Gene name: YIH1
Reference locus (S288C): YCR059C
Gene biotype: protein_coding
Description: Protein IMPACT homolog; Negative regulator of eIF2 kinase Gcn2p; competes with Gcn2p for binding to Gcn1p; may contribute to regulation of translation in response to starvation via regulation of Gcn2p; binds to monomeric actin and to ribosomes and polyribosomes; ortholog of mammalian IMPACT; Belongs to the IMPACT family
Top 10 interactors (score): GIR2 (0.922); GCN2 (0.915); GCN1 (0.903); YLR419W (0.892); YJR096W (0.75); MRH4 (0.71); KRS1 (0.703); ATG14 (0.69); MSS116 (0.69); PDI1 (0.657); HAS1 (0.65); VMA1 (0.598); MSD1 (0.591); YEF3 (0.56); MSK1 (0.528); ACT1 (0.487); GAL10 (0.485); HTZ1 (0.482); TEF2 (0.473); CAR1 (0.408)
Homologues (species, bitscore): IMPACT (Homo sapiens, 120.2); Impact (Mus musculus, 126.7); impact (Danio rerio, 70.5); impact (Xenopus tropicalis, 114.8); impt-1 (Caenorhabditis elegans, 118.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:217913-218689:- | gene-YCR059C_AKU4011 | rna-NM_001178770.1_AKU4011 | cds-NP_009985.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000067.1:72115-72891:- | gene-YCR059C_BG1 | rna-NM_001178770.1_BG1 | cds-NP_009985.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:213872-214648:- | gene-YCR059C_Bruggeman | rna-NM_001178770.1_Bruggeman | cds-NP_009985.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:225245-226021:- | gene-YCR059C_CAT1 | rna-NM_001178770.1_CAT1 | cds-NP_009985.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:212691-213467:- | gene-YCR059C_CBS1585 | rna-NM_001178770.1_CBS1585 | cds-NP_009985.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:224587-225363:- | gene-YCR059C_CBS436 | rna-NM_001178770.1_CBS436 | cds-NP_009985.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:204431-205207:- | gene-YCR059C_CBS6412 | rna-NM_001178770.1_CBS6412 | cds-NP_009985.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:218808-219584:- | gene-YCR059C_CBS6413 | rna-NM_001178770.1_CBS6413 | cds-NP_009985.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:222637-223413:- | gene-YCR059C_CENPK1137D | rna-NM_001178770.1_CENPK1137D | cds-NP_009985.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:213876-214652:- | gene-YCR059C_EthanolRed | rna-NM_001178770.1_EthanolRed | cds-NP_009985.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:219041-219817:- | gene-YCR059C_FaliES1 | rna-NM_001178770.1_FaliES1 | cds-NP_009985.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000014.1:3365-4141:+ | gene-YCR059C_JAY291 | rna-NM_001178770.1_JAY291 | cds-NP_009985.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:210856-211632:- | gene-YCR059C_MUCL30387 | rna-NM_001178770.1_MUCL30387 | cds-NP_009985.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:210230-211006:- | gene-YCR059C_MUCL30388 | rna-NM_001178770.1_MUCL30388 | cds-NP_009985.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:219264-220040:- | gene-YCR059C_MUCL39482 | rna-NM_001178770.1_MUCL39482 | cds-NP_009985.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:215706-216482:- | gene-YCR059C_MUCL42920 | rna-NM_001178770.1_MUCL42920 | cds-NP_009985.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:223086-223862:- | gene-YCR059C_NCIM3186 | rna-NM_001178770.1_NCIM3186 | cds-NP_009985.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:220123-220899:- | gene-YCR059C_NCYC1407 | rna-NM_001178770.1_NCYC1407 | cds-NP_009985.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:228800-229576:- | gene-YCR059C_PE2H3 | rna-NM_001178770.1_PE2H3 | cds-NP_009985.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:223325-224101:- | gene-YCR059C_PE2H4 | rna-NM_001178770.1_PE2H4 | cds-NP_009985.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:223454-224230:- | gene-YCR059C_S288C | rna-NM_001178770.1_S288C | cds-NP_009985.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000044.1:23340-24116:- | gene-YCR059C_SA1 | rna-NM_001178770.1_SA1 | cds-NP_009985.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:219024-219800:- | gene-YCR059C_ThermosaccDry | rna-NM_001178770.1_ThermosaccDry | cds-NP_009985.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:230298-231074:- | gene-YCR059C_VR1 | rna-NM_001178770.1_VR1 | cds-NP_009985.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:216845-217621:- | gene-YCR059C_ZTW1 | rna-NM_001178770.1_ZTW1 | cds-NP_009985.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:250989-251761:- | gene-YCR059C_Sparadoxus | rna-NM_001178770.1_Sparadoxus | cds-NP_009985.1_Sparadoxus | 90.9 | 99.4 | Verified | 1 | 1 | 0 | False | False | False | True | False |