Gene name: YHB1
Reference locus (S288C): YGR234W
Gene biotype: protein_coding
Description: Flavohemoprotein; Nitric oxide oxidoreductase; flavohemoglobin that plays role in oxidative and nitrosative stress responses; protects against nitration of cellular targets and against cell growth inhibition under aerobic or anaerobic conditions; yeast flavohemoglobin Yhb1p and human homolog neuroglobin NGB protect cells against alpha-synuclein cytotoxicity and aggregate formation; protein increases in abundance, relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family
Top 10 interactors (score): PUF3 (0.761); FZF1 (0.759); SSU1 (0.752); SFA1 (0.75); HEM2 (0.749); PXR1 (0.745); YGR026W (0.714); OLE1 (0.682); RTC3 (0.675); HEM13 (0.67); RAD51 (0.662); TRX1 (0.65); HEM4 (0.647); SCS7 (0.619); TRX2 (0.617); YAP7 (0.616); HBN1 (0.61); ARO1 (0.592); AHP1 (0.584); MDH1 (0.581)
Homologues (species, bitscore): NGB (Homo sapiens, 60.5); Ngb (Mus musculus, 57.4); ngb (Danio rerio, 51.2); ngb (Xenopus tropicalis, 57.0); CG11257 (Drosophila melanogaster, 58.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:925310-926509:+ | gene-YGR234W_AKU4011 | rna-NM_001181363.1_AKU4011 | cds-NP_011750.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:205416-206615:+ | gene-YGR234W_BG1 | rna-NM_001181363.1_BG1 | cds-NP_011750.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:932904-934103:+ | gene-YGR234W_Bruggeman | rna-NM_001181363.1_Bruggeman | cds-NP_011750.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:932447-933646:+ | gene-YGR234W_CAT1 | rna-NM_001181363.1_CAT1 | cds-NP_011750.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:928174-929373:+ | gene-YGR234W_CBS1585 | rna-NM_001181363.1_CBS1585 | cds-NP_011750.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:931823-933022:+ | gene-YGR234W_CBS436 | rna-NM_001181363.1_CBS436 | cds-NP_011750.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:919052-920251:+ | gene-YGR234W_CBS6412 | rna-NM_001181363.1_CBS6412 | cds-NP_011750.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:925103-926302:+ | gene-YGR234W_CBS6413 | rna-NM_001181363.1_CBS6413 | cds-NP_011750.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:959551-960750:+ | gene-YGR234W_CENPK1137D | rna-NM_001181363.1_CENPK1137D | cds-NP_011750.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:913152-914351:+ | gene-YGR234W_EthanolRed | rna-NM_001181363.1_EthanolRed | cds-NP_011750.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:917958-919157:+ | gene-YGR234W_FaliES1 | rna-NM_001181363.1_FaliES1 | cds-NP_011750.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:111138-112337:- | gene-YGR234W_JAY291 | rna-NM_001181363.1_JAY291 | cds-NP_011750.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:930820-932019:+ | gene-YGR234W_MUCL30387 | rna-NM_001181363.1_MUCL30387 | cds-NP_011750.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:930084-931283:+ | gene-YGR234W_MUCL30388 | rna-NM_001181363.1_MUCL30388 | cds-NP_011750.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:923300-924499:+ | gene-YGR234W_MUCL39482 | rna-NM_001181363.1_MUCL39482 | cds-NP_011750.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:941801-943000:+ | gene-YGR234W_MUCL42920 | rna-NM_001181363.1_MUCL42920 | cds-NP_011750.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:959904-961103:+ | gene-YGR234W_NCIM3186 | rna-NM_001181363.1_NCIM3186 | cds-NP_011750.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:918914-920113:+ | gene-YGR234W_NCYC1407 | rna-NM_001181363.1_NCYC1407 | cds-NP_011750.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:944094-945293:+ | gene-YGR234W_PE2H3 | rna-NM_001181363.1_PE2H3 | cds-NP_011750.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:948933-950132:+ | gene-YGR234W_PE2H4 | rna-NM_001181363.1_PE2H4 | cds-NP_011750.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:959904-961103:+ | gene-YGR234W_S288C | rna-NM_001181363.1_S288C | cds-NP_011750.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000045.1:40393-41592:- | gene-YGR234W_SA1 | rna-NM_001181363.1_SA1 | cds-NP_011750.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:938485-939684:+ | gene-YGR234W_ThermosaccDry | rna-NM_001181363.1_ThermosaccDry | cds-NP_011750.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1043743-1044942:+ | gene-YGR234W_VR1 | rna-NM_001181363.1_VR1 | cds-NP_011750.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:239893-241092:+ | gene-YGR234W_ZTW1 | rna-NM_001181363.1_ZTW1 | cds-NP_011750.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:930678-931877:+ | gene-YGR234W_Sparadoxus | rna-NM_001181363.1_Sparadoxus | cds-NP_011750.1_Sparadoxus | 89.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |