Gene name: WSS1
Reference locus (S288C): YHR134W
Gene biotype: protein_coding
Description: DNA-dependent metalloprotease WSS1; SUMO-ligase and SUMO-targeted metalloprotease; involved in DNA repair; removes DNA-protein crosslinks at stalled replication forks during replication of damaged DNA; clears chromatin-bound sumoylated proteins; localizes to single spot on nuclear periphery of mother cells but not daughters; exhibits vacuolar localization upon genotoxic stress; activated by DNA binding; member of minigluzincins protease family with mammalian DVC1/Spartan; Belongs to the peptidase M3 family. WSS1-like metalloprotease (WLM) subfamily
Top 10 interactors (score): SMT3 (0.962); TDP1 (0.96); CDC48 (0.918); SGS1 (0.888); SLX5 (0.856); NFI1 (0.835); ULP1 (0.814); PSY2 (0.793); ULP2 (0.787); KAR9 (0.778); BIK1 (0.77); RAD52 (0.762); UBC9 (0.758); TOP1 (0.757); SLX8 (0.729); UBP16 (0.696); BIM1 (0.694); LIN1 (0.678); ULS1 (0.676); DOA1 (0.674)
Homologues (species, bitscore): AT1G55915 (Arabidopsis thaliana, 120.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:358682-359491:+ | gene-YHR134W_AKU4011 | rna-NM_001179264.1_AKU4011 | cds-NP_012002.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:158364-159173:- | gene-YHR134W_BG1 | rna-NM_001179264.1_BG1 | cds-NP_012002.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:365898-366707:+ | gene-YHR134W_Bruggeman | rna-NM_001179264.1_Bruggeman | cds-NP_012002.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:361097-361906:+ | gene-YHR134W_CAT1 | rna-NM_001179264.1_CAT1 | cds-NP_012002.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:357704-358513:+ | gene-YHR134W_CBS1585 | rna-NM_001179264.1_CBS1585 | cds-NP_012002.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:355056-355865:+ | gene-YHR134W_CBS436 | rna-NM_001179264.1_CBS436 | cds-NP_012002.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:359145-359954:+ | gene-YHR134W_CBS6412 | rna-NM_001179264.1_CBS6412 | cds-NP_012002.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:358734-359543:+ | gene-YHR134W_CBS6413 | rna-NM_001179264.1_CBS6413 | cds-NP_012002.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:364922-365731:+ | gene-YHR134W_CENPK1137D | rna-NM_001179264.1_CENPK1137D | cds-NP_012002.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:417592-418401:+ | gene-YHR134W_EthanolRed | rna-NM_001179264.1_EthanolRed | cds-NP_012002.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:359080-359889:+ | gene-YHR134W_FaliES1 | rna-NM_001179264.1_FaliES1 | cds-NP_012002.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000275.1:1209-2018:+ | gene-YHR134W_JAY291 | rna-NM_001179264.1_JAY291 | cds-NP_012002.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:365628-366437:+ | gene-YHR134W_MUCL30387 | rna-NM_001179264.1_MUCL30387 | cds-NP_012002.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:365893-366702:+ | gene-YHR134W_MUCL30388 | rna-NM_001179264.1_MUCL30388 | cds-NP_012002.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:358048-358857:+ | gene-YHR134W_MUCL39482 | rna-NM_001179264.1_MUCL39482 | cds-NP_012002.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:364260-365069:+ | gene-YHR134W_MUCL42920 | rna-NM_001179264.1_MUCL42920 | cds-NP_012002.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:371631-372440:+ | gene-YHR134W_NCIM3186 | rna-NM_001179264.1_NCIM3186 | cds-NP_012002.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:360256-361065:+ | gene-YHR134W_NCYC1407 | rna-NM_001179264.1_NCYC1407 | cds-NP_012002.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:359696-360505:+ | gene-YHR134W_PE2H3 | rna-NM_001179264.1_PE2H3 | cds-NP_012002.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:367123-367932:+ | gene-YHR134W_PE2H4 | rna-NM_001179264.1_PE2H4 | cds-NP_012002.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:371749-372558:+ | gene-YHR134W_S288C | rna-NM_001179264.1_S288C | cds-NP_012002.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000103.1:16838-17647:- | gene-YHR134W_SA1 | rna-NM_001179264.1_SA1 | cds-NP_012002.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:360163-360972:+ | gene-YHR134W_ThermosaccDry | rna-NM_001179264.1_ThermosaccDry | cds-NP_012002.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:368606-369415:+ | gene-YHR134W_VR1 | rna-NM_001179264.1_VR1 | cds-NP_012002.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:351161-351970:+ | gene-YHR134W_ZTW1 | rna-NM_001179264.1_ZTW1 | cds-NP_012002.1_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:357610-358429:+ | gene-YHR134W_Sparadoxus | rna-NM_001179264.1_Sparadoxus | cds-NP_012002.1_Sparadoxus | 85.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |