YPC1 (YBR183W)


Gene profile

Gene name: YPC1
Reference locus (S288C): YBR183W
Gene biotype: protein_coding

Description: Alkaline ceramidase; also has reverse (CoA-independent) ceramide synthase activity; catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance; YPC1 has a paralog, YDC1, that arose from the whole genome duplication

Top 10 interactors (score): ISC1 (0.992); LAC1 (0.989); LAG1 (0.988); LCB5 (0.985); LCB4 (0.98); SUR2 (0.973); LCB1 (0.919); PIC2 (0.916); YSR3 (0.896); DPL1 (0.894); LCB2 (0.892); AUR1 (0.813); LCB3 (0.786); LIP1 (0.717); TDA4 (0.716); YPR114W (0.716); IPT1 (0.716); ORM1 (0.699); SCH9 (0.676); KEI1 (0.651)

Homologues (species, bitscore): ACER3 (Homo sapiens, 145.2); Acer3 (Mus musculus, 149.1); LOC555411 (Danio rerio, 149.8); acer3 (Xenopus tropicalis, 152.5); bwa (Drosophila melanogaster, 51.6); ATCES1 (Arabidopsis thaliana, 75.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:579484-580434:+ gene-YBR183W_AKU4011 rna-NM_001178531.1_AKU4011 cds-NP_009742.1_AKU4011 99.6 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:569465-570415:+ gene-YBR183W_BG1 rna-NM_001178531.1_BG1 cds-NP_009742.1_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:385344-386294:+ gene-YBR183W_Bruggeman rna-NM_001178531.1_Bruggeman cds-NP_009742.1_Bruggeman 99.5 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:584750-585700:+ gene-YBR183W_CAT1 rna-NM_001178531.1_CAT1 cds-NP_009742.1_CAT1 99.5 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:571265-572215:+ gene-YBR183W_CBS1585 rna-NM_001178531.1_CBS1585 cds-NP_009742.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:578817-579767:+ gene-YBR183W_CBS436 rna-NM_001178531.1_CBS436 cds-NP_009742.1_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:667873-668823:+ gene-YBR183W_CBS6412 rna-NM_001178531.1_CBS6412 cds-NP_009742.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:577070-578020:+ gene-YBR183W_CBS6413 rna-NM_001178531.1_CBS6413 cds-NP_009742.1_CBS6413 99.6 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:589889-590839:+ gene-YBR183W_CENPK1137D rna-NM_001178531.1_CENPK1137D cds-NP_009742.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:704641-705591:+ gene-YBR183W_EthanolRed rna-NM_001178531.1_EthanolRed cds-NP_009742.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:595552-596502:+ gene-YBR183W_FaliES1 rna-NM_001178531.1_FaliES1 cds-NP_009742.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000104.1:9741-10691:- gene-YBR183W_JAY291 rna-NM_001178531.1_JAY291 cds-NP_009742.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:584025-584975:+ gene-YBR183W_MUCL30387 rna-NM_001178531.1_MUCL30387 cds-NP_009742.1_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:601100-602050:+ gene-YBR183W_MUCL30388 rna-NM_001178531.1_MUCL30388 cds-NP_009742.1_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:569638-570588:+ gene-YBR183W_MUCL39482 rna-NM_001178531.1_MUCL39482 cds-NP_009742.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:579060-580010:+ gene-YBR183W_MUCL42920 rna-NM_001178531.1_MUCL42920 cds-NP_009742.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:595912-596862:+ gene-YBR183W_NCIM3186 rna-NM_001178531.1_NCIM3186 cds-NP_009742.1_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:571746-572696:+ gene-YBR183W_NCYC1407 rna-NM_001178531.1_NCYC1407 cds-NP_009742.1_NCYC1407 99.6 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:584337-585287:+ gene-YBR183W_PE2H3 rna-NM_001178531.1_PE2H3 cds-NP_009742.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:582013-582963:+ gene-YBR183W_PE2H4 rna-NM_001178531.1_PE2H4 cds-NP_009742.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:596115-597065:+ gene-YBR183W_S288C rna-NM_001178531.1_S288C cds-NP_009742.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000080.1:3812-4762:+ gene-YBR183W_SA1 rna-NM_001178531.1_SA1 cds-NP_009742.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:594562-595512:+ gene-YBR183W_ThermosaccDry rna-NM_001178531.1_ThermosaccDry cds-NP_009742.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:575737-576687:+ gene-YBR183W_VR1 rna-NM_001178531.1_VR1 cds-NP_009742.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:569180-570130:+ gene-YBR183W_ZTW1 rna-NM_001178531.1_ZTW1 cds-NP_009742.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:610944-611894:+ gene-YBR183W_Sparadoxus rna-NM_001178531.1_Sparadoxus cds-NP_009742.1_Sparadoxus 90.3 100.0 Verified 1 1 1 False True False False False

Additional files