDR326C_CBS1585 | rna-NM_001180634.1_CBS1585 | cds-NP_010613.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1079476-1083792:- | gene-YDR326C_CBS436 | rna-NM_001180634.1_CBS436 | cds-NP_010613.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1057782-1062098:- | gene-YDR326C_CBS6412 | rna-NM_001180634.1_CBS6412 | cds-NP_010613.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1079013-1083329:- | gene-YDR326C_CBS6413 | rna-NM_001180634.1_CBS6413 | cds-NP_010613.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1119247-1123563:- | gene-YDR326C_CENPK1137D | rna-NM_001180634.1_CENPK1137D | cds-NP_010613.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:242192-246508:- | gene-YDR326C_EthanolRed | rna-NM_001180634.1_EthanolRed | cds-NP_010613.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1073407-1077723:- | gene-YDR326C_FaliES1 | rna-NM_001180634.1_FaliES1 | cds-NP_010613.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000386.1:25916-30231:- | gene-YDR326C_JAY291 | rna-NM_001180634.1_JAY291 | cds-NP_010613.1_JAY291 | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1079437-1083753:- | gene-YDR326C_MUCL30387 | rna-NM_001180634.1_MUCL30387 | cds-NP_010613.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1068389-1072705:- | gene-YDR326C_MUCL30388 | rna-NM_001180634.1_MUCL30388 | cds-NP_010613.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1052901-1057217:- | gene-YDR326C_MUCL39482 | rna-NM_001180634.1_MUCL39482 | cds-NP_010613.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:999968-1004284:- | gene-YDR326C_MUCL42920 | rna-NM_001180634.1_MUCL42920 | cds-NP_010613.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1120532-1124848:- | gene-YDR326C_NCIM3186 | rna-NM_001180634.1_NCIM3186 | cds-NP_010613.1_NCIM3186 | 97.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1066192-1070508:- | gene-YDR326C_NCYC1407 | rna-NM_001180634.1_NCYC1407 | cds-NP_010613.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1077194-1081509:- | gene-YDR326C_PE2H3 | rna-NM_001180634.1_PE2H3 | cds-NP_010613.1_PE2H3 | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1082779-1087094:- | gene-YDR326C_PE2H4 | rna-NM_001180634.1_PE2H4 | cds-NP_010613.1_PE2H4 | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1120609-1124925:- | gene-YDR326C_S288C | rna-NM_001180634.1_S288C | cds-NP_010613.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:91422-95738:- | gene-YDR326C_SA1 | rna-NM_001180634.1_SA1 | cds-NP_010613.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1077680-1081996:- | gene-YDR326C_ThermosaccDry | rna-NM_001180634.1_ThermosaccDry | cds-NP_010613.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1093593-1097909:- | gene-YDR326C_VR1 | rna-NM_001180634.1_VR1 | cds-NP_010613.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:121790-126106:- | gene-YDR326C_ZTW1 | rna-NM_001180634.1_ZTW1 | cds-NP_010613.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1073110-1077438:- | gene-YDR326C_Sparadoxus | rna-NM_001180634.1_Sparadoxus | cds-NP_010613.1_Sparadoxus | 89.6 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |