Gene name: YPT6
Reference locus (S288C): YLR262C
Gene biotype: protein_coding
Description: GTP-binding protein YPT6; Rab family GTPase; required for endosome-to-Golgii, intra-Golgi retrograde, and retrograde Golgi-to-ER transport; temporarily at the Golgi, dissociating into the cytosol on arrival of the late Golgi GTPase Ypt32p; Golgi-localized form is GTP bound, while cytosolic form is GDP-bound; required for delivery of Atg9p to the phagophore assembly site during autophagy under heat stress, with Ypt6p for starvation induced autophagy and for the CVT pathway; homolog of mammalian Rab6
Top 10 interactors (score): GDI1 (0.999); VAM6 (0.999); SGM1 (0.994); VPS53 (0.99); VPS52 (0.99); RGP1 (0.989); RIC1 (0.989); TLG1 (0.988); ARL1 (0.984); MRS6 (0.983); VPS33 (0.975); GYP6 (0.972); TLG2 (0.972); VPS63 (0.966); IMH1 (0.961); VPS35 (0.959); COG6 (0.958); COG8 (0.956); VPS54 (0.941); SYS1 (0.935)
Homologues (species, bitscore): RAB6B (Homo sapiens, 259.2); Rab6a (Mus musculus, 259.6); rab6b (Danio rerio, 257.7); rab41 (Xenopus tropicalis, 258.5); Rab6 (Drosophila melanogaster, 262.3); rab-6.1 (Caenorhabditis elegans, 261.9); RAB6A (Arabidopsis thaliana, 255.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:616509-617156:- | gene-YLR262C_AKU4011 | rna-NM_001182149.1_AKU4011 | cds-NP_013363.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:114737-115384:+ | gene-YLR262C_BG1 | rna-NM_001182149.1_BG1 | cds-NP_013363.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:650751-651398:- | gene-YLR262C_Bruggeman | rna-NM_001182149.1_Bruggeman | cds-NP_013363.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:649935-650582:- | gene-YLR262C_CAT1 | rna-NM_001182149.1_CAT1 | cds-NP_013363.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:652004-652651:- | gene-YLR262C_CBS1585 | rna-NM_001182149.1_CBS1585 | cds-NP_013363.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:636226-636873:- | gene-YLR262C_CBS436 | rna-NM_001182149.1_CBS436 | cds-NP_013363.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:614979-615626:- | gene-YLR262C_CBS6412 | rna-NM_001182149.1_CBS6412 | cds-NP_013363.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:652300-652947:- | gene-YLR262C_CBS6413 | rna-NM_001182149.1_CBS6413 | cds-NP_013363.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:652827-653474:- | gene-YLR262C_CENPK1137D | rna-NM_001182149.1_CENPK1137D | cds-NP_013363.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:610709-611356:- | gene-YLR262C_EthanolRed | rna-NM_001182149.1_EthanolRed | cds-NP_013363.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:639540-640187:- | gene-YLR262C_FaliES1 | rna-NM_001182149.1_FaliES1 | cds-NP_013363.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000136.1:19224-19871:+ | gene-YLR262C_JAY291 | rna-NM_001182149.1_JAY291 | cds-NP_013363.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:651611-652258:- | gene-YLR262C_MUCL30387 | rna-NM_001182149.1_MUCL30387 | cds-NP_013363.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:656376-657023:- | gene-YLR262C_MUCL30388 | rna-NM_001182149.1_MUCL30388 | cds-NP_013363.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:652985-653632:- | gene-YLR262C_MUCL39482 | rna-NM_001182149.1_MUCL39482 | cds-NP_013363.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:647755-648402:- | gene-YLR262C_MUCL42920 | rna-NM_001182149.1_MUCL42920 | cds-NP_013363.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:668218-668865:- | gene-YLR262C_NCIM3186 | rna-NM_001182149.1_NCIM3186 | cds-NP_013363.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:639972-640619:- | gene-YLR262C_NCYC1407 | rna-NM_001182149.1_NCYC1407 | cds-NP_013363.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:643741-644388:- | gene-YLR262C_PE2H3 | rna-NM_001182149.1_PE2H3 | cds-NP_013363.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:643485-644132:- | gene-YLR262C_PE2H4 | rna-NM_001182149.1_PE2H4 | cds-NP_013363.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:668244-668891:- | gene-YLR262C_S288C | rna-NM_001182149.1_S288C | cds-NP_013363.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:19469-20116:+ | gene-YLR262C_SA1 | rna-NM_001182149.1_SA1 | cds-NP_013363.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:641503-642150:- | gene-YLR262C_ThermosaccDry | rna-NM_001182149.1_ThermosaccDry | cds-NP_013363.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:652817-653464:- | gene-YLR262C_VR1 | rna-NM_001182149.1_VR1 | cds-NP_013363.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:165794-166441:- | gene-YLR262C_ZTW1 | rna-NM_001182149.1_ZTW1 | cds-NP_013363.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:627297-627944:- | gene-YLR262C_Sparadoxus | rna-NM_001182149.1_Sparadoxus | cds-NP_013363.1_Sparadoxus | 92.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |