YPK9 (YOR291W)


Gene profile

Gene name: YPK9
Reference locus (S288C): YOR291W
Gene biotype: protein_coding

Description: Vacuolar cation-transporting ATPase YPK9; Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily

Top 10 interactors (score): PCA1 (0.845); SMF2 (0.803); VPS35 (0.799); TDA4 (0.775); YPR114W (0.775); BET2 (0.772); ALG1 (0.768); SWF1 (0.757); CYR1 (0.743); YPT1 (0.701); OXR1 (0.682); APQ12 (0.682); SIF2 (0.682); GLO3 (0.68); SMF1 (0.669); INP53 (0.654); MCD1 (0.651); CCC1 (0.65); MIX17 (0.647); APC5 (0.621)

Homologues (species, bitscore): ATP13A3 (Homo sapiens, 713.8); Atp13a3 (Mus musculus, 723.8); atp13a2 (Danio rerio, 681.0); atp13a3 (Xenopus tropicalis, 654.4); CG32000 (Drosophila melanogaster, 621.7); catp-6 (Caenorhabditis elegans, 610.1); PDR2 (Arabidopsis thaliana, 300.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:851634-856052:+ gene-YOR291W_AKU4011 rna-NM_001183710.1_AKU4011 cds-NP_014934.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:253649-258064:+ gene-YOR291W_BG1 rna-NM_001183710.1_BG1 cds-NP_014934.1_BG1 99.4 99.9 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:837078-841496:+ gene-YOR291W_Bruggeman rna-NM_001183710.1_Bruggeman cds-NP_014934.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:837803-842221:+ gene-YOR291W_CAT1 rna-NM_001183710.1_CAT1 cds-NP_014934.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:835468-839886:+ gene-YOR291W_CBS1585 rna-NM_001183710.1_CBS1585 cds-NP_014934.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:833311-837729:+ gene-YOR291W_CBS436 rna-NM_001183710.1_CBS436 cds-NP_014934.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:831166-835584:+ gene-YOR291W_CBS6412 rna-NM_001183710.1_CBS6412 cds-NP_014934.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:840361-844779:+ gene-YOR291W_CBS6413 rna-NM_001183710.1_CBS6413 cds-NP_014934.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:860964-865382:+ gene-YOR291W_CENPK1137D rna-NM_001183710.1_CENPK1137D cds-NP_014934.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:827543-831961:+ gene-YOR291W_EthanolRed rna-NM_001183710.1_EthanolRed cds-NP_014934.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:833161-837579:+ gene-YOR291W_FaliES1 rna-NM_001183710.1_FaliES1 cds-NP_014934.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000078.1:165603-170021:- gene-YOR291W_JAY291 rna-NM_001183710.1_JAY291 cds-NP_014934.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:841320-845738:+ gene-YOR291W_MUCL30387 rna-NM_001183710.1_MUCL30387 cds-NP_014934.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:849305-853723:+ gene-YOR291W_MUCL30388 rna-NM_001183710.1_MUCL30388 cds-NP_014934.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:841996-846414:+ gene-YOR291W_MUCL39482 rna-NM_001183710.1_MUCL39482 cds-NP_014934.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:851494-855912:+ gene-YOR291W_MUCL42920 rna-NM_001183710.1_MUCL42920 cds-NP_014934.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:861064-865482:+ gene-YOR291W_NCIM3186 rna-NM_001183710.1_NCIM3186 cds-NP_014934.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:843009-847427:+ gene-YOR291W_NCYC1407 rna-NM_001183710.1_NCYC1407 cds-NP_014934.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:841299-845714:+ gene-YOR291W_PE2H3 rna-NM_001183710.1_PE2H3 cds-NP_014934.1_PE2H3 99.4 99.9 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:857646-862064:+ gene-YOR291W_PE2H4 rna-NM_001183710.1_PE2H4 cds-NP_014934.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:861175-865593:+ gene-YOR291W_S288C rna-NM_001183710.1_S288C cds-NP_014934.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:270861-275279:+ gene-YOR291W_SA1 rna-NM_001183710.1_SA1 cds-NP_014934.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:832344-836762:+ gene-YOR291W_ThermosaccDry rna-NM_001183710.1_ThermosaccDry cds-NP_014934.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:895740-900158:+ gene-YOR291W_VR1 rna-NM_001183710.1_VR1 cds-NP_014934.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:565232-569650:+ gene-YOR291W_ZTW1 rna-NM_001183710.1_ZTW1 cds-NP_014934.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:839148-843566:+ gene-YOR291W_Sparadoxus rna-NM_001183710.1_Sparadoxus cds-NP_014934.1_Sparadoxus 90.0 99.9 Verified 1 1 1 False True False False False

Additional files