Gene name: YKU70
Reference locus (S288C): YMR284W
Gene biotype: protein_coding
Description: ATP-dependent DNA helicase II subunit 1; Subunit of the telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein to nucleus via interaction with the TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
Top 10 interactors (score): EST2 (0.999); YKU80 (0.999); SGS1 (0.999); DNL4 (0.999); RAD52 (0.998); EXO1 (0.998); RFA1 (0.998); MRE11 (0.997); TEL1 (0.994); SIR4 (0.993); RAD51 (0.992); POL4 (0.991); CHK1 (0.987); RAD50 (0.987); SIR2 (0.986); DNA2 (0.986); MEC1 (0.986); PIF1 (0.982); CDC13 (0.978); EST1 (0.978)
Homologues (species, bitscore): XRCC6 (Homo sapiens, 60.1); Xrcc6 (Mus musculus, 76.3); xrcc6 (Danio rerio, 66.6); xrcc6 (Xenopus tropicalis, 60.1); KU70 (Arabidopsis thaliana, 73.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:877238-879046:+ | gene-YMR284W_AKU4011 | rna-NM_001182791.1_AKU4011 | cds-NP_014011.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:74626-76434:- | gene-YMR284W_BG1 | rna-NM_001182791.1_BG1 | cds-NP_014011.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:822448-824256:+ | gene-YMR284W_Bruggeman | rna-NM_001182791.1_Bruggeman | cds-NP_014011.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:825733-827541:+ | gene-YMR284W_CAT1 | rna-NM_001182791.1_CAT1 | cds-NP_014011.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:809488-811296:+ | gene-YMR284W_CBS1585 | rna-NM_001182791.1_CBS1585 | cds-NP_014011.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:831804-833612:+ | gene-YMR284W_CBS436 | rna-NM_001182791.1_CBS436 | cds-NP_014011.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:921062-922870:+ | gene-YMR284W_CBS6412 | rna-NM_001182791.1_CBS6412 | cds-NP_014011.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:808609-810417:+ | gene-YMR284W_CBS6413 | rna-NM_001182791.1_CBS6413 | cds-NP_014011.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:832733-834541:+ | gene-YMR284W_CENPK1137D | rna-NM_001182791.1_CENPK1137D | cds-NP_014011.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:869928-871736:+ | gene-YMR284W_EthanolRed | rna-NM_001182791.1_EthanolRed | cds-NP_014011.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:815955-817763:+ | gene-YMR284W_FaliES1 | rna-NM_001182791.1_FaliES1 | cds-NP_014011.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000262.1:33969-35777:- | gene-YMR284W_JAY291 | rna-NM_001182791.1_JAY291 | cds-NP_014011.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:816273-818081:+ | gene-YMR284W_MUCL30387 | rna-NM_001182791.1_MUCL30387 | cds-NP_014011.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:825670-827478:+ | gene-YMR284W_MUCL30388 | rna-NM_001182791.1_MUCL30388 | cds-NP_014011.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:810576-812384:+ | gene-YMR284W_MUCL39482 | rna-NM_001182791.1_MUCL39482 | cds-NP_014011.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:819381-821189:+ | gene-YMR284W_MUCL42920 | rna-NM_001182791.1_MUCL42920 | cds-NP_014011.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:838141-839949:+ | gene-YMR284W_NCIM3186 | rna-NM_001182791.1_NCIM3186 | cds-NP_014011.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:810219-812027:+ | gene-YMR284W_NCYC1407 | rna-NM_001182791.1_NCYC1407 | cds-NP_014011.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:826025-827833:+ | gene-YMR284W_PE2H3 | rna-NM_001182791.1_PE2H3 | cds-NP_014011.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:821999-823807:+ | gene-YMR284W_PE2H4 | rna-NM_001182791.1_PE2H4 | cds-NP_014011.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:838187-839995:+ | gene-YMR284W_S288C | rna-NM_001182791.1_S288C | cds-NP_014011.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000036.1:15955-17763:+ | gene-YMR284W_SA1 | rna-NM_001182791.1_SA1 | cds-NP_014011.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:812124-813932:+ | gene-YMR284W_ThermosaccDry | rna-NM_001182791.1_ThermosaccDry | cds-NP_014011.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:825621-827678:+ | gene-YMR284W_VR1 | rna-NM_001182791.1_VR1 | cds-NP_014011.1_VR1 | 87.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:227358-229166:+ | gene-YMR284W_ZTW1 | rna-NM_001182791.1_ZTW1 | cds-NP_014011.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:830736-832544:+ | gene-YMR284W_Sparadoxus | rna-NM_001182791.1_Sparadoxus | cds-NP_014011.1_Sparadoxus | 87.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |