Gene name: YLR345W
Reference locus (S288C): YLR345W
Gene biotype: protein_coding
Description: Bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase; Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W; Similar to 6-phosphofructo-2-kinase enzymes; mRNA expression is repressed by the Rfx1p-Tup1p-Ssn6p repressor complex; YLR345W is not an essential gene; In the C-terminal section; belongs to the phosphoglycerate mutase family
Top 10 interactors (score): FBP26 (0.996); PFK1 (0.959); PFK2 (0.959); MSC1 (0.952); FBP1 (0.943); DCS2 (0.94); PFK26 (0.94); TPK1 (0.928); GGA1 (0.919); GLC3 (0.91); PMI40 (0.904); YLR149C (0.902); STF2 (0.901); TSL1 (0.9); PFK27 (0.9); TPK2 (0.897); DCS1 (0.888); PGM2 (0.875); GAD1 (0.873); HFD1 (0.87)
Homologues (species, bitscore): PFKFB4 (Homo sapiens, 202.6); Pfkfb4 (Mus musculus, 201.8); pfkfb4 (Danio rerio, 207.2); pfkfb3 (Xenopus tropicalis, 204.1); Pfrx (Drosophila melanogaster, 186.0); Y110A7A.6 (Caenorhabditis elegans, 196.8); F2KP (Arabidopsis thaliana, 192.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:770094-771623:+ | gene-YLR345W_AKU4011 | rna-NM_001182234.1_AKU4011 | cds-NP_013449.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:2171-3700:+ | gene-YLR345W_BG1 | rna-NM_001182234.1_BG1 | cds-NP_013449.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:806855-808384:+ | gene-YLR345W_Bruggeman | rna-NM_001182234.1_Bruggeman | cds-NP_013449.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:803900-805429:+ | gene-YLR345W_CAT1 | rna-NM_001182234.1_CAT1 | cds-NP_013449.1_CAT1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:805086-806615:+ | gene-YLR345W_CBS1585 | rna-NM_001182234.1_CBS1585 | cds-NP_013449.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:789312-790841:+ | gene-YLR345W_CBS436 | rna-NM_001182234.1_CBS436 | cds-NP_013449.1_CBS436 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:842084-843613:+ | gene-YLR345W_CBS6412 | rna-NM_001182234.1_CBS6412 | cds-NP_013449.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:806013-807542:+ | gene-YLR345W_CBS6413 | rna-NM_001182234.1_CBS6413 | cds-NP_013449.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:805126-806655:+ | gene-YLR345W_CENPK1137D | rna-NM_001182234.1_CENPK1137D | cds-NP_013449.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:762646-764175:+ | gene-YLR345W_EthanolRed | rna-NM_001182234.1_EthanolRed | cds-NP_013449.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:791453-792982:+ | gene-YLR345W_FaliES1 | rna-NM_001182234.1_FaliES1 | cds-NP_013449.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000161.1:2050-3579:+ | gene-YLR345W_JAY291 | rna-NM_001182234.1_JAY291 | cds-NP_013449.1_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:804836-806365:+ | gene-YLR345W_MUCL30387 | rna-NM_001182234.1_MUCL30387 | cds-NP_013449.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:810182-811711:+ | gene-YLR345W_MUCL30388 | rna-NM_001182234.1_MUCL30388 | cds-NP_013449.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:806305-807834:+ | gene-YLR345W_MUCL39482 | rna-NM_001182234.1_MUCL39482 | cds-NP_013449.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:801582-803111:+ | gene-YLR345W_MUCL42920 | rna-NM_001182234.1_MUCL42920 | cds-NP_013449.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:820485-822014:+ | gene-YLR345W_NCIM3186 | rna-NM_001182234.1_NCIM3186 | cds-NP_013449.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:815525-817054:+ | gene-YLR345W_NCYC1407 | rna-NM_001182234.1_NCYC1407 | cds-NP_013449.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:802469-803998:+ | gene-YLR345W_PE2H3 | rna-NM_001182234.1_PE2H3 | cds-NP_013449.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:802213-803742:+ | gene-YLR345W_PE2H4 | rna-NM_001182234.1_PE2H4 | cds-NP_013449.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:820511-822040:+ | gene-YLR345W_S288C | rna-NM_001182234.1_S288C | cds-NP_013449.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:226620-228149:- | gene-YLR345W_SA1 | rna-NM_001182234.1_SA1 | cds-NP_013449.1_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:794289-795818:+ | gene-YLR345W_ThermosaccDry | rna-NM_001182234.1_ThermosaccDry | cds-NP_013449.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:807545-809074:+ | gene-YLR345W_VR1 | rna-NM_001182234.1_VR1 | cds-NP_013449.1_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:131733-133262:+ | gene-YLR345W_ZTW1 | rna-NM_001182234.1_ZTW1 | cds-NP_013449.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:780341-781870:+ | gene-YLR345W_Sparadoxus | rna-NM_001182234.1_Sparadoxus | cds-NP_013449.1_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |