Gene name: YOS9
Reference locus (S288C): YDR057W
Gene biotype: protein_coding
Description: Protein OS-9 homolog; ER quality-control lectin; integral subunit of the HRD ligase; participates in efficient ER retention of misfolded proteins by recognizing them and delivering them to Hrd1p; binds to glycans with terminal alpha-1,6 linked mannose on misfolded N-glycosylated proteins and participates in targeting proteins to ERAD; member of the OS-9 protein family
Top 10 interactors (score): HRD3 (0.999); DER1 (0.999); HRD1 (0.999); CDC48 (0.999); USA1 (0.999); UBX2 (0.999); KAR2 (0.999); MNL1 (0.997); NPL4 (0.973); UBC7 (0.963); CNE1 (0.961); PRC1 (0.961); SSM4 (0.955); MNS1 (0.927); KRE5 (0.925); DFM1 (0.923); LHS1 (0.921); UFD1 (0.916); CDC34 (0.911); PDI1 (0.904)
Homologues (species, bitscore): OS9 (Homo sapiens, 50.8); Erlec1 (Mus musculus, 53.5); erlec1 (Danio rerio, 51.2); CG6766 (Drosophila melanogaster, 53.9); Y105E8A.2 (Caenorhabditis elegans, 53.9); OS9 (Arabidopsis thaliana, 59.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:543470-545098:+ | gene-YDR057W_AKU4011 | rna-NM_001180365.3_AKU4011 | cds-NP_010342.3_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:10117-11745:- | gene-YDR057W_BG1 | rna-NM_001180365.3_BG1 | cds-NP_010342.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:575808-577405:+ | gene-YDR057W_Bruggeman | rna-NM_001180365.3_Bruggeman | cds-NP_010342.3_Bruggeman | 97.8 | 98.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:558808-560436:+ | gene-YDR057W_CAT1 | rna-NM_001180365.3_CAT1 | cds-NP_010342.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:534424-536052:+ | gene-YDR057W_CBS1585 | rna-NM_001180365.3_CBS1585 | cds-NP_010342.3_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:559590-561218:+ | gene-YDR057W_CBS436 | rna-NM_001180365.3_CBS436 | cds-NP_010342.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:530836-532464:+ | gene-YDR057W_CBS6412 | rna-NM_001180365.3_CBS6412 | cds-NP_010342.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:559505-561133:+ | gene-YDR057W_CBS6413 | rna-NM_001180365.3_CBS6413 | cds-NP_010342.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:564894-566522:+ | gene-YDR057W_CENPK1137D | rna-NM_001180365.3_CENPK1137D | cds-NP_010342.3_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:545294-546922:+ | gene-YDR057W_EthanolRed | rna-NM_001180365.3_EthanolRed | cds-NP_010342.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:551734-553362:+ | gene-YDR057W_FaliES1 | rna-NM_001180365.3_FaliES1 | cds-NP_010342.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000246.1:1352-2980:- | gene-YDR057W_JAY291 | rna-NM_001180365.3_JAY291 | cds-NP_010342.3_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:560470-562098:+ | gene-YDR057W_MUCL30387 | rna-NM_001180365.3_MUCL30387 | cds-NP_010342.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:550891-552488:+ | gene-YDR057W_MUCL30388 | rna-NM_001180365.3_MUCL30388 | cds-NP_010342.3_MUCL30388 | 97.8 | 98.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:535795-537423:+ | gene-YDR057W_MUCL39482 | rna-NM_001180365.3_MUCL39482 | cds-NP_010342.3_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:466270-467898:+ | gene-YDR057W_MUCL42920 | rna-NM_001180365.3_MUCL42920 | cds-NP_010342.3_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:565850-567478:+ | gene-YDR057W_NCIM3186 | rna-NM_001180365.3_NCIM3186 | cds-NP_010342.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:534729-536357:+ | gene-YDR057W_NCYC1407 | rna-NM_001180365.3_NCYC1407 | cds-NP_010342.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:554366-555994:+ | gene-YDR057W_PE2H3 | rna-NM_001180365.3_PE2H3 | cds-NP_010342.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:553671-555299:+ | gene-YDR057W_PE2H4 | rna-NM_001180365.3_PE2H4 | cds-NP_010342.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:565927-567555:+ | gene-YDR057W_S288C | rna-NM_001180365.3_S288C | cds-NP_010342.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:77936-79564:- | gene-YDR057W_SA1 | rna-NM_001180365.3_SA1 | cds-NP_010342.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:551474-553102:+ | gene-YDR057W_ThermosaccDry | rna-NM_001180365.3_ThermosaccDry | cds-NP_010342.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:564180-565808:+ | gene-YDR057W_VR1 | rna-NM_001180365.3_VR1 | cds-NP_010342.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:549079-550707:+ | gene-YDR057W_ZTW1 | rna-NM_001180365.3_ZTW1 | cds-NP_010342.3_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:553498-555131:+ | gene-YDR057W_Sparadoxus | rna-NM_001180365.3_Sparadoxus | cds-NP_010342.3_Sparadoxus | 83.4 | 97.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |