Gene name: YCK1
Reference locus (S288C): YHR135C
Gene biotype: protein_coding
Description: Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication
Top 10 interactors (score): YCK2 (0.999); RGT2 (0.945); STE2 (0.937); AKR1 (0.898); STE3 (0.892); HEK2 (0.866); STD1 (0.852); CKA1 (0.82); SSY1 (0.801); PTK2 (0.789); KAP123 (0.787); BCP1 (0.783); RDR1 (0.78); GRR1 (0.771); RGT1 (0.77); SNF3 (0.77); RIM11 (0.75); PIN2 (0.745); YPL199C (0.734); SST2 (0.714)
Homologues (species, bitscore): CSNK1G2 (Homo sapiens, 348.6); Csnk1g3 (Mus musculus, 349.0); csnk1g2b (Danio rerio, 348.6); csnk1g3 (Xenopus tropicalis, 350.9); gish (Drosophila melanogaster, 314.3); csnk-1 (Caenorhabditis elegans, 347.1); ckl8 (Arabidopsis thaliana, 315.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:359626-361242:- | gene-YHR135C_AKU4011 | rna-NM_001179265.1_AKU4011 | cds-NP_012003.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:156612-158228:+ | gene-YHR135C_BG1 | rna-NM_001179265.1_BG1 | cds-NP_012003.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:366843-368459:- | gene-YHR135C_Bruggeman | rna-NM_001179265.1_Bruggeman | cds-NP_012003.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:362042-363658:- | gene-YHR135C_CAT1 | rna-NM_001179265.1_CAT1 | cds-NP_012003.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:358648-360264:- | gene-YHR135C_CBS1585 | rna-NM_001179265.1_CBS1585 | cds-NP_012003.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:356001-357617:- | gene-YHR135C_CBS436 | rna-NM_001179265.1_CBS436 | cds-NP_012003.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:360089-361705:- | gene-YHR135C_CBS6412 | rna-NM_001179265.1_CBS6412 | cds-NP_012003.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:359678-361294:- | gene-YHR135C_CBS6413 | rna-NM_001179265.1_CBS6413 | cds-NP_012003.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:365867-367483:- | gene-YHR135C_CENPK1137D | rna-NM_001179265.1_CENPK1137D | cds-NP_012003.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:418536-420152:- | gene-YHR135C_EthanolRed | rna-NM_001179265.1_EthanolRed | cds-NP_012003.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:360024-361640:- | gene-YHR135C_FaliES1 | rna-NM_001179265.1_FaliES1 | cds-NP_012003.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000275.1:2154-3770:- | gene-YHR135C_JAY291 | rna-NM_001179265.1_JAY291 | cds-NP_012003.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:366573-368189:- | gene-YHR135C_MUCL30387 | rna-NM_001179265.1_MUCL30387 | cds-NP_012003.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:366838-368454:- | gene-YHR135C_MUCL30388 | rna-NM_001179265.1_MUCL30388 | cds-NP_012003.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:358992-360608:- | gene-YHR135C_MUCL39482 | rna-NM_001179265.1_MUCL39482 | cds-NP_012003.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:365205-366821:- | gene-YHR135C_MUCL42920 | rna-NM_001179265.1_MUCL42920 | cds-NP_012003.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:372576-374192:- | gene-YHR135C_NCIM3186 | rna-NM_001179265.1_NCIM3186 | cds-NP_012003.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:361200-362816:- | gene-YHR135C_NCYC1407 | rna-NM_001179265.1_NCYC1407 | cds-NP_012003.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:360641-362257:- | gene-YHR135C_PE2H3 | rna-NM_001179265.1_PE2H3 | cds-NP_012003.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:368068-369684:- | gene-YHR135C_PE2H4 | rna-NM_001179265.1_PE2H4 | cds-NP_012003.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:372694-374310:- | gene-YHR135C_S288C | rna-NM_001179265.1_S288C | cds-NP_012003.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000103.1:15086-16702:+ | gene-YHR135C_SA1 | rna-NM_001179265.1_SA1 | cds-NP_012003.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:361107-362723:- | gene-YHR135C_ThermosaccDry | rna-NM_001179265.1_ThermosaccDry | cds-NP_012003.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:369551-371167:- | gene-YHR135C_VR1 | rna-NM_001179265.1_VR1 | cds-NP_012003.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:352105-353721:- | gene-YHR135C_ZTW1 | rna-NM_001179265.1_ZTW1 | cds-NP_012003.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:358563-360170:- | gene-YHR135C_Sparadoxus | rna-NM_001179265.1_Sparadoxus | cds-NP_012003.1_Sparadoxus | 89.8 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |