YML018C (YML018C)


Gene profile

Gene name: YML018C
Reference locus (S288C): YML018C
Gene biotype: protein_coding

Description: Uncharacterized vacuolar membrane protein YML018C; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; physical interaction with Atg27p suggests a possible role in autophagy; YML018C is not an essential gene; relative distribution to the vacuolar membrane decreases upon DNA replication stress; YML018C has a paralog, THI74, that arose from the whole genome duplication; Belongs to the TPT transporter family

Top 10 interactors (score): YHR112C (0.865); AIM9 (0.78); FMP42 (0.75); VBA4 (0.718); RET3 (0.702); MXR1 (0.657); SEC26 (0.656); GAR1 (0.594); SAP4 (0.593); RET2 (0.578); HO (0.568); SNF8 (0.561); GOS1 (0.561); LEU5 (0.508); MTW1 (0.497); COT1 (0.492); PEP7 (0.482); LAT1 (0.464); MET10 (0.458); IDH1 (0.455)

Homologues (species, bitscore): SLC35F5 (Homo sapiens, 166.8); Slc35f5 (Mus musculus, 167.9); slc35f5 (Xenopus tropicalis, 95.9); CG8195 (Drosophila melanogaster, 146.4); B0041.5 (Caenorhabditis elegans, 105.1); AT4G32140 (Arabidopsis thaliana, 181.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:284363-285544:- gene-YML018C_AKU4011 rna-NM_001182376.1_AKU4011 cds-NP_013694.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:257322-258503:+ gene-YML018C_BG1 rna-NM_001182376.1_BG1 cds-NP_013694.1_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:224325-225506:- gene-YML018C_Bruggeman rna-NM_001182376.1_Bruggeman cds-NP_013694.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:226835-228016:- gene-YML018C_CAT1 rna-NM_001182376.1_CAT1 cds-NP_013694.1_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:217313-218494:- gene-YML018C_CBS1585 rna-NM_001182376.1_CBS1585 cds-NP_013694.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:222855-224036:- gene-YML018C_CBS436 rna-NM_001182376.1_CBS436 cds-NP_013694.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:331050-332231:- gene-YML018C_CBS6412 rna-NM_001182376.1_CBS6412 cds-NP_013694.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:216570-217751:- gene-YML018C_CBS6413 rna-NM_001182376.1_CBS6413 cds-NP_013694.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:229292-230473:- gene-YML018C_CENPK1137D rna-NM_001182376.1_CENPK1137D cds-NP_013694.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:217337-218518:- gene-YML018C_EthanolRed rna-NM_001182376.1_EthanolRed cds-NP_013694.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:220301-221482:- gene-YML018C_FaliES1 rna-NM_001182376.1_FaliES1 cds-NP_013694.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:215427-216608:+ gene-YML018C_JAY291 rna-NM_001182376.1_JAY291 cds-NP_013694.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:222055-223236:- gene-YML018C_MUCL30387 rna-NM_001182376.1_MUCL30387 cds-NP_013694.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:226724-227905:- gene-YML018C_MUCL30388 rna-NM_001182376.1_MUCL30388 cds-NP_013694.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:217598-218779:- gene-YML018C_MUCL39482 rna-NM_001182376.1_MUCL39482 cds-NP_013694.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:223162-224343:- gene-YML018C_MUCL42920 rna-NM_001182376.1_MUCL42920 cds-NP_013694.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:234725-235906:- gene-YML018C_NCIM3186 rna-NM_001182376.1_NCIM3186 cds-NP_013694.1_NCIM3186 98.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:217539-218720:- gene-YML018C_NCYC1407 rna-NM_001182376.1_NCYC1407 cds-NP_013694.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:223446-224627:- gene-YML018C_PE2H3 rna-NM_001182376.1_PE2H3 cds-NP_013694.1_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:229541-230722:- gene-YML018C_PE2H4 rna-NM_001182376.1_PE2H4 cds-NP_013694.1_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:234771-235952:- gene-YML018C_S288C rna-NM_001182376.1_S288C cds-NP_013694.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000088.1:2894-4075:+ gene-YML018C_SA1 rna-NM_001182376.1_SA1 cds-NP_013694.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:217374-218555:- gene-YML018C_ThermosaccDry rna-NM_001182376.1_ThermosaccDry cds-NP_013694.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:221387-222568:- gene-YML018C_VR1 rna-NM_001182376.1_VR1 cds-NP_013694.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:196428-197609:- gene-YML018C_ZTW1 rna-NM_001182376.1_ZTW1 cds-NP_013694.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:228126-229307:- gene-YML018C_Sparadoxus rna-NM_001182376.1_Sparadoxus cds-NP_013694.1_Sparadoxus 90.5 99.9 Verified 1 1 1 False True False False False

Additional files