Gene name: YPT53
Reference locus (S288C): YNL093W
Gene biotype: protein_coding
Description: GTP-binding protein YPT53; Stress-induced Rab family GTPase; required for vacuolar protein sorting and endocytosis; involved in ionic stress tolerance; similar to Vps21p and Ypt52p; functional homolog of Vps21p; mammalian Rab5 homolog; YPT53 has a paralog, VPS21, that arose from the whole genome duplication
Top 10 interactors (score): VPS9 (0.996); MRS6 (0.979); VPS33 (0.97); PEP7 (0.954); GDI1 (0.947); VPS8 (0.934); YPT52 (0.87); VPS21 (0.843); MON1 (0.838); YPT7 (0.825); MSB3 (0.798); VAM6 (0.79); VPS3 (0.784); GYP7 (0.775); MUK1 (0.769); VPS45 (0.761); VPS34 (0.757); SEC4 (0.753); YNL089C (0.746); ROY1 (0.746)
Homologues (species, bitscore): RAB5A (Homo sapiens, 188.3); Rab5a (Mus musculus, 188.3); rab5ab (Danio rerio, 188.0); rab5a (Xenopus tropicalis, 184.9); Rab5 (Drosophila melanogaster, 186.4); rab-5 (Caenorhabditis elegans, 182.2); ARA6 (Arabidopsis thaliana, 170.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:443512-444174:+ | gene-YNL093W_AKU4011 | rna-NM_001182931.3_AKU4011 | cds-NP_014306.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:347599-348261:+ | gene-YNL093W_BG1 | rna-NM_001182931.3_BG1 | cds-NP_014306.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:454231-454893:+ | gene-YNL093W_Bruggeman | rna-NM_001182931.3_Bruggeman | cds-NP_014306.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:497261-497923:+ | gene-YNL093W_CAT1 | rna-NM_001182931.3_CAT1 | cds-NP_014306.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:444182-444844:+ | gene-YNL093W_CBS1585 | rna-NM_001182931.3_CBS1585 | cds-NP_014306.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:512576-513238:+ | gene-YNL093W_CBS436 | rna-NM_001182931.3_CBS436 | cds-NP_014306.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:439278-439940:+ | gene-YNL093W_CBS6412 | rna-NM_001182931.3_CBS6412 | cds-NP_014306.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:440594-441256:+ | gene-YNL093W_CBS6413 | rna-NM_001182931.3_CBS6413 | cds-NP_014306.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:443691-444353:+ | gene-YNL093W_CENPK1137D | rna-NM_001182931.3_CENPK1137D | cds-NP_014306.3_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:446337-446999:+ | gene-YNL093W_EthanolRed | rna-NM_001182931.3_EthanolRed | cds-NP_014306.3_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:436866-437528:+ | gene-YNL093W_FaliES1 | rna-NM_001182931.3_FaliES1 | cds-NP_014306.3_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000317.1:36070-36732:- | gene-YNL093W_JAY291 | rna-NM_001182931.3_JAY291 | cds-NP_014306.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:450407-451069:+ | gene-YNL093W_MUCL30387 | rna-NM_001182931.3_MUCL30387 | cds-NP_014306.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:485779-486441:+ | gene-YNL093W_MUCL30388 | rna-NM_001182931.3_MUCL30388 | cds-NP_014306.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:441586-442248:+ | gene-YNL093W_MUCL39482 | rna-NM_001182931.3_MUCL39482 | cds-NP_014306.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:445527-446189:+ | gene-YNL093W_MUCL42920 | rna-NM_001182931.3_MUCL42920 | cds-NP_014306.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:449837-450499:+ | gene-YNL093W_NCIM3186 | rna-NM_001182931.3_NCIM3186 | cds-NP_014306.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:443634-444296:+ | gene-YNL093W_NCYC1407 | rna-NM_001182931.3_NCYC1407 | cds-NP_014306.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:446872-447534:+ | gene-YNL093W_PE2H3 | rna-NM_001182931.3_PE2H3 | cds-NP_014306.3_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:441948-442610:+ | gene-YNL093W_PE2H4 | rna-NM_001182931.3_PE2H4 | cds-NP_014306.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:449868-450530:+ | gene-YNL093W_S288C | rna-NM_001182931.3_S288C | cds-NP_014306.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000024.1:34811-35473:+ | gene-YNL093W_SA1 | rna-NM_001182931.3_SA1 | cds-NP_014306.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:437741-438403:+ | gene-YNL093W_ThermosaccDry | rna-NM_001182931.3_ThermosaccDry | cds-NP_014306.3_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:456853-457515:+ | gene-YNL093W_VR1 | rna-NM_001182931.3_VR1 | cds-NP_014306.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:347090-347752:+ | gene-YNL093W_ZTW1 | rna-NM_001182931.3_ZTW1 | cds-NP_014306.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:453252-453914:+ | gene-YNL093W_Sparadoxus | rna-NM_001182931.3_Sparadoxus | cds-NP_014306.3_Sparadoxus | 86.9 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |