YKE4 (YIL023C)


Gene profile

Gene name: YKE4
Reference locus (S288C): YIL023C
Gene biotype: protein_coding

Description: Solute carrier family 39 (zinc transporter), member 7; Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family

Top 10 interactors (score): MSC2 (0.988); ZRT2 (0.986); ZRT3 (0.986); ZRT1 (0.983); ZRC1 (0.977); ATX2 (0.959); COT1 (0.957); ZRG17 (0.916); ZAP1 (0.913); MMT1 (0.848); YPF1 (0.827); SPO22 (0.761); FET4 (0.724); ZPS1 (0.717); CSR1 (0.713); MMT2 (0.705); CCC1 (0.684); SMF1 (0.664); ERV41 (0.661); CCC2 (0.65)

Homologues (species, bitscore): SLC39A7 (Homo sapiens, 148.7); Slc39a7 (Mus musculus, 151.8); slc39a7 (Danio rerio, 146.7); slc39a7 (Xenopus tropicalis, 146.4); Catsup (Drosophila melanogaster, 136.7); hke-4.2 (Caenorhabditis elegans, 181.4); IAR1 (Arabidopsis thaliana, 80.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:307843-308883:- gene-YIL023C_AKU4011 rna-NM_001179373.1_AKU4011 cds-NP_012241.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:167666-168706:- gene-YIL023C_BG1 rna-NM_001179373.1_BG1 cds-NP_012241.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:312983-314023:- gene-YIL023C_Bruggeman rna-NM_001179373.1_Bruggeman cds-NP_012241.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:300400-301440:- gene-YIL023C_CAT1 rna-NM_001179373.1_CAT1 cds-NP_012241.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:307932-308972:- gene-YIL023C_CBS1585 rna-NM_001179373.1_CBS1585 cds-NP_012241.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:301364-302404:- gene-YIL023C_CBS436 rna-NM_001179373.1_CBS436 cds-NP_012241.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:303464-304504:- gene-YIL023C_CBS6412 rna-NM_001179373.1_CBS6412 cds-NP_012241.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:299848-300888:- gene-YIL023C_CBS6413 rna-NM_001179373.1_CBS6413 cds-NP_012241.1_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:301295-302335:- gene-YIL023C_CENPK1137D rna-NM_001179373.1_CENPK1137D cds-NP_012241.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:290810-291850:- gene-YIL023C_EthanolRed rna-NM_001179373.1_EthanolRed cds-NP_012241.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:308721-309761:- gene-YIL023C_FaliES1 rna-NM_001179373.1_FaliES1 cds-NP_012241.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000098.1:7229-8269:+ gene-YIL023C_JAY291 rna-NM_001179373.1_JAY291 cds-NP_012241.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:309833-310873:- gene-YIL023C_MUCL30387 rna-NM_001179373.1_MUCL30387 cds-NP_012241.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:305938-306978:- gene-YIL023C_MUCL30388 rna-NM_001179373.1_MUCL30388 cds-NP_012241.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:308523-309563:- gene-YIL023C_MUCL39482 rna-NM_001179373.1_MUCL39482 cds-NP_012241.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:311651-312691:- gene-YIL023C_MUCL42920 rna-NM_001179373.1_MUCL42920 cds-NP_012241.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:309386-310426:- gene-YIL023C_NCIM3186 rna-NM_001179373.1_NCIM3186 cds-NP_012241.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:312796-313836:- gene-YIL023C_NCYC1407 rna-NM_001179373.1_NCYC1407 cds-NP_012241.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:304435-305475:- gene-YIL023C_PE2H3 rna-NM_001179373.1_PE2H3 cds-NP_012241.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:299141-300181:- gene-YIL023C_PE2H4 rna-NM_001179373.1_PE2H4 cds-NP_012241.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:309386-310426:- gene-YIL023C_S288C rna-NM_001179373.1_S288C cds-NP_012241.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000031.1:14108-15148:+ gene-YIL023C_SA1 rna-NM_001179373.1_SA1 cds-NP_012241.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:307390-308430:- gene-YIL023C_ThermosaccDry rna-NM_001179373.1_ThermosaccDry cds-NP_012241.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:304023-305063:- gene-YIL023C_VR1 rna-NM_001179373.1_VR1 cds-NP_012241.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:281810-282850:- gene-YIL023C_ZTW1 rna-NM_001179373.1_ZTW1 cds-NP_012241.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:302530-303573:- gene-YIL023C_Sparadoxus rna-NM_001179373.1_Sparadoxus cds-NP_012241.1_Sparadoxus 86.6 99.9 Verified 1 1 1 False True False False False

Additional files