YEF1 (YEL041W)


Gene profile

Gene name: YEF1
Reference locus (S288C): YEL041W
Gene biotype: protein_coding

Description: ATP-NADH kinase; phosphorylates both NAD and NADH; homooctameric structure consisting of 60-kDa subunits; similar to Pos5p; overexpression complements certain pos5 phenotypes; YEF1 has a paralog, UTR1, that arose from the whole genome duplication

Top 10 interactors (score): UTR1 (0.999); ALD4 (0.954); ALD3 (0.95); ZWF1 (0.947); ALD6 (0.943); IDP2 (0.911); ALD5 (0.909); ALD2 (0.905); HFD1 (0.903); SOL4 (0.794); GND2 (0.723); NPT1 (0.713); NMA1 (0.704); ARG5,6 (0.703); POS5 (0.668); YMR226C (0.651); BNA6 (0.586); GOR1 (0.579); MAE1 (0.548); NMA2 (0.537)

Homologues (species, bitscore): NADK (Homo sapiens, 239.6); Nadk (Mus musculus, 238.0); nadkb (Danio rerio, 231.1); nadk (Xenopus tropicalis, 230.7); CG33156 (Drosophila melanogaster, 253.8); NADK1 (Arabidopsis thaliana, 251.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:70009-71496:+ gene-YEL041W_AKU4011 rna-NM_001178856.1_AKU4011 cds-NP_010873.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000075.1:9053-10540:- gene-YEL041W_BG1 rna-NM_001178856.1_BG1 cds-NP_010873.1_BG1 98.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:74150-75637:+ gene-YEL041W_Bruggeman rna-NM_001178856.1_Bruggeman cds-NP_010873.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:71939-73426:+ gene-YEL041W_CAT1 rna-NM_001178856.1_CAT1 cds-NP_010873.1_CAT1 98.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:69954-71441:+ gene-YEL041W_CBS1585 rna-NM_001178856.1_CBS1585 cds-NP_010873.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:71582-73069:+ gene-YEL041W_CBS436 rna-NM_001178856.1_CBS436 cds-NP_010873.1_CBS436 99.0 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:70206-71693:+ gene-YEL041W_CBS6412 rna-NM_001178856.1_CBS6412 cds-NP_010873.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:74846-76333:+ gene-YEL041W_CBS6413 rna-NM_001178856.1_CBS6413 cds-NP_010873.1_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:73797-75284:+ gene-YEL041W_CENPK1137D rna-NM_001178856.1_CENPK1137D cds-NP_010873.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:69760-71247:+ gene-YEL041W_EthanolRed rna-NM_001178856.1_EthanolRed cds-NP_010873.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:70023-71510:+ gene-YEL041W_FaliES1 rna-NM_001178856.1_FaliES1 cds-NP_010873.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000022.1:8304-9791:- gene-YEL041W_JAY291 rna-NM_001178856.1_JAY291 cds-NP_010873.1_JAY291 98.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:74207-75694:+ gene-YEL041W_MUCL30387 rna-NM_001178856.1_MUCL30387 cds-NP_010873.1_MUCL30387 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:70065-71552:+ gene-YEL041W_MUCL30388 rna-NM_001178856.1_MUCL30388 cds-NP_010873.1_MUCL30388 99.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:69323-70810:+ gene-YEL041W_MUCL39482 rna-NM_001178856.1_MUCL39482 cds-NP_010873.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:73957-75444:+ gene-YEL041W_MUCL42920 rna-NM_001178856.1_MUCL42920 cds-NP_010873.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:75943-77430:+ gene-YEL041W_NCIM3186 rna-NM_001178856.1_NCIM3186 cds-NP_010873.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:74417-75904:+ gene-YEL041W_NCYC1407 rna-NM_001178856.1_NCYC1407 cds-NP_010873.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:78442-79929:+ gene-YEL041W_PE2H3 rna-NM_001178856.1_PE2H3 cds-NP_010873.1_PE2H3 98.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:74357-75844:+ gene-YEL041W_PE2H4 rna-NM_001178856.1_PE2H4 cds-NP_010873.1_PE2H4 98.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:75944-77431:+ gene-YEL041W_S288C rna-NM_001178856.1_S288C cds-NP_010873.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000053.1:9140-10627:- gene-YEL041W_SA1 rna-NM_001178856.1_SA1 cds-NP_010873.1_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:70422-71909:+ gene-YEL041W_ThermosaccDry rna-NM_001178856.1_ThermosaccDry cds-NP_010873.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:69645-71132:+ gene-YEL041W_VR1 rna-NM_001178856.1_VR1 cds-NP_010873.1_VR1 98.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:69355-70842:+ gene-YEL041W_ZTW1 rna-NM_001178856.1_ZTW1 cds-NP_010873.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:71994-73466:+ gene-YEL041W_Sparadoxus rna-NM_001178856.1_Sparadoxus cds-NP_010873.1_Sparadoxus 88.0 98.8 Verified 1 1 1 False True False False False

Additional files