Gene name: YDL124W
Reference locus (S288C): YDL124W
Gene biotype: protein_coding
Description: NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): MSC1 (0.98); TPS1 (0.962); YNL134C (0.93); RTC3 (0.915); GRX2 (0.914); ETR1 (0.912); YET3 (0.91); GRX1 (0.91); TFS1 (0.903); SOL4 (0.903); HSP104 (0.899); YLR126C (0.896); PNC1 (0.89); PGC1 (0.89); GLK1 (0.887); YLL056C (0.883); GAD1 (0.883); PGM2 (0.872); STF2 (0.862); NTH1 (0.82)
Homologues (species, bitscore): AKR1A1 (Homo sapiens, 129.0); Akr1c6 (Mus musculus, 127.5); zgc:110366 (Danio rerio, 151.8); akr1a1 (Xenopus tropicalis, 132.9); CG10638 (Drosophila melanogaster, 140.6); ZC443.1 (Caenorhabditis elegans, 141.0); AT2G21250 (Arabidopsis thaliana, 143.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:224877-225815:+ | gene-YDL124W_AKU4011 | rna-NM_001180183.1_AKU4011 | cds-NP_010159.1_AKU4011 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:324130-325068:- | gene-YDL124W_BG1 | rna-NM_001180183.1_BG1 | cds-NP_010159.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:242024-242962:+ | gene-YDL124W_Bruggeman | rna-NM_001180183.1_Bruggeman | cds-NP_010159.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:239026-239964:+ | gene-YDL124W_CAT1 | rna-NM_001180183.1_CAT1 | cds-NP_010159.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:223138-224076:+ | gene-YDL124W_CBS1585 | rna-NM_001180183.1_CBS1585 | cds-NP_010159.1_CBS1585 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:239801-240739:+ | gene-YDL124W_CBS436 | rna-NM_001180183.1_CBS436 | cds-NP_010159.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:221563-222501:+ | gene-YDL124W_CBS6412 | rna-NM_001180183.1_CBS6412 | cds-NP_010159.1_CBS6412 | 98.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:241298-242236:+ | gene-YDL124W_CBS6413 | rna-NM_001180183.1_CBS6413 | cds-NP_010159.1_CBS6413 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:239031-239969:+ | gene-YDL124W_CENPK1137D | rna-NM_001180183.1_CENPK1137D | cds-NP_010159.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:235903-236841:+ | gene-YDL124W_EthanolRed | rna-NM_001180183.1_EthanolRed | cds-NP_010159.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:241873-242811:+ | gene-YDL124W_FaliES1 | rna-NM_001180183.1_FaliES1 | cds-NP_010159.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000010.1:11923-12861:+ | gene-YDL124W_JAY291 | rna-NM_001180183.1_JAY291 | cds-NP_010159.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:240079-241017:+ | gene-YDL124W_MUCL30387 | rna-NM_001180183.1_MUCL30387 | cds-NP_010159.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:230837-231775:+ | gene-YDL124W_MUCL30388 | rna-NM_001180183.1_MUCL30388 | cds-NP_010159.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:224242-225180:+ | gene-YDL124W_MUCL39482 | rna-NM_001180183.1_MUCL39482 | cds-NP_010159.1_MUCL39482 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:146032-146970:+ | gene-YDL124W_MUCL42920 | rna-NM_001180183.1_MUCL42920 | cds-NP_010159.1_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:240182-241120:+ | gene-YDL124W_NCIM3186 | rna-NM_001180183.1_NCIM3186 | cds-NP_010159.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:224271-225209:+ | gene-YDL124W_NCYC1407 | rna-NM_001180183.1_NCYC1407 | cds-NP_010159.1_NCYC1407 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:231027-231965:+ | gene-YDL124W_PE2H3 | rna-NM_001180183.1_PE2H3 | cds-NP_010159.1_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:231031-231969:+ | gene-YDL124W_PE2H4 | rna-NM_001180183.1_PE2H4 | cds-NP_010159.1_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:240259-241197:+ | gene-YDL124W_S288C | rna-NM_001180183.1_S288C | cds-NP_010159.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000010.1:193702-194640:- | gene-YDL124W_SA1 | rna-NM_001180183.1_SA1 | cds-NP_010159.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:241384-242322:+ | gene-YDL124W_ThermosaccDry | rna-NM_001180183.1_ThermosaccDry | cds-NP_010159.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:243489-244427:+ | gene-YDL124W_VR1 | rna-NM_001180183.1_VR1 | cds-NP_010159.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:239313-240251:+ | gene-YDL124W_ZTW1 | rna-NM_001180183.1_ZTW1 | cds-NP_010159.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:241449-242387:+ | gene-YDL124W_Sparadoxus | rna-NM_001180183.1_Sparadoxus | cds-NP_010159.1_Sparadoxus | 88.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |