YGK3 (YOL128C)


Gene profile

Gene name: YGK3
Reference locus (S288C): YOL128C
Gene biotype: protein_coding

Description: Glycogen synthase kinase-3 homolog YGK3; Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication

Top 10 interactors (score): CAK1 (0.961); SSN3 (0.907); PGM2 (0.812); DAS2 (0.739); FUR1 (0.739); URK1 (0.739); RGS2 (0.736); SST2 (0.736); SKI8 (0.72); TAF5 (0.72); HRR25 (0.716); CRZ1 (0.713); SPT16 (0.711); TRM13 (0.698); KIN28 (0.695); PKP2 (0.685); MSN2 (0.676); RPB3 (0.668); RPO26 (0.66); BMH2 (0.659)

Homologues (species, bitscore): GSK3B (Homo sapiens, 219.9); Gsk3b (Mus musculus, 221.9); gsk3b (Danio rerio, 220.7); gsk3b (Xenopus tropicalis, 220.7); gskt (Drosophila melanogaster, 217.6); gsk-3 (Caenorhabditis elegans, 222.6); ATSK12 (Arabidopsis thaliana, 216.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:67008-68135:- gene-YOL128C_AKU4011 rna-NM_001183382.1_AKU4011 cds-NP_014513.1_AKU4011 98.9 99.9 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000172.1:32631-33758:- gene-YOL128C_BG1 rna-NM_001183382.1_BG1 cds-NP_014513.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:68284-69411:- gene-YOL128C_Bruggeman rna-NM_001183382.1_Bruggeman cds-NP_014513.1_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:67242-68369:- gene-YOL128C_CAT1 rna-NM_001183382.1_CAT1 cds-NP_014513.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:61484-62611:- gene-YOL128C_CBS1585 rna-NM_001183382.1_CBS1585 cds-NP_014513.1_CBS1585 98.8 99.9 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:67332-68459:- gene-YOL128C_CBS436 rna-NM_001183382.1_CBS436 cds-NP_014513.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:61348-62475:- gene-YOL128C_CBS6412 rna-NM_001183382.1_CBS6412 cds-NP_014513.1_CBS6412 98.9 99.9 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:67816-68943:- gene-YOL128C_CBS6413 rna-NM_001183382.1_CBS6413 cds-NP_014513.1_CBS6413 98.9 99.9 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:78249-79376:- gene-YOL128C_CENPK1137D rna-NM_001183382.1_CENPK1137D cds-NP_014513.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:65259-66386:- gene-YOL128C_EthanolRed rna-NM_001183382.1_EthanolRed cds-NP_014513.1_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:67288-68415:- gene-YOL128C_FaliES1 rna-NM_001183382.1_FaliES1 cds-NP_014513.1_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000329.1:14132-15259:+ gene-YOL128C_JAY291 rna-NM_001183382.1_JAY291 cds-NP_014513.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:72924-74051:- gene-YOL128C_MUCL30387 rna-NM_001183382.1_MUCL30387 cds-NP_014513.1_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:75919-77046:- gene-YOL128C_MUCL30388 rna-NM_001183382.1_MUCL30388 cds-NP_014513.1_MUCL30388 99.0 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:69419-70546:- gene-YOL128C_MUCL39482 rna-NM_001183382.1_MUCL39482 cds-NP_014513.1_MUCL39482 98.8 99.9 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:85304-86431:- gene-YOL128C_MUCL42920 rna-NM_001183382.1_MUCL42920 cds-NP_014513.1_MUCL42920 98.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:78241-79368:- gene-YOL128C_NCIM3186 rna-NM_001183382.1_NCIM3186 cds-NP_014513.1_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:75458-76585:- gene-YOL128C_NCYC1407 rna-NM_001183382.1_NCYC1407 cds-NP_014513.1_NCYC1407 98.9 99.9 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:53891-55018:- gene-YOL128C_PE2H3 rna-NM_001183382.1_PE2H3 cds-NP_014513.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:70839-71966:- gene-YOL128C_PE2H4 rna-NM_001183382.1_PE2H4 cds-NP_014513.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:78352-79479:- gene-YOL128C_S288C rna-NM_001183382.1_S288C cds-NP_014513.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:51780-52907:- gene-YOL128C_SA1 rna-NM_001183382.1_SA1 cds-NP_014513.1_SA1 96.6 99.9 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:66426-67553:- gene-YOL128C_ThermosaccDry rna-NM_001183382.1_ThermosaccDry cds-NP_014513.1_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:67086-68213:- gene-YOL128C_VR1 rna-NM_001183382.1_VR1 cds-NP_014513.1_VR1 88.3 100.0 Verified 1 1 0 False False False True False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000031.1:66180-67307:- gene-YOL128C_ZTW1 rna-NM_001183382.1_ZTW1 cds-NP_014513.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:68870-69997:- gene-YOL128C_Sparadoxus rna-NM_001183382.1_Sparadoxus cds-NP_014513.1_Sparadoxus 89.2 99.8 Verified 1 1 1 False True False False False

Additional files