WSC4 (YHL028W)


Gene profile

Gene name: WSC4
Reference locus (S288C): YHL028W
Gene biotype: protein_coding

Description: Cell wall integrity and stress response component 4; Endoplasmic reticulum (ER) membrane protein; involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3

Top 10 interactors (score): RPI1 (0.702); KTR7 (0.699); MID2 (0.626); GYP8 (0.57); MTL1 (0.569); PKC1 (0.55); DAL4 (0.53); SLG1 (0.53); DAL5 (0.526); USB1 (0.483); SDS22 (0.453); ILV3 (0.452); TSR1 (0.451); MET13 (0.451); SPO75 (0.45); FUN19 (0.45); RKR1 (0.45); GAC1 (0.45); BCK1 (0.437); RHO2 (0.403)

Homologues (species, bitscore): COL27A1 (Homo sapiens, 55.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:43611-45461:+ gene-YHL028W_AKU4011 rna-NM_001179108.1_AKU4011 cds-NP_011835.1_AKU4011 97.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000180.1:31311-33161:- gene-YHL028W_BG1 rna-NM_001179108.1_BG1 cds-NP_011835.1_BG1 97.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:50268-52118:+ gene-YHL028W_Bruggeman rna-NM_001179108.1_Bruggeman cds-NP_011835.1_Bruggeman 97.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:44536-46334:+ gene-YHL028W_CAT1 rna-NM_001179108.1_CAT1 cds-NP_011835.1_CAT1 98.2 98.9 Unannotated 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:44212-46062:+ gene-YHL028W_CBS1585 rna-NM_001179108.1_CBS1585 cds-NP_011835.1_CBS1585 97.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:36787-38604:+ gene-YHL028W_CBS436 rna-NM_001179108.1_CBS436 cds-NP_011835.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:44162-46012:+ gene-YHL028W_CBS6412 rna-NM_001179108.1_CBS6412 cds-NP_011835.1_CBS6412 97.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:43625-45475:+ gene-YHL028W_CBS6413 rna-NM_001179108.1_CBS6413 cds-NP_011835.1_CBS6413 97.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:41924-43741:+ gene-YHL028W_CENPK1137D rna-NM_001179108.1_CENPK1137D cds-NP_011835.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:43837-45693:+ gene-YHL028W_EthanolRed rna-NM_001179108.1_EthanolRed cds-NP_011835.1_EthanolRed 96.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:44159-46009:+ gene-YHL028W_FaliES1 rna-NM_001179108.1_FaliES1 cds-NP_011835.1_FaliES1 97.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000003.1:12854-14704:+ gene-YHL028W_JAY291 rna-NM_001179108.1_JAY291 cds-NP_011835.1_JAY291 97.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:46107-47957:+ gene-YHL028W_MUCL30387 rna-NM_001179108.1_MUCL30387 cds-NP_011835.1_MUCL30387 97.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:47944-49794:+ gene-YHL028W_MUCL30388 rna-NM_001179108.1_MUCL30388 cds-NP_011835.1_MUCL30388 97.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:43203-45053:+ gene-YHL028W_MUCL39482 rna-NM_001179108.1_MUCL39482 cds-NP_011835.1_MUCL39482 97.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:47188-49038:+ gene-YHL028W_MUCL42920 rna-NM_001179108.1_MUCL42920 cds-NP_011835.1_MUCL42920 97.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:48645-50462:+ gene-YHL028W_NCIM3186 rna-NM_001179108.1_NCIM3186 cds-NP_011835.1_NCIM3186 98.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:42688-44538:+ gene-YHL028W_NCYC1407 rna-NM_001179108.1_NCYC1407 cds-NP_011835.1_NCYC1407 97.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:38961-40775:+ gene-YHL028W_PE2H3 rna-NM_001179108.1_PE2H3 cds-NP_011835.1_PE2H3 98.5 99.8 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:46366-48216:+ gene-YHL028W_PE2H4 rna-NM_001179108.1_PE2H4 cds-NP_011835.1_PE2H4 97.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:48763-50580:+ gene-YHL028W_S288C rna-NM_001179108.1_S288C cds-NP_011835.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:33032-34876:+ gene-YHL028W_SA1 rna-NM_001179108.1_SA1 cds-NP_011835.1_SA1 97.9 99.8 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:45248-47104:+ gene-YHL028W_ThermosaccDry rna-NM_001179108.1_ThermosaccDry cds-NP_011835.1_ThermosaccDry 96.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:49966-51816:+ gene-YHL028W_VR1 rna-NM_001179108.1_VR1 cds-NP_011835.1_VR1 97.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:36472-38322:+ gene-YHL028W_ZTW1 rna-NM_001179108.1_ZTW1 cds-NP_011835.1_ZTW1 97.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:42791-44623:+ gene-YHL028W_Sparadoxus rna-NM_001179108.1_Sparadoxus cds-NP_011835.1_Sparadoxus 82.6 98.6 Verified 1 1 1 False True False False False

Additional files