YHC3 (YJL059W)


Gene profile

Gene name: YHC3
Reference locus (S288C): YJL059W
Gene biotype: protein_coding

Description: Amino acid transporter yhc3; Protein required for the ATP-dependent transport of arginine; vacuolar membrane protein; involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; human homolog CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis) can complement yeast null mutant

Top 10 interactors (score): BTN2 (0.913); PMA2 (0.908); HSP30 (0.904); RHB1 (0.872); ALP1 (0.867); CAN1 (0.849); IST2 (0.811); PMA1 (0.79); YBR287W (0.768); SDO1 (0.761); AVT6 (0.747); YIF1 (0.735); AVT4 (0.71); YRA2 (0.7); AVT3 (0.699); VBA3 (0.647); ERS1 (0.635); HAS1 (0.6); AVT1 (0.599); YPR114W (0.598)

Homologues (species, bitscore): CLN3 (Homo sapiens, 200.7); Cln3 (Mus musculus, 192.2); cln3 (Danio rerio, 180.6); cln3 (Xenopus tropicalis, 150.2); cln3 (Drosophila melanogaster, 182.2); cln-3.3 (Caenorhabditis elegans, 183.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:307827-309053:+ gene-YJL059W_AKU4011 rna-NM_001181492.1_AKU4011 cds-NP_012476.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:304792-306018:- gene-YJL059W_BG1 rna-NM_001181492.1_BG1 cds-NP_012476.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:320361-321587:+ gene-YJL059W_Bruggeman rna-NM_001181492.1_Bruggeman cds-NP_012476.1_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:324472-325698:+ gene-YJL059W_CAT1 rna-NM_001181492.1_CAT1 cds-NP_012476.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:319481-320707:+ gene-YJL059W_CBS1585 rna-NM_001181492.1_CBS1585 cds-NP_012476.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:337490-338716:+ gene-YJL059W_CBS436 rna-NM_001181492.1_CBS436 cds-NP_012476.1_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:308585-309811:+ gene-YJL059W_CBS6412 rna-NM_001181492.1_CBS6412 cds-NP_012476.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:309932-311158:+ gene-YJL059W_CBS6413 rna-NM_001181492.1_CBS6413 cds-NP_012476.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:307432-308658:+ gene-YJL059W_CENPK1137D rna-NM_001181492.1_CENPK1137D cds-NP_012476.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:311664-312890:+ gene-YJL059W_EthanolRed rna-NM_001181492.1_EthanolRed cds-NP_012476.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:323239-324465:+ gene-YJL059W_FaliES1 rna-NM_001181492.1_FaliES1 cds-NP_012476.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000138.1:120828-122054:+ gene-YJL059W_JAY291 rna-NM_001181492.1_JAY291 cds-NP_012476.1_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:321517-322743:+ gene-YJL059W_MUCL30387 rna-NM_001181492.1_MUCL30387 cds-NP_012476.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:317553-318779:+ gene-YJL059W_MUCL30388 rna-NM_001181492.1_MUCL30388 cds-NP_012476.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:312235-313461:+ gene-YJL059W_MUCL39482 rna-NM_001181492.1_MUCL39482 cds-NP_012476.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:318885-320111:+ gene-YJL059W_MUCL42920 rna-NM_001181492.1_MUCL42920 cds-NP_012476.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:324943-326169:+ gene-YJL059W_NCIM3186 rna-NM_001181492.1_NCIM3186 cds-NP_012476.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:310931-312157:+ gene-YJL059W_NCYC1407 rna-NM_001181492.1_NCYC1407 cds-NP_012476.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:323282-324508:+ gene-YJL059W_PE2H3 rna-NM_001181492.1_PE2H3 cds-NP_012476.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:322927-324153:+ gene-YJL059W_PE2H4 rna-NM_001181492.1_PE2H4 cds-NP_012476.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:324964-326190:+ gene-YJL059W_S288C rna-NM_001181492.1_S288C cds-NP_012476.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:120846-122072:+ gene-YJL059W_SA1 rna-NM_001181492.1_SA1 cds-NP_012476.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:316652-317878:+ gene-YJL059W_ThermosaccDry rna-NM_001181492.1_ThermosaccDry cds-NP_012476.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:318844-320070:+ gene-YJL059W_VR1 rna-NM_001181492.1_VR1 cds-NP_012476.1_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:298029-299255:+ gene-YJL059W_ZTW1 rna-NM_001181492.1_ZTW1 cds-NP_012476.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:322035-323258:+ gene-YJL059W_Sparadoxus rna-NM_001181492.1_Sparadoxus cds-NP_012476.1_Sparadoxus 89.9 99.7 Verified 1 1 1 False True False False False

Additional files