Gene name: YOP1
Reference locus (S288C): YPR028W
Gene biotype: protein_coding
Description: Receptor expression-enhancing protein 5/6; Protein YOP1; Reticulon-interacting protein; ER integral membrane protein involved in the generation of tubular ER morphology; promotes membrane curvature; forms tubules in vitro; regulates the ER asymmetry-induced inheritance block during ER stress; role in ER-derived peroxisomal biogenesis; interacts with Yip1p to mediate membrane traffic and with Sey1p to maintain ER morphology; facilitates lipid exchange between the ER and mitochondria; forms ER foci upon DNA replication stress
Top 10 interactors (score): SEY1 (0.997); RTN1 (0.995); RTN2 (0.972); POM33 (0.939); LNP1 (0.926); POM152 (0.881); YIP1 (0.878); SCS2 (0.867); BRR6 (0.861); NDC1 (0.85); SEC13 (0.845); SBH1 (0.841); PEX30 (0.838); PEX31 (0.836); SEC63 (0.82); POM34 (0.812); SBH2 (0.77); APQ12 (0.761); ADE6 (0.76); SEC23 (0.754)
Homologues (species, bitscore): REEP5 (Homo sapiens, 102.8); Reep5 (Mus musculus, 103.6); Reep6 (Danio rerio, 96.3); reep5 (Xenopus tropicalis, 99.4); CG8331 (Drosophila melanogaster, 95.9); yop-1 (Caenorhabditis elegans, 112.1); HVA22D (Arabidopsis thaliana, 67.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:595154-595829:+ | gene-YPR028W_AKU4011 | rna-NM_001184125.1_AKU4011 | cds-NP_015353.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:301804-302479:- | gene-YPR028W_BG1 | rna-NM_001184125.1_BG1 | cds-NP_015353.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:672815-673490:+ | gene-YPR028W_Bruggeman | rna-NM_001184125.1_Bruggeman | cds-NP_015353.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:715815-716490:+ | gene-YPR028W_CAT1 | rna-NM_001184125.1_CAT1 | cds-NP_015353.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:598838-599513:+ | gene-YPR028W_CBS1585 | rna-NM_001184125.1_CBS1585 | cds-NP_015353.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:613235-613910:+ | gene-YPR028W_CBS436 | rna-NM_001184125.1_CBS436 | cds-NP_015353.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:602586-603261:+ | gene-YPR028W_CBS6412 | rna-NM_001184125.1_CBS6412 | cds-NP_015353.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:595784-596460:+ | gene-YPR028W_CBS6413 | rna-NM_001184125.1_CBS6413 | cds-NP_015353.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:623504-624179:+ | gene-YPR028W_CENPK1137D | rna-NM_001184125.1_CENPK1137D | cds-NP_015353.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:593084-593759:+ | gene-YPR028W_EthanolRed | rna-NM_001184125.1_EthanolRed | cds-NP_015353.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:600887-601562:+ | gene-YPR028W_FaliES1 | rna-NM_001184125.1_FaliES1 | cds-NP_015353.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000116.1:26323-26998:- | gene-YPR028W_JAY291 | rna-NM_001184125.1_JAY291 | cds-NP_015353.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:614028-614703:+ | gene-YPR028W_MUCL30387 | rna-NM_001184125.1_MUCL30387 | cds-NP_015353.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:612708-613383:+ | gene-YPR028W_MUCL30388 | rna-NM_001184125.1_MUCL30388 | cds-NP_015353.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:592095-592770:+ | gene-YPR028W_MUCL39482 | rna-NM_001184125.1_MUCL39482 | cds-NP_015353.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:654902-655577:+ | gene-YPR028W_MUCL42920 | rna-NM_001184125.1_MUCL42920 | cds-NP_015353.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:623510-624185:+ | gene-YPR028W_NCIM3186 | rna-NM_001184125.1_NCIM3186 | cds-NP_015353.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:600026-600701:+ | gene-YPR028W_NCYC1407 | rna-NM_001184125.1_NCYC1407 | cds-NP_015353.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:606287-606962:+ | gene-YPR028W_PE2H3 | rna-NM_001184125.1_PE2H3 | cds-NP_015353.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:605935-606610:+ | gene-YPR028W_PE2H4 | rna-NM_001184125.1_PE2H4 | cds-NP_015353.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:623527-624202:+ | gene-YPR028W_S288C | rna-NM_001184125.1_S288C | cds-NP_015353.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:76573-77248:- | gene-YPR028W_SA1 | rna-NM_001184125.1_SA1 | cds-NP_015353.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:600687-601362:+ | gene-YPR028W_ThermosaccDry | rna-NM_001184125.1_ThermosaccDry | cds-NP_015353.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:616948-617623:+ | gene-YPR028W_VR1 | rna-NM_001184125.1_VR1 | cds-NP_015353.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:600008-600683:+ | gene-YPR028W_ZTW1 | rna-NM_001184125.1_ZTW1 | cds-NP_015353.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:600832-601511:+ | gene-YPR028W_Sparadoxus | rna-NM_001184125.1_Sparadoxus | cds-NP_015353.1_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |