YPQ2 (YDR352W)


Gene profile

Gene name: YPQ2
Reference locus (S288C): YDR352W
Gene biotype: protein_coding

Description: Putative vacuolar membrane transporter for cationic amino acids; likely contributes to amino acid homeostasis by exporting cationic amino acids from the vacuole; member of the PQ-loop family, with seven transmembrane domains; mutant phenotype is functionally complemented by rat PQLC2 vacuolar transporter; Belongs to the laat-1 family

Top 10 interactors (score): ERS1 (0.822); NCR1 (0.816); YPL162C (0.766); YDR090C (0.745); ANY1 (0.744); SNA2 (0.718); SNA4 (0.695); VBA4 (0.692); SSH4 (0.65); FTH1 (0.631); OCA2 (0.619); PMC1 (0.584); AVT1 (0.571); TUL1 (0.568); MPC2 (0.561); MPC3 (0.499); VCX1 (0.487); SEC7 (0.481); ZRT3 (0.454); COT1 (0.453)

Homologues (species, bitscore): PQLC2 (Homo sapiens, 94.0); Pqlc2 (Mus musculus, 84.0); pqlc2 (Danio rerio, 92.8); C3orf55 (Xenopus tropicalis, 102.1); Y43H11AL.2 (Caenorhabditis elegans, 104.4); AT4G20100 (Arabidopsis thaliana, 93.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1127865-1128818:+ gene-YDR352W_AKU4011 rna-NM_001180660.1_AKU4011 cds-NP_010639.1_AKU4011 98.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:6413-7366:+ gene-YDR352W_BG1 rna-NM_001180660.1_BG1 cds-NP_010639.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1158518-1159471:+ gene-YDR352W_Bruggeman rna-NM_001180660.1_Bruggeman cds-NP_010639.1_Bruggeman 98.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1137107-1138060:+ gene-YDR352W_CAT1 rna-NM_001180660.1_CAT1 cds-NP_010639.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1122582-1123535:+ gene-YDR352W_CBS1585 rna-NM_001180660.1_CBS1585 cds-NP_010639.1_CBS1585 98.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1141164-1142117:+ gene-YDR352W_CBS436 rna-NM_001180660.1_CBS436 cds-NP_010639.1_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1118842-1119795:+ gene-YDR352W_CBS6412 rna-NM_001180660.1_CBS6412 cds-NP_010639.1_CBS6412 98.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1140732-1141685:+ gene-YDR352W_CBS6413 rna-NM_001180660.1_CBS6413 cds-NP_010639.1_CBS6413 98.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1180447-1181400:+ gene-YDR352W_CENPK1137D rna-NM_001180660.1_CENPK1137D cds-NP_010639.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1132267-1133220:+ gene-YDR352W_EthanolRed rna-NM_001180660.1_EthanolRed cds-NP_010639.1_EthanolRed 98.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1135550-1136503:+ gene-YDR352W_FaliES1 rna-NM_001180660.1_FaliES1 cds-NP_010639.1_FaliES1 98.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000057.1:54569-55522:- gene-YDR352W_JAY291 rna-NM_001180660.1_JAY291 cds-NP_010639.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1141816-1142769:+ gene-YDR352W_MUCL30387 rna-NM_001180660.1_MUCL30387 cds-NP_010639.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1124422-1125375:+ gene-YDR352W_MUCL30388 rna-NM_001180660.1_MUCL30388 cds-NP_010639.1_MUCL30388 98.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1114116-1115069:+ gene-YDR352W_MUCL39482 rna-NM_001180660.1_MUCL39482 cds-NP_010639.1_MUCL39482 98.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1056050-1057003:+ gene-YDR352W_MUCL42920 rna-NM_001180660.1_MUCL42920 cds-NP_010639.1_MUCL42920 99.7 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1181724-1182677:+ gene-YDR352W_NCIM3186 rna-NM_001180660.1_NCIM3186 cds-NP_010639.1_NCIM3186 98.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1127789-1128742:+ gene-YDR352W_NCYC1407 rna-NM_001180660.1_NCYC1407 cds-NP_010639.1_NCYC1407 98.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1138216-1139169:+ gene-YDR352W_PE2H3 rna-NM_001180660.1_PE2H3 cds-NP_010639.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1143801-1144754:+ gene-YDR352W_PE2H4 rna-NM_001180660.1_PE2H4 cds-NP_010639.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1181801-1182754:+ gene-YDR352W_S288C rna-NM_001180660.1_S288C cds-NP_010639.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000072.1:6494-7447:+ gene-YDR352W_SA1 rna-NM_001180660.1_SA1 cds-NP_010639.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1139831-1140784:+ gene-YDR352W_ThermosaccDry rna-NM_001180660.1_ThermosaccDry cds-NP_010639.1_ThermosaccDry 98.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:567180-568133:+ gene-YDR352W_VR1 rna-NM_001180660.1_VR1 cds-NP_010639.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:182667-183620:+ gene-YDR352W_ZTW1 rna-NM_001180660.1_ZTW1 cds-NP_010639.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1133748-1134692:+ gene-YDR352W_Sparadoxus rna-NM_001180660.1_Sparadoxus cds-NP_010639.1_Sparadoxus 89.4 99.0 Verified 1 1 1 False True False False False

Additional files