Gene name: YJL070C
Reference locus (S288C): YJL070C
Gene biotype: protein_coding
Description: Inactive deaminase YJL070C; Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; may regulate purine nucleotide homeostasis as overexpression in an AMD1 strain grown in adenine results in greatly reduced GDP and GTP intracellular levels; not an essential gene; YJL070C has a paralog, YBR284W, that arose from the whole genome duplication
Top 10 interactors (score): AMD1 (0.898); IDS2 (0.85); YBR284W (0.819); PET127 (0.78); DLS1 (0.773); MPM1 (0.763); YJL068C (0.756); HBN1 (0.746); ARG2 (0.715); UTP18 (0.698); SCW11 (0.692); DPB3 (0.691); ADE12 (0.662); ADE13 (0.628); WHI2 (0.616); VPS5 (0.612); GUA1 (0.611); AAH1 (0.611); ADO1 (0.547); PNP1 (0.528)
Homologues (species, bitscore): AMPD2 (Homo sapiens, 231.1); Ampd2 (Mus musculus, 231.5); ampd2 (Danio rerio, 239.2); ampd3 (Xenopus tropicalis, 191.0); AMPdeam (Drosophila melanogaster, 218.4); C34F11.3 (Caenorhabditis elegans, 222.6); FAC1 (Arabidopsis thaliana, 216.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:290838-293501:- | gene-YJL070C_AKU4011 | rna-NM_001181503.3_AKU4011 | cds-NP_012465.3_AKU4011 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:321007-323673:+ | gene-YJL070C_BG1 | rna-NM_001181503.3_BG1 | cds-NP_012465.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:303377-306040:- | gene-YJL070C_Bruggeman | rna-NM_001181503.3_Bruggeman | cds-NP_012465.3_Bruggeman | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:307477-310140:- | gene-YJL070C_CAT1 | rna-NM_001181503.3_CAT1 | cds-NP_012465.3_CAT1 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:302499-305162:- | gene-YJL070C_CBS1585 | rna-NM_001181503.3_CBS1585 | cds-NP_012465.3_CBS1585 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:320503-323169:- | gene-YJL070C_CBS436 | rna-NM_001181503.3_CBS436 | cds-NP_012465.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:291596-294259:- | gene-YJL070C_CBS6412 | rna-NM_001181503.3_CBS6412 | cds-NP_012465.3_CBS6412 | 99.6 | 99.8 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:292952-295615:- | gene-YJL070C_CBS6413 | rna-NM_001181503.3_CBS6413 | cds-NP_012465.3_CBS6413 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:290441-293107:- | gene-YJL070C_CENPK1137D | rna-NM_001181503.3_CENPK1137D | cds-NP_012465.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:294676-297339:- | gene-YJL070C_EthanolRed | rna-NM_001181503.3_EthanolRed | cds-NP_012465.3_EthanolRed | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:306251-308914:- | gene-YJL070C_FaliES1 | rna-NM_001181503.3_FaliES1 | cds-NP_012465.3_FaliES1 | 99.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000138.1:103835-106501:- | gene-YJL070C_JAY291 | rna-NM_001181503.3_JAY291 | cds-NP_012465.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:304534-307197:- | gene-YJL070C_MUCL30387 | rna-NM_001181503.3_MUCL30387 | cds-NP_012465.3_MUCL30387 | 99.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:300570-303233:- | gene-YJL070C_MUCL30388 | rna-NM_001181503.3_MUCL30388 | cds-NP_012465.3_MUCL30388 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:295248-297911:- | gene-YJL070C_MUCL39482 | rna-NM_001181503.3_MUCL39482 | cds-NP_012465.3_MUCL39482 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:301898-304561:- | gene-YJL070C_MUCL42920 | rna-NM_001181503.3_MUCL42920 | cds-NP_012465.3_MUCL42920 | 99.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:307950-310616:- | gene-YJL070C_NCIM3186 | rna-NM_001181503.3_NCIM3186 | cds-NP_012465.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:293944-296607:- | gene-YJL070C_NCYC1407 | rna-NM_001181503.3_NCYC1407 | cds-NP_012465.3_NCYC1407 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:306298-308961:- | gene-YJL070C_PE2H3 | rna-NM_001181503.3_PE2H3 | cds-NP_012465.3_PE2H3 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:305942-308605:- | gene-YJL070C_PE2H4 | rna-NM_001181503.3_PE2H4 | cds-NP_012465.3_PE2H4 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:307971-310637:- | gene-YJL070C_S288C | rna-NM_001181503.3_S288C | cds-NP_012465.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:103860-106523:- | gene-YJL070C_SA1 | rna-NM_001181503.3_SA1 | cds-NP_012465.3_SA1 | 99.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:299664-302327:- | gene-YJL070C_ThermosaccDry | rna-NM_001181503.3_ThermosaccDry | cds-NP_012465.3_ThermosaccDry | 99.4 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:301841-304507:- | gene-YJL070C_VR1 | rna-NM_001181503.3_VR1 | cds-NP_012465.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:281050-283713:- | gene-YJL070C_ZTW1 | rna-NM_001181503.3_ZTW1 | cds-NP_012465.3_ZTW1 | 99.6 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:305085-307745:- | gene-YJL070C_Sparadoxus | rna-NM_001181503.3_Sparadoxus | cds-NP_012465.3_Sparadoxus | 90.1 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |