YPK3 (YBR028C)


Gene profile

Gene name: YPK3
Reference locus (S288C): YBR028C
Gene biotype: protein_coding

Description: Serine/threonine-protein kinase YPK3; AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation

Top 10 interactors (score): RPS6B (0.987); TOR1 (0.968); TIF4632 (0.961); TIF4631 (0.961); TOR2 (0.945); KOG1 (0.935); SCH9 (0.924); YPK1 (0.91); LST8 (0.845); RPS6A (0.829); GTR2 (0.809); TSC11 (0.804); GTR1 (0.801); CDC33 (0.77); RHB1 (0.755); PKH1 (0.74); TIF3 (0.731); AVO1 (0.727); PKH3 (0.724); PKH2 (0.719)

Homologues (species, bitscore): RPS6KB1 (Homo sapiens, 246.9); Rps6kb1 (Mus musculus, 246.9); rps6kb1b (Danio rerio, 243.8); rps6kb1 (Xenopus tropicalis, 243.0); S6k (Drosophila melanogaster, 219.5); rsks-1 (Caenorhabditis elegans, 218.8); S6K2 (Arabidopsis thaliana, 220.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:276861-278438:- gene-YBR028C_AKU4011 rna-NM_001178376.1_AKU4011 cds-NP_009584.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:267009-268586:- gene-YBR028C_BG1 rna-NM_001178376.1_BG1 cds-NP_009584.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:480278-481855:- gene-YBR028C_Bruggeman rna-NM_001178376.1_Bruggeman cds-NP_009584.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:281024-282601:- gene-YBR028C_CAT1 rna-NM_001178376.1_CAT1 cds-NP_009584.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:268898-270475:- gene-YBR028C_CBS1585 rna-NM_001178376.1_CBS1585 cds-NP_009584.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:277158-278735:- gene-YBR028C_CBS436 rna-NM_001178376.1_CBS436 cds-NP_009584.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:367402-368979:- gene-YBR028C_CBS6412 rna-NM_001178376.1_CBS6412 cds-NP_009584.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:274266-275843:- gene-YBR028C_CBS6413 rna-NM_001178376.1_CBS6413 cds-NP_009584.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:288175-289752:- gene-YBR028C_CENPK1137D rna-NM_001178376.1_CENPK1137D cds-NP_009584.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:403874-405451:- gene-YBR028C_EthanolRed rna-NM_001178376.1_EthanolRed cds-NP_009584.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:291969-293546:- gene-YBR028C_FaliES1 rna-NM_001178376.1_FaliES1 cds-NP_009584.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000048.1:4052-5629:+ gene-YBR028C_JAY291 rna-NM_001178376.1_JAY291 cds-NP_009584.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:278187-279764:- gene-YBR028C_MUCL30387 rna-NM_001178376.1_MUCL30387 cds-NP_009584.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:278442-280019:- gene-YBR028C_MUCL30388 rna-NM_001178376.1_MUCL30388 cds-NP_009584.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:268880-270457:- gene-YBR028C_MUCL39482 rna-NM_001178376.1_MUCL39482 cds-NP_009584.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:276330-277907:- gene-YBR028C_MUCL42920 rna-NM_001178376.1_MUCL42920 cds-NP_009584.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:294222-295799:- gene-YBR028C_NCIM3186 rna-NM_001178376.1_NCIM3186 cds-NP_009584.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:270057-271634:- gene-YBR028C_NCYC1407 rna-NM_001178376.1_NCYC1407 cds-NP_009584.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:282234-283811:- gene-YBR028C_PE2H3 rna-NM_001178376.1_PE2H3 cds-NP_009584.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:279902-281479:- gene-YBR028C_PE2H4 rna-NM_001178376.1_PE2H4 cds-NP_009584.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:294425-296002:- gene-YBR028C_S288C rna-NM_001178376.1_S288C cds-NP_009584.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000037.1:12701-14278:+ gene-YBR028C_SA1 rna-NM_001178376.1_SA1 cds-NP_009584.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:291677-293254:- gene-YBR028C_ThermosaccDry rna-NM_001178376.1_ThermosaccDry cds-NP_009584.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:273586-275163:- gene-YBR028C_VR1 rna-NM_001178376.1_VR1 cds-NP_009584.1_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:267657-269234:- gene-YBR028C_ZTW1 rna-NM_001178376.1_ZTW1 cds-NP_009584.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:303883-305460:- gene-YBR028C_Sparadoxus rna-NM_001178376.1_Sparadoxus cds-NP_009584.1_Sparadoxus 89.3 100.0 Verified 1 1 1 False True False False False

Additional files