Gene name: YKU80
Reference locus (S288C): YMR106C
Gene biotype: protein_coding
Description: ATP-dependent DNA helicase II subunit 2; Subunit of telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein via interaction with TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair; colocalizes with quiescent cell telomere hyperclusters; Belongs to the ku80 family
Top 10 interactors (score): DNL4 (0.999); EST2 (0.999); SGS1 (0.999); YKU70 (0.999); SIR4 (0.999); MRE11 (0.998); TEL1 (0.99); RAD52 (0.99); CDC13 (0.985); EXO1 (0.983); EST1 (0.981); POL4 (0.965); RAD51 (0.96); MEC1 (0.957); RAD9 (0.955); LIF1 (0.955); SIR3 (0.944); TPP1 (0.942); PSO2 (0.941); NEJ1 (0.926)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:516250-518139:- | gene-YMR106C_AKU4011 | rna-NM_001182606.1_AKU4011 | cds-NP_013824.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:24816-26705:+ | gene-YMR106C_BG1 | rna-NM_001182606.1_BG1 | cds-NP_013824.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:458675-460564:- | gene-YMR106C_Bruggeman | rna-NM_001182606.1_Bruggeman | cds-NP_013824.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:458994-460883:- | gene-YMR106C_CAT1 | rna-NM_001182606.1_CAT1 | cds-NP_013824.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:449195-451084:- | gene-YMR106C_CBS1585 | rna-NM_001182606.1_CBS1585 | cds-NP_013824.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:454507-456396:- | gene-YMR106C_CBS436 | rna-NM_001182606.1_CBS436 | cds-NP_013824.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:562294-564183:- | gene-YMR106C_CBS6412 | rna-NM_001182606.1_CBS6412 | cds-NP_013824.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:448455-450344:- | gene-YMR106C_CBS6413 | rna-NM_001182606.1_CBS6413 | cds-NP_013824.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:472411-474300:- | gene-YMR106C_CENPK1137D | rna-NM_001182606.1_CENPK1137D | cds-NP_013824.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:449080-450969:- | gene-YMR106C_EthanolRed | rna-NM_001182606.1_EthanolRed | cds-NP_013824.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:452225-454114:- | gene-YMR106C_FaliES1 | rna-NM_001182606.1_FaliES1 | cds-NP_013824.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000349.1:15056-16945:- | gene-YMR106C_JAY291 | rna-NM_001182606.1_JAY291 | cds-NP_013824.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:455594-457483:- | gene-YMR106C_MUCL30387 | rna-NM_001182606.1_MUCL30387 | cds-NP_013824.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:459583-461472:- | gene-YMR106C_MUCL30388 | rna-NM_001182606.1_MUCL30388 | cds-NP_013824.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:449493-451382:- | gene-YMR106C_MUCL39482 | rna-NM_001182606.1_MUCL39482 | cds-NP_013824.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:456162-458051:- | gene-YMR106C_MUCL42920 | rna-NM_001182606.1_MUCL42920 | cds-NP_013824.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:478255-480144:- | gene-YMR106C_NCIM3186 | rna-NM_001182606.1_NCIM3186 | cds-NP_013824.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:449390-451279:- | gene-YMR106C_NCYC1407 | rna-NM_001182606.1_NCYC1407 | cds-NP_013824.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:455105-456994:- | gene-YMR106C_PE2H3 | rna-NM_001182606.1_PE2H3 | cds-NP_013824.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:461200-463089:- | gene-YMR106C_PE2H4 | rna-NM_001182606.1_PE2H4 | cds-NP_013824.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:478301-480190:- | gene-YMR106C_S288C | rna-NM_001182606.1_S288C | cds-NP_013824.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:69807-71696:+ | gene-YMR106C_SA1 | rna-NM_001182606.1_SA1 | cds-NP_013824.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:450047-451936:- | gene-YMR106C_ThermosaccDry | rna-NM_001182606.1_ThermosaccDry | cds-NP_013824.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:461691-463580:- | gene-YMR106C_VR1 | rna-NM_001182606.1_VR1 | cds-NP_013824.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:426329-428218:- | gene-YMR106C_ZTW1 | rna-NM_001182606.1_ZTW1 | cds-NP_013824.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:462547-464434:- | gene-YMR106C_Sparadoxus | rna-NM_001182606.1_Sparadoxus | cds-NP_013824.1_Sparadoxus | 91.3 | 99.8 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |