Gene name: YNL134C
Reference locus (S288C): YNL134C
Gene biotype: protein_coding
Description: Uncharacterized protein YNL134C; NADH-dependent aldehyde reductase, involved in detoxification of furfural; expression is up-regulated in the presence of furfural and 5-hydroxymethylfurfural, which are compounds generated during lignocellulosic biomass pre-treatment; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): HSP31 (0.942); YDL124W (0.93); YML131W (0.865); GRE2 (0.829); ADH6 (0.81); ETR1 (0.778); YJR096W (0.777); ADH7 (0.756); ECM4 (0.675); TPS1 (0.672); HSP104 (0.671); MSC1 (0.669); NTH1 (0.642); YMR090W (0.639); NTH2 (0.621); AST1 (0.602); FYV6 (0.564); AST2 (0.546); ZWF1 (0.536); DCS2 (0.531)
Homologues (species, bitscore): TP53I3 (Danio rerio, 58.9); tp53i3 (Xenopus tropicalis, 58.9); rad-8 (Caenorhabditis elegans, 56.2); AOR (Arabidopsis thaliana, 82.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:366135-367265:- | gene-YNL134C_AKU4011 | rna-NM_001182972.3_AKU4011 | cds-NP_014265.3_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:270128-271258:- | gene-YNL134C_BG1 | rna-NM_001182972.3_BG1 | cds-NP_014265.3_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:376234-377364:- | gene-YNL134C_Bruggeman | rna-NM_001182972.3_Bruggeman | cds-NP_014265.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:419429-420559:- | gene-YNL134C_CAT1 | rna-NM_001182972.3_CAT1 | cds-NP_014265.3_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:366755-367885:- | gene-YNL134C_CBS1585 | rna-NM_001182972.3_CBS1585 | cds-NP_014265.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:435150-436280:- | gene-YNL134C_CBS436 | rna-NM_001182972.3_CBS436 | cds-NP_014265.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:362209-363339:- | gene-YNL134C_CBS6412 | rna-NM_001182972.3_CBS6412 | cds-NP_014265.3_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:363173-364303:- | gene-YNL134C_CBS6413 | rna-NM_001182972.3_CBS6413 | cds-NP_014265.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:366303-367432:- | gene-YNL134C_CENPK1137D | rna-NM_001182972.3_CENPK1137D | cds-NP_014265.3_CENPK1137D | 99.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:363127-364257:- | gene-YNL134C_EthanolRed | rna-NM_001182972.3_EthanolRed | cds-NP_014265.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:359029-360159:- | gene-YNL134C_FaliES1 | rna-NM_001182972.3_FaliES1 | cds-NP_014265.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000021.1:15409-16539:- | gene-YNL134C_JAY291 | rna-NM_001182972.3_JAY291 | cds-NP_014265.3_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:372249-373379:- | gene-YNL134C_MUCL30387 | rna-NM_001182972.3_MUCL30387 | cds-NP_014265.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:407366-408496:- | gene-YNL134C_MUCL30388 | rna-NM_001182972.3_MUCL30388 | cds-NP_014265.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:364035-365165:- | gene-YNL134C_MUCL39482 | rna-NM_001182972.3_MUCL39482 | cds-NP_014265.3_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:367030-368160:- | gene-YNL134C_MUCL42920 | rna-NM_001182972.3_MUCL42920 | cds-NP_014265.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:372420-373550:- | gene-YNL134C_NCIM3186 | rna-NM_001182972.3_NCIM3186 | cds-NP_014265.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:366167-367297:- | gene-YNL134C_NCYC1407 | rna-NM_001182972.3_NCYC1407 | cds-NP_014265.3_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:365153-366283:- | gene-YNL134C_PE2H3 | rna-NM_001182972.3_PE2H3 | cds-NP_014265.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:364541-365671:- | gene-YNL134C_PE2H4 | rna-NM_001182972.3_PE2H4 | cds-NP_014265.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:372451-373581:- | gene-YNL134C_S288C | rna-NM_001182972.3_S288C | cds-NP_014265.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:39932-41062:+ | gene-YNL134C_SA1 | rna-NM_001182972.3_SA1 | cds-NP_014265.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:359883-361013:- | gene-YNL134C_ThermosaccDry | rna-NM_001182972.3_ThermosaccDry | cds-NP_014265.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:378546-379676:- | gene-YNL134C_VR1 | rna-NM_001182972.3_VR1 | cds-NP_014265.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:269716-270846:- | gene-YNL134C_ZTW1 | rna-NM_001182972.3_ZTW1 | cds-NP_014265.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:370676-371806:- | gene-YNL134C_Sparadoxus | rna-NM_001182972.3_Sparadoxus | cds-NP_014265.3_Sparadoxus | 89.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |