Gene name: YLR446W
Reference locus (S288C): YLR446W
Gene biotype: protein_coding
Description: Putative hexokinase; transcript is upregulated during sporulation and the unfolded protein response; YLR446W is not an essential gene
Top 10 interactors (score): PGI1 (0.988); ZWF1 (0.981); HXK2 (0.976); FBP1 (0.974); PMI40 (0.971); HXK1 (0.968); SUC2 (0.965); GNA1 (0.939); NTH2 (0.934); NTH1 (0.933); GLK1 (0.933); PFK1 (0.93); GAL10 (0.912); SGA1 (0.91); SEC53 (0.906); DSF1 (0.901); YMR099C (0.901); FBA1 (0.891); PFK2 (0.88); ALG8 (0.859)
Homologues (species, bitscore): HKDC1 (Homo sapiens, 61.2); Hkdc1 (Mus musculus, 59.7); hk2 (Danio rerio, 64.3); Hkdc1 (Xenopus tropicalis, 56.2); Hex-A (Drosophila melanogaster, 57.0); F14B4.2 (Caenorhabditis elegans, 55.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:963479-964781:+ | gene-YLR446W_AKU4011 | rna-NM_001182334.1_AKU4011 | cds-NP_013551.1_AKU4011 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:195941-197242:+ | gene-YLR446W_BG1 | rna-NM_001182334.1_BG1 | cds-NP_013551.1_BG1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:1001796-1003097:+ | gene-YLR446W_Bruggeman | rna-NM_001182334.1_Bruggeman | cds-NP_013551.1_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:997795-999096:+ | gene-YLR446W_CAT1 | rna-NM_001182334.1_CAT1 | cds-NP_013551.1_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:999070-1000372:+ | gene-YLR446W_CBS1585 | rna-NM_001182334.1_CBS1585 | cds-NP_013551.1_CBS1585 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:988417-989718:+ | gene-YLR446W_CBS436 | rna-NM_001182334.1_CBS436 | cds-NP_013551.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:1035117-1036419:+ | gene-YLR446W_CBS6412 | rna-NM_001182334.1_CBS6412 | cds-NP_013551.1_CBS6412 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:999858-1001160:+ | gene-YLR446W_CBS6413 | rna-NM_001182334.1_CBS6413 | cds-NP_013551.1_CBS6413 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:1009820-1011121:+ | gene-YLR446W_CENPK1137D | rna-NM_001182334.1_CENPK1137D | cds-NP_013551.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:956502-957803:+ | gene-YLR446W_EthanolRed | rna-NM_001182334.1_EthanolRed | cds-NP_013551.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:991773-993074:+ | gene-YLR446W_FaliES1 | rna-NM_001182334.1_FaliES1 | cds-NP_013551.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000194.1:25596-26897:- | gene-YLR446W_JAY291 | rna-NM_001182334.1_JAY291 | cds-NP_013551.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:1000652-1001953:+ | gene-YLR446W_MUCL30387 | rna-NM_001182334.1_MUCL30387 | cds-NP_013551.1_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:1010486-1011787:+ | gene-YLR446W_MUCL30388 | rna-NM_001182334.1_MUCL30388 | cds-NP_013551.1_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:1000307-1001609:+ | gene-YLR446W_MUCL39482 | rna-NM_001182334.1_MUCL39482 | cds-NP_013551.1_MUCL39482 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:1000777-1002078:+ | gene-YLR446W_MUCL42920 | rna-NM_001182334.1_MUCL42920 | cds-NP_013551.1_MUCL42920 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:1025188-1026489:+ | gene-YLR446W_NCIM3186 | rna-NM_001182334.1_NCIM3186 | cds-NP_013551.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:1009723-1011025:+ | gene-YLR446W_NCYC1407 | rna-NM_001182334.1_NCYC1407 | cds-NP_013551.1_NCYC1407 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:996198-997499:+ | gene-YLR446W_PE2H3 | rna-NM_001182334.1_PE2H3 | cds-NP_013551.1_PE2H3 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:995942-997243:+ | gene-YLR446W_PE2H4 | rna-NM_001182334.1_PE2H4 | cds-NP_013551.1_PE2H4 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:1025214-1026515:+ | gene-YLR446W_S288C | rna-NM_001182334.1_S288C | cds-NP_013551.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:33357-34658:- | gene-YLR446W_SA1 | rna-NM_001182334.1_SA1 | cds-NP_013551.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:994852-996153:+ | gene-YLR446W_ThermosaccDry | rna-NM_001182334.1_ThermosaccDry | cds-NP_013551.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:1001283-1002584:+ | gene-YLR446W_VR1 | rna-NM_001182334.1_VR1 | cds-NP_013551.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:325125-326426:+ | gene-YLR446W_ZTW1 | rna-NM_001182334.1_ZTW1 | cds-NP_013551.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:974125-975426:+ | gene-YLR446W_Sparadoxus | rna-NM_001182334.1_Sparadoxus | cds-NP_013551.1_Sparadoxus | 90.0 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |