Gene name: YRF1-2
Reference locus (S288C): YER190W
Gene biotype: protein_coding
Description: Y' element ATP-dependent helicase protein 1 copy 2; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; induced by treatment with 8-methoxypsoralen and UVA irradiation
Top 10 interactors (score): YER189W (0.963); YER188C-A (0.906); YML133C (0.873); YLL066C (0.873); YJL225C (0.873); YLL067C (0.873); YBL113C (0.873); YRF1-3 (0.873); YRF1-5 (0.873); YIL177C (0.873); YRF1-6 (0.873); YRF1-4 (0.873); YRF1-7 (0.873); YEL077C (0.873); YHL050C (0.872); YHR219W (0.872); YBL112C (0.872); YRF1-1 (0.872); YHR218W (0.858); YFL066C (0.843)
Homologues (species, bitscore): EIF4A1 (Homo sapiens, 50.8); Eif4a1 (Mus musculus, 50.8); mia3 (Danio rerio, 56.6); eif4a1 (Xenopus tropicalis, 51.2); CG15765 (Drosophila melanogaster, 73.2); inf-1 (Caenorhabditis elegans, 52.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1478065-1479259:+ | gene-YER190W_CAT1 | rna-NM_001179080.3_CAT1 | cds-NP_011117.3_CAT1 | 15.9 | 23.6 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | JH711429.1:1-290:- | gene-YER190W_CENPK1137D | rna-NM_001179080.3_CENPK1137D | cds-NP_011117.3_CENPK1137D | 5.7 | 5.7 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:4389-8089:- | gene-YER190W_MUCL42920 | rna-NM_001179080.3_MUCL42920 | cds-NP_011117.3_MUCL42920 | 54.4 | 73.2 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:571479-576524:+ | gene-YER190W_NCIM3186 | rna-NM_001179080.3_NCIM3186 | cds-NP_011117.3_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:916086-917654:+ | gene-YER190W_PE2H3 | rna-NM_001179080.3_PE2H3 | cds-NP_011117.3_PE2H3 | 30.8 | 31.0 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:571480-576525:+ | gene-YER190W_S288C | rna-NM_001179080.3_S288C | cds-NP_011117.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:6749-7239:- | gene-YER190W_VR1 | rna-NM_001179080.3_VR1 | cds-NP_011117.3_VR1 | 9.6 | 9.7 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:1072935-1077999:+ | gene-YER190W_Sparadoxus | rna-NM_001179080.3_Sparadoxus | cds-NP_011117.3_Sparadoxus | 96.8 | 99.6 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |