Gene name: YAP1
Reference locus (S288C): YML007W
Gene biotype: protein_coding
Description: Basic leucine zipper (bZIP) transcription factor; required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; Yap1p is degraded in the nucleus after the oxidative stress has passed; mediates resistance to cadmium; relative distribution to the nucleus increases upon DNA replication stress; YAP1 has a paralog, CAD1, that arose from the whole genome duplication
Top 10 interactors (score): SKO1 (0.999); SKN7 (0.996); YBP1 (0.994); CRM1 (0.988); HYR1 (0.981); TSA1 (0.98); HSF1 (0.977); TRX2 (0.972); TRX1 (0.964); TRR1 (0.961); FLR1 (0.952); GLR1 (0.942); HOG1 (0.942); MSN2 (0.938); ARR1 (0.938); GSH1 (0.916); RPN4 (0.915); CTT1 (0.912); MSN4 (0.895); CTA1 (0.893)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:303401-305371:+ | gene-YML007W_AKU4011 | rna-NM_001182362.1_AKU4011 | cds-NP_013707.1_AKU4011 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:237457-239409:- | gene-YML007W_BG1 | rna-NM_001182362.1_BG1 | cds-NP_013707.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:243384-245336:+ | gene-YML007W_Bruggeman | rna-NM_001182362.1_Bruggeman | cds-NP_013707.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:245897-247849:+ | gene-YML007W_CAT1 | rna-NM_001182362.1_CAT1 | cds-NP_013707.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:236380-238350:+ | gene-YML007W_CBS1585 | rna-NM_001182362.1_CBS1585 | cds-NP_013707.1_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:241912-243882:+ | gene-YML007W_CBS436 | rna-NM_001182362.1_CBS436 | cds-NP_013707.1_CBS436 | 98.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:350113-352119:+ | gene-YML007W_CBS6412 | rna-NM_001182362.1_CBS6412 | cds-NP_013707.1_CBS6412 | 97.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:235635-237605:+ | gene-YML007W_CBS6413 | rna-NM_001182362.1_CBS6413 | cds-NP_013707.1_CBS6413 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:248579-250531:+ | gene-YML007W_CENPK1137D | rna-NM_001182362.1_CENPK1137D | cds-NP_013707.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:236415-238385:+ | gene-YML007W_EthanolRed | rna-NM_001182362.1_EthanolRed | cds-NP_013707.1_EthanolRed | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:239381-241351:+ | gene-YML007W_FaliES1 | rna-NM_001182362.1_FaliES1 | cds-NP_013707.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:195590-197542:- | gene-YML007W_JAY291 | rna-NM_001182362.1_JAY291 | cds-NP_013707.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:241120-243067:+ | gene-YML007W_MUCL30387 | rna-NM_001182362.1_MUCL30387 | cds-NP_013707.1_MUCL30387 | 99.4 | 99.7 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:245781-247733:+ | gene-YML007W_MUCL30388 | rna-NM_001182362.1_MUCL30388 | cds-NP_013707.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:236660-238630:+ | gene-YML007W_MUCL39482 | rna-NM_001182362.1_MUCL39482 | cds-NP_013707.1_MUCL39482 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:242227-244179:+ | gene-YML007W_MUCL42920 | rna-NM_001182362.1_MUCL42920 | cds-NP_013707.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:253802-255754:+ | gene-YML007W_NCIM3186 | rna-NM_001182362.1_NCIM3186 | cds-NP_013707.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:236595-238565:+ | gene-YML007W_NCYC1407 | rna-NM_001182362.1_NCYC1407 | cds-NP_013707.1_NCYC1407 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:242531-244483:+ | gene-YML007W_PE2H3 | rna-NM_001182362.1_PE2H3 | cds-NP_013707.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:248626-250578:+ | gene-YML007W_PE2H4 | rna-NM_001182362.1_PE2H4 | cds-NP_013707.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:253848-255800:+ | gene-YML007W_S288C | rna-NM_001182362.1_S288C | cds-NP_013707.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:282477-284429:- | gene-YML007W_SA1 | rna-NM_001182362.1_SA1 | cds-NP_013707.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:236443-238413:+ | gene-YML007W_ThermosaccDry | rna-NM_001182362.1_ThermosaccDry | cds-NP_013707.1_ThermosaccDry | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:240418-242370:+ | gene-YML007W_VR1 | rna-NM_001182362.1_VR1 | cds-NP_013707.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:215502-217454:+ | gene-YML007W_ZTW1 | rna-NM_001182362.1_ZTW1 | cds-NP_013707.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:247171-249168:+ | gene-YML007W_Sparadoxus | rna-NM_001182362.1_Sparadoxus | cds-NP_013707.1_Sparadoxus | 85.0 | 98.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |