Gene name: YPT1
Reference locus (S288C): YFL038C
Gene biotype: protein_coding
Description: GTP-binding protein YPT1; Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles
Top 10 interactors (score): SEC23 (0.999); TRS23 (0.999); BET5 (0.999); GDI1 (0.999); BET3 (0.999); USO1 (0.999); TRS31 (0.998); SAR1 (0.997); SEC4 (0.996); SED5 (0.995); TRS85 (0.995); MRS6 (0.995); SEC22 (0.992); TRS120 (0.991); TRS33 (0.991); TRS20 (0.99); YPT31 (0.99); YIP1 (0.989); TRS130 (0.989); GYP1 (0.988)
Homologues (species, bitscore): RAB1A (Homo sapiens, 305.8); Rab1 (Mus musculus, 305.8); rab1ba (Danio rerio, 303.5); rab1a (Xenopus tropicalis, 292.4); Rab1 (Drosophila melanogaster, 278.1); rab-1 (Caenorhabditis elegans, 284.6); RA-5 (Arabidopsis thaliana, 287.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:51701-52321:- | gene-YFL038C_AKU4011 | rna-NM_001179928.1_AKU4011 | cds-NP_116615.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000182.1:17467-18087:+ | gene-YFL038C_BG1 | rna-NM_001179928.1_BG1 | cds-NP_116615.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:50585-51205:- | gene-YFL038C_Bruggeman | rna-NM_001179928.1_Bruggeman | cds-NP_116615.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:55471-56091:- | gene-YFL038C_CAT1 | rna-NM_001179928.1_CAT1 | cds-NP_116615.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:52379-52999:- | gene-YFL038C_CBS1585 | rna-NM_001179928.1_CBS1585 | cds-NP_116615.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:26018-26638:- | gene-YFL038C_CBS436 | rna-NM_001179928.1_CBS436 | cds-NP_116615.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:52618-53238:- | gene-YFL038C_CBS6412 | rna-NM_001179928.1_CBS6412 | cds-NP_116615.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:54777-55397:- | gene-YFL038C_CBS6413 | rna-NM_001179928.1_CBS6413 | cds-NP_116615.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:51691-52311:- | gene-YFL038C_CENPK1137D | rna-NM_001179928.1_CENPK1137D | cds-NP_116615.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:51044-51664:- | gene-YFL038C_EthanolRed | rna-NM_001179928.1_EthanolRed | cds-NP_116615.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:52253-52873:- | gene-YFL038C_FaliES1 | rna-NM_001179928.1_FaliES1 | cds-NP_116615.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000448.1:60711-61331:- | gene-YFL038C_JAY291 | rna-NM_001179928.1_JAY291 | cds-NP_116615.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:52671-53291:- | gene-YFL038C_MUCL30387 | rna-NM_001179928.1_MUCL30387 | cds-NP_116615.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:50572-51192:- | gene-YFL038C_MUCL30388 | rna-NM_001179928.1_MUCL30388 | cds-NP_116615.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:50895-51515:- | gene-YFL038C_MUCL39482 | rna-NM_001179928.1_MUCL39482 | cds-NP_116615.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:48601-49221:- | gene-YFL038C_MUCL42920 | rna-NM_001179928.1_MUCL42920 | cds-NP_116615.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:55365-55985:- | gene-YFL038C_NCIM3186 | rna-NM_001179928.1_NCIM3186 | cds-NP_116615.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:51966-52586:- | gene-YFL038C_NCYC1407 | rna-NM_001179928.1_NCYC1407 | cds-NP_116615.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:71865-72485:- | gene-YFL038C_PE2H3 | rna-NM_001179928.1_PE2H3 | cds-NP_116615.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:71416-72036:- | gene-YFL038C_PE2H4 | rna-NM_001179928.1_PE2H4 | cds-NP_116615.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:55366-55986:- | gene-YFL038C_S288C | rna-NM_001179928.1_S288C | cds-NP_116615.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000004.1:279649-280269:+ | gene-YFL038C_SA1 | rna-NM_001179928.1_SA1 | cds-NP_116615.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:51441-52061:- | gene-YFL038C_ThermosaccDry | rna-NM_001179928.1_ThermosaccDry | cds-NP_116615.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:59989-60609:- | gene-YFL038C_VR1 | rna-NM_001179928.1_VR1 | cds-NP_116615.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000012.1:36737-37357:- | gene-YFL038C_ZTW1 | rna-NM_001179928.1_ZTW1 | cds-NP_116615.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:75786-76406:- | gene-YFL038C_Sparadoxus | rna-NM_001179928.1_Sparadoxus | cds-NP_116615.1_Sparadoxus | 92.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |