Gene name: YME1
Reference locus (S288C): YPR024W
Gene biotype: protein_coding
Description: Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant; In the C-terminal section; belongs to the peptidase M41 family
Top 10 interactors (score): YME2 (0.994); MGR1 (0.993); MGR3 (0.989); OMA1 (0.975); PIM1 (0.973); ATG32 (0.965); ATP1 (0.957); TIM9 (0.939); PHB1 (0.936); PHB2 (0.932); TIM10 (0.91); MCX1 (0.909); PCP1 (0.906); OXA1 (0.893); HSP60 (0.857); ATP23 (0.855); TIM23 (0.848); MIC60 (0.839); TIM17 (0.835); TIM12 (0.829)
Homologues (species, bitscore): YME1L1 (Homo sapiens, 476.9); Yme1l1 (Mus musculus, 476.5); LOC793098 (Danio rerio, 468.4); yme1l1 (Xenopus tropicalis, 468.0); CG3499 (Drosophila melanogaster, 450.7); ymel-1 (Caenorhabditis elegans, 454.1); ftsh4 (Arabidopsis thaliana, 551.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:582118-584361:+ | gene-YPR024W_AKU4011 | rna-NM_001184121.1_AKU4011 | cds-NP_015349.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:312787-315030:- | gene-YPR024W_BG1 | rna-NM_001184121.1_BG1 | cds-NP_015349.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:659778-662021:+ | gene-YPR024W_Bruggeman | rna-NM_001184121.1_Bruggeman | cds-NP_015349.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:703256-705499:+ | gene-YPR024W_CAT1 | rna-NM_001184121.1_CAT1 | cds-NP_015349.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:585804-588047:+ | gene-YPR024W_CBS1585 | rna-NM_001184121.1_CBS1585 | cds-NP_015349.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:600190-602433:+ | gene-YPR024W_CBS436 | rna-NM_001184121.1_CBS436 | cds-NP_015349.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:589553-591796:+ | gene-YPR024W_CBS6412 | rna-NM_001184121.1_CBS6412 | cds-NP_015349.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:582268-584511:+ | gene-YPR024W_CBS6413 | rna-NM_001184121.1_CBS6413 | cds-NP_015349.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:610453-612696:+ | gene-YPR024W_CENPK1137D | rna-NM_001184121.1_CENPK1137D | cds-NP_015349.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:580050-582293:+ | gene-YPR024W_EthanolRed | rna-NM_001184121.1_EthanolRed | cds-NP_015349.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:587852-590095:+ | gene-YPR024W_FaliES1 | rna-NM_001184121.1_FaliES1 | cds-NP_015349.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000116.1:37323-39566:- | gene-YPR024W_JAY291 | rna-NM_001184121.1_JAY291 | cds-NP_015349.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:600998-603241:+ | gene-YPR024W_MUCL30387 | rna-NM_001184121.1_MUCL30387 | cds-NP_015349.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:599662-601905:+ | gene-YPR024W_MUCL30388 | rna-NM_001184121.1_MUCL30388 | cds-NP_015349.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:579060-581303:+ | gene-YPR024W_MUCL39482 | rna-NM_001184121.1_MUCL39482 | cds-NP_015349.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:640375-642618:+ | gene-YPR024W_MUCL42920 | rna-NM_001184121.1_MUCL42920 | cds-NP_015349.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:610464-612707:+ | gene-YPR024W_NCIM3186 | rna-NM_001184121.1_NCIM3186 | cds-NP_015349.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:586991-589234:+ | gene-YPR024W_NCYC1407 | rna-NM_001184121.1_NCYC1407 | cds-NP_015349.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:593708-595951:+ | gene-YPR024W_PE2H3 | rna-NM_001184121.1_PE2H3 | cds-NP_015349.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:593356-595599:+ | gene-YPR024W_PE2H4 | rna-NM_001184121.1_PE2H4 | cds-NP_015349.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:610481-612724:+ | gene-YPR024W_S288C | rna-NM_001184121.1_S288C | cds-NP_015349.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:87591-89834:- | gene-YPR024W_SA1 | rna-NM_001184121.1_SA1 | cds-NP_015349.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:587654-589897:+ | gene-YPR024W_ThermosaccDry | rna-NM_001184121.1_ThermosaccDry | cds-NP_015349.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:603903-606146:+ | gene-YPR024W_VR1 | rna-NM_001184121.1_VR1 | cds-NP_015349.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:586959-589202:+ | gene-YPR024W_ZTW1 | rna-NM_001184121.1_ZTW1 | cds-NP_015349.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:587202-589445:+ | gene-YPR024W_Sparadoxus | rna-NM_001184121.1_Sparadoxus | cds-NP_015349.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |