XBP1 (YIL101C)


Gene profile

Gene name: XBP1
Reference locus (S288C): YIL101C
Gene biotype: protein_coding

Description: Transcriptional repressor; binds promoter sequences of cyclin genes, CYS3, and SMF2; not expressed during log phase of growth, but induced by stress or starvation during mitosis, and late in meiosis; represses 15% of all yeast genes as cells transition to quiescence; important for maintaining G1 arrest and for longevity of quiescent cells; member of Swi4p/Mbp1p family; phosphorylated by Cdc28p; relative distribution to nucleus increases upon DNA replication stress

Top 10 interactors (score): DDR2 (0.967); USV1 (0.927); MSC1 (0.921); SOL4 (0.896); OM45 (0.887); CTT1 (0.881); TSL1 (0.868); DCS2 (0.867); SWI4 (0.864); MBP1 (0.855); PHM7 (0.848); RTN2 (0.843); BDH2 (0.831); GAD1 (0.825); GLC3 (0.817); TFS1 (0.811); PGM2 (0.788); SWI6 (0.775); RTC3 (0.772); ALD3 (0.769)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:176743-178686:- gene-YIL101C_AKU4011 rna-NM_001179449.1_AKU4011 cds-NP_012165.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:39750-41693:- gene-YIL101C_BG1 rna-NM_001179449.1_BG1 cds-NP_012165.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:181441-183387:- gene-YIL101C_Bruggeman rna-NM_001179449.1_Bruggeman cds-NP_012165.1_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:173491-175434:- gene-YIL101C_CAT1 rna-NM_001179449.1_CAT1 cds-NP_012165.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:176999-178942:- gene-YIL101C_CBS1585 rna-NM_001179449.1_CBS1585 cds-NP_012165.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:167988-169931:- gene-YIL101C_CBS436 rna-NM_001179449.1_CBS436 cds-NP_012165.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:174379-176322:- gene-YIL101C_CBS6412 rna-NM_001179449.1_CBS6412 cds-NP_012165.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:168032-169975:- gene-YIL101C_CBS6413 rna-NM_001179449.1_CBS6413 cds-NP_012165.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:167020-168963:- gene-YIL101C_CENPK1137D rna-NM_001179449.1_CENPK1137D cds-NP_012165.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:161964-163907:- gene-YIL101C_EthanolRed rna-NM_001179449.1_EthanolRed cds-NP_012165.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:177959-179902:- gene-YIL101C_FaliES1 rna-NM_001179449.1_FaliES1 cds-NP_012165.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000025.1:48567-50510:+ gene-YIL101C_JAY291 rna-NM_001179449.1_JAY291 cds-NP_012165.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:179165-181111:- gene-YIL101C_MUCL30387 rna-NM_001179449.1_MUCL30387 cds-NP_012165.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:176956-178902:- gene-YIL101C_MUCL30388 rna-NM_001179449.1_MUCL30388 cds-NP_012165.1_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:177845-179788:- gene-YIL101C_MUCL39482 rna-NM_001179449.1_MUCL39482 cds-NP_012165.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:181097-183040:- gene-YIL101C_MUCL42920 rna-NM_001179449.1_MUCL42920 cds-NP_012165.1_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:175307-177250:- gene-YIL101C_NCIM3186 rna-NM_001179449.1_NCIM3186 cds-NP_012165.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:181888-183831:- gene-YIL101C_NCYC1407 rna-NM_001179449.1_NCYC1407 cds-NP_012165.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:176449-178392:- gene-YIL101C_PE2H3 rna-NM_001179449.1_PE2H3 cds-NP_012165.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:170400-172343:- gene-YIL101C_PE2H4 rna-NM_001179449.1_PE2H4 cds-NP_012165.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:175307-177250:- gene-YIL101C_S288C rna-NM_001179449.1_S288C cds-NP_012165.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000058.1:6098-8041:+ gene-YIL101C_SA1 rna-NM_001179449.1_SA1 cds-NP_012165.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:176628-178571:- gene-YIL101C_ThermosaccDry rna-NM_001179449.1_ThermosaccDry cds-NP_012165.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:173597-175549:- gene-YIL101C_VR1 rna-NM_001179449.1_VR1 cds-NP_012165.1_VR1 98.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:151562-153505:- gene-YIL101C_ZTW1 rna-NM_001179449.1_ZTW1 cds-NP_012165.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:175494-177419:- gene-YIL101C_Sparadoxus rna-NM_001179449.1_Sparadoxus cds-NP_012165.1_Sparadoxus 86.8 98.8 Verified 1 1 1 False True False False False

Additional files