Gene name: YPK2
Reference locus (S288C): YMR104C
Gene biotype: protein_coding
Description: Serine/threonine-protein kinase YPK2/YKR2; Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily
Top 10 interactors (score): AVO1 (0.998); TOR2 (0.996); TSC11 (0.966); YMR103C (0.955); TOR1 (0.945); LST8 (0.926); KOG1 (0.923); TIF4631 (0.914); TIF4632 (0.914); RHO1 (0.878); PKH1 (0.854); ORM2 (0.82); ORM1 (0.815); YPK1 (0.809); SLM1 (0.796); PKH2 (0.794); SPF1 (0.788); RPS6B (0.763); AVO2 (0.763); RPS6A (0.763)
Homologues (species, bitscore): SGK2 (Homo sapiens, 331.3); Sgk2 (Mus musculus, 327.0); sgk1 (Danio rerio, 327.8); sgk1 (Xenopus tropicalis, 327.4); Akt1 (Drosophila melanogaster, 316.2); sgk-1 (Caenorhabditis elegans, 333.6); S6K2 (Arabidopsis thaliana, 303.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:511363-513396:- | gene-YMR104C_AKU4011 | rna-NM_001182604.1_AKU4011 | cds-NP_013822.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:29619-31652:+ | gene-YMR104C_BG1 | rna-NM_001182604.1_BG1 | cds-NP_013822.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:453790-455823:- | gene-YMR104C_Bruggeman | rna-NM_001182604.1_Bruggeman | cds-NP_013822.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:454111-456144:- | gene-YMR104C_CAT1 | rna-NM_001182604.1_CAT1 | cds-NP_013822.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:444310-446343:- | gene-YMR104C_CBS1585 | rna-NM_001182604.1_CBS1585 | cds-NP_013822.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:449625-451658:- | gene-YMR104C_CBS436 | rna-NM_001182604.1_CBS436 | cds-NP_013822.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:557404-559437:- | gene-YMR104C_CBS6412 | rna-NM_001182604.1_CBS6412 | cds-NP_013822.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:443567-445600:- | gene-YMR104C_CBS6413 | rna-NM_001182604.1_CBS6413 | cds-NP_013822.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:467527-469560:- | gene-YMR104C_CENPK1137D | rna-NM_001182604.1_CENPK1137D | cds-NP_013822.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:444194-446227:- | gene-YMR104C_EthanolRed | rna-NM_001182604.1_EthanolRed | cds-NP_013822.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:447367-449400:- | gene-YMR104C_FaliES1 | rna-NM_001182604.1_FaliES1 | cds-NP_013822.1_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000349.1:10173-12206:- | gene-YMR104C_JAY291 | rna-NM_001182604.1_JAY291 | cds-NP_013822.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:450712-452745:- | gene-YMR104C_MUCL30387 | rna-NM_001182604.1_MUCL30387 | cds-NP_013822.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:454701-456734:- | gene-YMR104C_MUCL30388 | rna-NM_001182604.1_MUCL30388 | cds-NP_013822.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:444616-446649:- | gene-YMR104C_MUCL39482 | rna-NM_001182604.1_MUCL39482 | cds-NP_013822.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:451277-453310:- | gene-YMR104C_MUCL42920 | rna-NM_001182604.1_MUCL42920 | cds-NP_013822.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:473374-475407:- | gene-YMR104C_NCIM3186 | rna-NM_001182604.1_NCIM3186 | cds-NP_013822.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:444511-446544:- | gene-YMR104C_NCYC1407 | rna-NM_001182604.1_NCYC1407 | cds-NP_013822.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:450223-452256:- | gene-YMR104C_PE2H3 | rna-NM_001182604.1_PE2H3 | cds-NP_013822.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:456318-458351:- | gene-YMR104C_PE2H4 | rna-NM_001182604.1_PE2H4 | cds-NP_013822.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:473420-475453:- | gene-YMR104C_S288C | rna-NM_001182604.1_S288C | cds-NP_013822.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:74713-76746:+ | gene-YMR104C_SA1 | rna-NM_001182604.1_SA1 | cds-NP_013822.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:445161-447194:- | gene-YMR104C_ThermosaccDry | rna-NM_001182604.1_ThermosaccDry | cds-NP_013822.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:456809-458842:- | gene-YMR104C_VR1 | rna-NM_001182604.1_VR1 | cds-NP_013822.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:421441-423474:- | gene-YMR104C_ZTW1 | rna-NM_001182604.1_ZTW1 | cds-NP_013822.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:457676-459709:- | gene-YMR104C_Sparadoxus | rna-NM_001182604.1_Sparadoxus | cds-NP_013822.1_Sparadoxus | 89.2 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |