Gene name: YRA1
Reference locus (S288C): YDR381W
Gene biotype: protein_coding
Description: Nuclear polyadenylated RNA-binding protein; required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA export with 3' end processing via its interactions with Mex67p and Pcf11p; interacts with DBP2; inhibits the helicase activity of Dbp2; functionally redundant with Yra2p, another REF family member
Top 10 interactors (score): THO2 (0.999); MEX67 (0.999); SUB2 (0.999); PCF11 (0.998); NAB2 (0.997); STO1 (0.996); CBC2 (0.993); MLP1 (0.993); HPR1 (0.992); THP2 (0.992); MFT1 (0.986); NPL3 (0.981); NUP1 (0.977); GLE2 (0.972); NIC96 (0.966); NUP170 (0.964); GBP2 (0.964); NUP188 (0.964); NUP2 (0.963); DBP2 (0.953)
Homologues (species, bitscore): Alyref2 (Mus musculus, 50.8); aly-1 (Caenorhabditis elegans, 59.7); ALY4 (Arabidopsis thaliana, 54.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:571952-573397:+ | gene-YDR381W_AKU4011 | rna-NM_001180689.1_AKU4011 | cds-NP_010669.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000039.1:55250-56696:+ | gene-YDR381W_BG1 | rna-NM_001180689.1_BG1 | cds-NP_010669.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1207340-1208786:+ | gene-YDR381W_Bruggeman | rna-NM_001180689.1_Bruggeman | cds-NP_010669.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1185942-1187388:+ | gene-YDR381W_CAT1 | rna-NM_001180689.1_CAT1 | cds-NP_010669.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1171444-1172889:+ | gene-YDR381W_CBS1585 | rna-NM_001180689.1_CBS1585 | cds-NP_010669.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1189995-1191441:+ | gene-YDR381W_CBS436 | rna-NM_001180689.1_CBS436 | cds-NP_010669.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1167681-1169126:+ | gene-YDR381W_CBS6412 | rna-NM_001180689.1_CBS6412 | cds-NP_010669.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1189571-1191016:+ | gene-YDR381W_CBS6413 | rna-NM_001180689.1_CBS6413 | cds-NP_010669.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1235211-1236657:+ | gene-YDR381W_CENPK1137D | rna-NM_001180689.1_CENPK1137D | cds-NP_010669.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:1181101-1182546:+ | gene-YDR381W_EthanolRed | rna-NM_001180689.1_EthanolRed | cds-NP_010669.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1184388-1185833:+ | gene-YDR381W_FaliES1 | rna-NM_001180689.1_FaliES1 | cds-NP_010669.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000057.1:5249-6695:- | gene-YDR381W_JAY291 | rna-NM_001180689.1_JAY291 | cds-NP_010669.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1190653-1192099:+ | gene-YDR381W_MUCL30387 | rna-NM_001180689.1_MUCL30387 | cds-NP_010669.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1173263-1174709:+ | gene-YDR381W_MUCL30388 | rna-NM_001180689.1_MUCL30388 | cds-NP_010669.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1162995-1164440:+ | gene-YDR381W_MUCL39482 | rna-NM_001180689.1_MUCL39482 | cds-NP_010669.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:1105391-1106837:+ | gene-YDR381W_MUCL42920 | rna-NM_001180689.1_MUCL42920 | cds-NP_010669.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1236481-1237927:+ | gene-YDR381W_NCIM3186 | rna-NM_001180689.1_NCIM3186 | cds-NP_010669.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1176966-1178411:+ | gene-YDR381W_NCYC1407 | rna-NM_001180689.1_NCYC1407 | cds-NP_010669.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1187049-1188495:+ | gene-YDR381W_PE2H3 | rna-NM_001180689.1_PE2H3 | cds-NP_010669.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1192630-1194076:+ | gene-YDR381W_PE2H4 | rna-NM_001180689.1_PE2H4 | cds-NP_010669.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1236558-1238004:+ | gene-YDR381W_S288C | rna-NM_001180689.1_S288C | cds-NP_010669.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000072.1:55331-56777:+ | gene-YDR381W_SA1 | rna-NM_001180689.1_SA1 | cds-NP_010669.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1188669-1190114:+ | gene-YDR381W_ThermosaccDry | rna-NM_001180689.1_ThermosaccDry | cds-NP_010669.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:616005-617451:+ | gene-YDR381W_VR1 | rna-NM_001180689.1_VR1 | cds-NP_010669.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:231495-232940:+ | gene-YDR381W_ZTW1 | rna-NM_001180689.1_ZTW1 | cds-NP_010669.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1183205-1184650:+ | gene-YDR381W_Sparadoxus | rna-NM_001180689.1_Sparadoxus | cds-NP_010669.1_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |