Gene name: YFH1
Reference locus (S288C): YDL120W
Gene biotype: protein_coding
Description: Frataxin homolog, mitochondrial; Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog FXN is mutated in Friedrich's ataxia; human FTL gene can complement yeast yfh1 null mutant
Top 10 interactors (score): ISU1 (0.999); YAH1 (0.999); NFS1 (0.999); ISD11 (0.999); JAC1 (0.998); HEM15 (0.998); ISU2 (0.992); GRX5 (0.987); ATM1 (0.98); MRS3 (0.98); SSQ1 (0.975); MRS4 (0.973); ISA1 (0.964); IBA57 (0.961); NFU1 (0.95); MGE1 (0.95); MAS1 (0.943); ISA2 (0.942); HSP60 (0.936); MAS2 (0.919)
Homologues (species, bitscore): FXN (Homo sapiens, 80.1); Fxn (Mus musculus, 80.9); fxn (Danio rerio, 77.4); fh (Drosophila melanogaster, 82.0); frh-1 (Caenorhabditis elegans, 82.0); FH (Arabidopsis thaliana, 80.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:230548-231072:+ | gene-YDL120W_AKU4011 | rna-NM_001180179.1_AKU4011 | cds-NP_010163.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:318880-319404:- | gene-YDL120W_BG1 | rna-NM_001180179.1_BG1 | cds-NP_010163.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:247956-248480:+ | gene-YDL120W_Bruggeman | rna-NM_001180179.1_Bruggeman | cds-NP_010163.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:244699-245223:+ | gene-YDL120W_CAT1 | rna-NM_001180179.1_CAT1 | cds-NP_010163.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:228809-229333:+ | gene-YDL120W_CBS1585 | rna-NM_001180179.1_CBS1585 | cds-NP_010163.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:245465-245989:+ | gene-YDL120W_CBS436 | rna-NM_001180179.1_CBS436 | cds-NP_010163.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:227234-227758:+ | gene-YDL120W_CBS6412 | rna-NM_001180179.1_CBS6412 | cds-NP_010163.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:246969-247493:+ | gene-YDL120W_CBS6413 | rna-NM_001180179.1_CBS6413 | cds-NP_010163.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:244695-245219:+ | gene-YDL120W_CENPK1137D | rna-NM_001180179.1_CENPK1137D | cds-NP_010163.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:241573-242097:+ | gene-YDL120W_EthanolRed | rna-NM_001180179.1_EthanolRed | cds-NP_010163.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:247543-248067:+ | gene-YDL120W_FaliES1 | rna-NM_001180179.1_FaliES1 | cds-NP_010163.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:17587-18111:+ | gene-YDL120W_JAY291 | rna-NM_001180179.1_JAY291 | cds-NP_010163.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:245743-246267:+ | gene-YDL120W_MUCL30387 | rna-NM_001180179.1_MUCL30387 | cds-NP_010163.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:236501-237025:+ | gene-YDL120W_MUCL30388 | rna-NM_001180179.1_MUCL30388 | cds-NP_010163.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:229913-230437:+ | gene-YDL120W_MUCL39482 | rna-NM_001180179.1_MUCL39482 | cds-NP_010163.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:151695-152219:+ | gene-YDL120W_MUCL42920 | rna-NM_001180179.1_MUCL42920 | cds-NP_010163.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:245846-246370:+ | gene-YDL120W_NCIM3186 | rna-NM_001180179.1_NCIM3186 | cds-NP_010163.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:229942-230466:+ | gene-YDL120W_NCYC1407 | rna-NM_001180179.1_NCYC1407 | cds-NP_010163.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:236698-237222:+ | gene-YDL120W_PE2H3 | rna-NM_001180179.1_PE2H3 | cds-NP_010163.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:236702-237226:+ | gene-YDL120W_PE2H4 | rna-NM_001180179.1_PE2H4 | cds-NP_010163.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:245923-246447:+ | gene-YDL120W_S288C | rna-NM_001180179.1_S288C | cds-NP_010163.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:188468-188992:- | gene-YDL120W_SA1 | rna-NM_001180179.1_SA1 | cds-NP_010163.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:247054-247578:+ | gene-YDL120W_ThermosaccDry | rna-NM_001180179.1_ThermosaccDry | cds-NP_010163.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:249160-249684:+ | gene-YDL120W_VR1 | rna-NM_001180179.1_VR1 | cds-NP_010163.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:244983-245507:+ | gene-YDL120W_ZTW1 | rna-NM_001180179.1_ZTW1 | cds-NP_010163.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:247085-247606:+ | gene-YDL120W_Sparadoxus | rna-NM_001180179.1_Sparadoxus | cds-NP_010163.1_Sparadoxus | 90.8 | 99.4 | Verified | 1 | 1 | 1 | False | True | False | False | False |