YOX1 (YML027W)


Gene profile

Gene name: YOX1
Reference locus (S288C): YML027W
Gene biotype: protein_coding

Description: Homeobox protein YOX1; Homeobox transcriptional repressor; binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; phosphorylated by Cdc28p; relocalizes from nucleus to cytoplasm upon DNA replication stress; YOX1 has a paralog, YHP1, that arose from the whole genome duplication

Top 10 interactors (score): MCM1 (0.999); PCL1 (0.95); FKH2 (0.942); HCM1 (0.935); YHP1 (0.934); CDC28 (0.929); CLN1 (0.887); CLB6 (0.874); MBP1 (0.872); FKH1 (0.855); NDD1 (0.849); SWI4 (0.841); SWI6 (0.819); TOS4 (0.809); NRM1 (0.8); SWI5 (0.786); RNR1 (0.767); STB1 (0.76); WHI5 (0.748); ACE2 (0.747)

Homologues (species, bitscore): POU3F3 (Homo sapiens, 54.7); Pou3f3 (Mus musculus, 54.7); pou3f3b (Danio rerio, 54.7); pou5f3.2 (Xenopus tropicalis, 55.8); CG4328 (Drosophila melanogaster, 56.6); php-3 (Caenorhabditis elegans, 55.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:271000-272157:+ gene-YML027W_AKU4011 rna-NM_001182385.1_AKU4011 cds-NP_013685.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:270716-271873:- gene-YML027W_BG1 rna-NM_001182385.1_BG1 cds-NP_013685.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:210952-212109:+ gene-YML027W_Bruggeman rna-NM_001182385.1_Bruggeman cds-NP_013685.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:213465-214622:+ gene-YML027W_CAT1 rna-NM_001182385.1_CAT1 cds-NP_013685.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:203949-205106:+ gene-YML027W_CBS1585 rna-NM_001182385.1_CBS1585 cds-NP_013685.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:209485-210642:+ gene-YML027W_CBS436 rna-NM_001182385.1_CBS436 cds-NP_013685.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:317686-318843:+ gene-YML027W_CBS6412 rna-NM_001182385.1_CBS6412 cds-NP_013685.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:203207-204364:+ gene-YML027W_CBS6413 rna-NM_001182385.1_CBS6413 cds-NP_013685.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:215927-217084:+ gene-YML027W_CENPK1137D rna-NM_001182385.1_CENPK1137D cds-NP_013685.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:203974-205131:+ gene-YML027W_EthanolRed rna-NM_001182385.1_EthanolRed cds-NP_013685.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:206938-208095:+ gene-YML027W_FaliES1 rna-NM_001182385.1_FaliES1 cds-NP_013685.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000237.1:4042-5199:- gene-YML027W_JAY291 rna-NM_001182385.1_JAY291 cds-NP_013685.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:208684-209841:+ gene-YML027W_MUCL30387 rna-NM_001182385.1_MUCL30387 cds-NP_013685.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:212661-213818:+ gene-YML027W_MUCL30388 rna-NM_001182385.1_MUCL30388 cds-NP_013685.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:204235-205392:+ gene-YML027W_MUCL39482 rna-NM_001182385.1_MUCL39482 cds-NP_013685.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:209790-210947:+ gene-YML027W_MUCL42920 rna-NM_001182385.1_MUCL42920 cds-NP_013685.1_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:221360-222517:+ gene-YML027W_NCIM3186 rna-NM_001182385.1_NCIM3186 cds-NP_013685.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:204176-205333:+ gene-YML027W_NCYC1407 rna-NM_001182385.1_NCYC1407 cds-NP_013685.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:210076-211233:+ gene-YML027W_PE2H3 rna-NM_001182385.1_PE2H3 cds-NP_013685.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:216171-217328:+ gene-YML027W_PE2H4 rna-NM_001182385.1_PE2H4 cds-NP_013685.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:221406-222563:+ gene-YML027W_S288C rna-NM_001182385.1_S288C cds-NP_013685.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000088.1:16288-17445:- gene-YML027W_SA1 rna-NM_001182385.1_SA1 cds-NP_013685.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:204011-205168:+ gene-YML027W_ThermosaccDry rna-NM_001182385.1_ThermosaccDry cds-NP_013685.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:208017-209174:+ gene-YML027W_VR1 rna-NM_001182385.1_VR1 cds-NP_013685.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:183066-184223:+ gene-YML027W_ZTW1 rna-NM_001182385.1_ZTW1 cds-NP_013685.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:214787-215941:+ gene-YML027W_Sparadoxus rna-NM_001182385.1_Sparadoxus cds-NP_013685.1_Sparadoxus 90.6 99.7 Verified 1 1 1 False True False False False

Additional files