YRB2 (YIL063C)


Gene profile

Gene name: YRB2
Reference locus (S288C): YIL063C
Gene biotype: protein_coding

Description: Ran-specific GTPase-activating protein 2; Protein of unknown function; involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; relocalizes to the cytosol in response to hypoxia; not essential for viability

Top 10 interactors (score): GSP1 (0.998); CRM1 (0.997); UBC9 (0.995); NSP1 (0.986); MEX67 (0.981); RNA1 (0.97); NUP2 (0.965); HDA1 (0.943); SMT3 (0.943); NTF2 (0.93); YRB1 (0.928); YRA1 (0.927); PFS2 (0.925); SSE1 (0.918); SSE2 (0.917); SSA1 (0.912); SSA2 (0.912); KAR2 (0.911); NAB3 (0.911); SSA4 (0.911)

Homologues (species, bitscore): RANBP3 (Homo sapiens, 73.6); Ranbp3 (Mus musculus, 72.0); ranbp3a (Danio rerio, 80.5); ranbp3 (Xenopus tropicalis, 78.6); Nup358 (Drosophila melanogaster, 69.3); npp-9 (Caenorhabditis elegans, 55.5); SIRANBP (Arabidopsis thaliana, 60.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:239429-240412:- gene-YIL063C_AKU4011 rna-NM_001179413.1_AKU4011 cds-NP_012201.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:101358-102341:- gene-YIL063C_BG1 rna-NM_001179413.1_BG1 cds-NP_012201.1_BG1 98.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:244844-245827:- gene-YIL063C_Bruggeman rna-NM_001179413.1_Bruggeman cds-NP_012201.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:235119-236102:- gene-YIL063C_CAT1 rna-NM_001179413.1_CAT1 cds-NP_012201.1_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:239000-239983:- gene-YIL063C_CBS1585 rna-NM_001179413.1_CBS1585 cds-NP_012201.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:235047-236030:- gene-YIL063C_CBS436 rna-NM_001179413.1_CBS436 cds-NP_012201.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:236375-237358:- gene-YIL063C_CBS6412 rna-NM_001179413.1_CBS6412 cds-NP_012201.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:230920-231903:- gene-YIL063C_CBS6413 rna-NM_001179413.1_CBS6413 cds-NP_012201.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:234810-235793:- gene-YIL063C_CENPK1137D rna-NM_001179413.1_CENPK1137D cds-NP_012201.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:223727-224710:- gene-YIL063C_EthanolRed rna-NM_001179413.1_EthanolRed cds-NP_012201.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:240630-241613:- gene-YIL063C_FaliES1 rna-NM_001179413.1_FaliES1 cds-NP_012201.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000365.1:56520-57503:+ gene-YIL063C_JAY291 rna-NM_001179413.1_JAY291 cds-NP_012201.1_JAY291 98.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:243064-244047:- gene-YIL063C_MUCL30387 rna-NM_001179413.1_MUCL30387 cds-NP_012201.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:239669-240652:- gene-YIL063C_MUCL30388 rna-NM_001179413.1_MUCL30388 cds-NP_012201.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:239846-240829:- gene-YIL063C_MUCL39482 rna-NM_001179413.1_MUCL39482 cds-NP_012201.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:243210-244193:- gene-YIL063C_MUCL42920 rna-NM_001179413.1_MUCL42920 cds-NP_012201.1_MUCL42920 98.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:242761-243744:- gene-YIL063C_NCIM3186 rna-NM_001179413.1_NCIM3186 cds-NP_012201.1_NCIM3186 98.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:244122-245105:- gene-YIL063C_NCYC1407 rna-NM_001179413.1_NCYC1407 cds-NP_012201.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:238102-239085:- gene-YIL063C_PE2H3 rna-NM_001179413.1_PE2H3 cds-NP_012201.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:232817-233800:- gene-YIL063C_PE2H4 rna-NM_001179413.1_PE2H4 cds-NP_012201.1_PE2H4 98.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:242761-243744:- gene-YIL063C_S288C rna-NM_001179413.1_S288C cds-NP_012201.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000031.1:82097-83080:+ gene-YIL063C_SA1 rna-NM_001179413.1_SA1 cds-NP_012201.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:239293-240276:- gene-YIL063C_ThermosaccDry rna-NM_001179413.1_ThermosaccDry cds-NP_012201.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:236976-237959:- gene-YIL063C_VR1 rna-NM_001179413.1_VR1 cds-NP_012201.1_VR1 99.0 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:213555-214538:- gene-YIL063C_ZTW1 rna-NM_001179413.1_ZTW1 cds-NP_012201.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:237640-238623:- gene-YIL063C_Sparadoxus rna-NM_001179413.1_Sparadoxus cds-NP_012201.1_Sparadoxus 89.5 99.6 Verified 1 1 1 False True False False False

Additional files