Gene name: YRF1-1
Reference locus (S288C): YDR545W
Gene biotype: protein_coding
Description: Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
Top 10 interactors (score): YDR545C-A (0.918); YLL066C (0.873); YLL067C (0.873); YIL177C (0.873); YML133C (0.873); YJL225C (0.873); YEL077C (0.873); YRF1-4 (0.872); YRF1-7 (0.872); YRF1-2 (0.872); YBL112C (0.872); YRF1-5 (0.872); YRF1-3 (0.872); YBL113C (0.872); YHL050C (0.872); YHR218W (0.872); YRF1-6 (0.872); YHR219W (0.872); YBL111C (0.868); YDR543C (0.865)
Homologues (species, bitscore): EIF4A1 (Homo sapiens, 51.2); Eif4a1 (Mus musculus, 51.2); mia3 (Danio rerio, 57.4); eif4a1 (Xenopus tropicalis, 51.2); CG15765 (Drosophila melanogaster, 72.8); inf-1 (Caenorhabditis elegans, 52.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:4667-5322:- | gene-YDR545W_CAT1 | rna-NM_001180853.1_CAT1 | cds-NP_010834.1_CAT1 | 11.2 | 12.1 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1526244-1531634:+ | gene-YDR545W_NCIM3186 | rna-NM_001180853.1_NCIM3186 | cds-NP_010834.1_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1526321-1531711:+ | gene-YDR545W_S288C | rna-NM_001180853.1_S288C | cds-NP_010834.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:468-5879:- | gene-YDR545W_Sparadoxus | rna-NM_001180853.1_Sparadoxus | cds-NP_010834.1_Sparadoxus | 97.0 | 99.7 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |