YPS3 (YLR121C)


Gene profile

Gene name: YPS3
Reference locus (S288C): YLR121C
Gene biotype: protein_coding

Description: Aspartic proteinase yapsin-3; Aspartic protease; member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor; Belongs to the peptidase A1 family

Top 10 interactors (score): NCW2 (0.873); PRB1 (0.727); DDI1 (0.717); YPS1 (0.672); MSB2 (0.653); IRC22 (0.62); PST1 (0.615); PIR3 (0.609); TOH1 (0.606); YPS5 (0.565); YIL082W-A (0.562); PRC1 (0.558); STE24 (0.552); PRY2 (0.543); CRH1 (0.534); KEX2 (0.531); YSP3 (0.522); KEX1 (0.504); YGR109W-B (0.499); PLB3 (0.498)

Homologues (species, bitscore): PGC (Homo sapiens, 129.0); Cym (Mus musculus, 109.0); NAPSA (Danio rerio, 95.5); pga4 (Xenopus tropicalis, 116.7); CG5860 (Drosophila melanogaster, 99.8); asp-1 (Caenorhabditis elegans, 94.4); AT1G62290 (Arabidopsis thaliana, 80.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:371227-372753:- gene-YLR121C_AKU4011 rna-NM_001182008.1_AKU4011 cds-NP_013222.1_AKU4011 99.4 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:335003-336529:- gene-YLR121C_BG1 rna-NM_001182008.1_BG1 cds-NP_013222.1_BG1 99.0 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:382351-383877:- gene-YLR121C_Bruggeman rna-NM_001182008.1_Bruggeman cds-NP_013222.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:382268-383794:- gene-YLR121C_CAT1 rna-NM_001182008.1_CAT1 cds-NP_013222.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:378370-379896:- gene-YLR121C_CBS1585 rna-NM_001182008.1_CBS1585 cds-NP_013222.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:368608-370134:- gene-YLR121C_CBS436 rna-NM_001182008.1_CBS436 cds-NP_013222.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:376788-378314:- gene-YLR121C_CBS6412 rna-NM_001182008.1_CBS6412 cds-NP_013222.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:378636-380162:- gene-YLR121C_CBS6413 rna-NM_001182008.1_CBS6413 cds-NP_013222.1_CBS6413 99.4 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:373766-375292:- gene-YLR121C_CENPK1137D rna-NM_001182008.1_CENPK1137D cds-NP_013222.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:371428-372954:- gene-YLR121C_EthanolRed rna-NM_001182008.1_EthanolRed cds-NP_013222.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:370939-372465:- gene-YLR121C_FaliES1 rna-NM_001182008.1_FaliES1 cds-NP_013222.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000117.1:20733-22259:+ gene-YLR121C_JAY291 rna-NM_001182008.1_JAY291 cds-NP_013222.1_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:378643-380169:- gene-YLR121C_MUCL30387 rna-NM_001182008.1_MUCL30387 cds-NP_013222.1_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:387424-388950:- gene-YLR121C_MUCL30388 rna-NM_001182008.1_MUCL30388 cds-NP_013222.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:378879-380405:- gene-YLR121C_MUCL39482 rna-NM_001182008.1_MUCL39482 cds-NP_013222.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:379005-380531:- gene-YLR121C_MUCL42920 rna-NM_001182008.1_MUCL42920 cds-NP_013222.1_MUCL42920 99.4 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:388718-390244:- gene-YLR121C_NCIM3186 rna-NM_001182008.1_NCIM3186 cds-NP_013222.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:371152-372678:- gene-YLR121C_NCYC1407 rna-NM_001182008.1_NCYC1407 cds-NP_013222.1_NCYC1407 99.4 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:376713-378239:- gene-YLR121C_PE2H3 rna-NM_001182008.1_PE2H3 cds-NP_013222.1_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:376454-377980:- gene-YLR121C_PE2H4 rna-NM_001182008.1_PE2H4 cds-NP_013222.1_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:388744-390270:- gene-YLR121C_S288C rna-NM_001182008.1_S288C cds-NP_013222.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000055.1:14619-16145:- gene-YLR121C_SA1 rna-NM_001182008.1_SA1 cds-NP_013222.1_SA1 99.6 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:372149-373675:- gene-YLR121C_ThermosaccDry rna-NM_001182008.1_ThermosaccDry cds-NP_013222.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:384608-386134:- gene-YLR121C_VR1 rna-NM_001182008.1_VR1 cds-NP_013222.1_VR1 98.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:369947-371473:- gene-YLR121C_ZTW1 rna-NM_001182008.1_ZTW1 cds-NP_013222.1_ZTW1 99.4 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:379767-381293:- gene-YLR121C_Sparadoxus rna-NM_001182008.1_Sparadoxus cds-NP_013222.1_Sparadoxus 89.1 100.0 Verified 1 1 1 False True False False False

Additional files