Gene name: WSC3
Reference locus (S288C): YOL105C
Gene biotype: protein_coding
Description: Cell wall integrity and stress response component 3; Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway; involved in maintenance of cell wall integrity; involved in response to heat shock and other stressors; regulates 1,3-beta-glucan synthesis; WSC3 has a paralog, WSC2, that arose from the whole genome duplication
Top 10 interactors (score): WSC2 (0.963); ROM2 (0.954); MID2 (0.943); ROM1 (0.937); MTL1 (0.913); SLG1 (0.895); PKC1 (0.844); RHO1 (0.797); BCK1 (0.781); MKK1 (0.728); SLT2 (0.71); YLR280C (0.696); RLM1 (0.694); FKS1 (0.676); YNL190W (0.676); FOL1 (0.674); RPC11 (0.659); LRE1 (0.612); IMD4 (0.596); MKK2 (0.592)
Homologues (species, bitscore): Wscd1 (Mus musculus, 51.2); RKL1 (Arabidopsis thaliana, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:103362-105056:- | gene-YOL105C_AKU4011 | rna-NM_001183359.1_AKU4011 | cds-NP_014536.1_AKU4011 | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:68417-70099:- | gene-YOL105C_BG1 | rna-NM_001183359.1_BG1 | cds-NP_014536.1_BG1 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:104931-106637:- | gene-YOL105C_Bruggeman | rna-NM_001183359.1_Bruggeman | cds-NP_014536.1_Bruggeman | 96.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:103793-105511:- | gene-YOL105C_CAT1 | rna-NM_001183359.1_CAT1 | cds-NP_014536.1_CAT1 | 96.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:97819-99495:- | gene-YOL105C_CBS1585 | rna-NM_001183359.1_CBS1585 | cds-NP_014536.1_CBS1585 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:103093-104775:- | gene-YOL105C_CBS436 | rna-NM_001183359.1_CBS436 | cds-NP_014536.1_CBS436 | 98.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:97963-99657:- | gene-YOL105C_CBS6412 | rna-NM_001183359.1_CBS6412 | cds-NP_014536.1_CBS6412 | 97.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:104664-106358:- | gene-YOL105C_CBS6413 | rna-NM_001183359.1_CBS6413 | cds-NP_014536.1_CBS6413 | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:114033-115703:- | gene-YOL105C_CENPK1137D | rna-NM_001183359.1_CENPK1137D | cds-NP_014536.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:100977-102659:- | gene-YOL105C_EthanolRed | rna-NM_001183359.1_EthanolRed | cds-NP_014536.1_EthanolRed | 97.8 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:103195-104986:- | gene-YOL105C_FaliES1 | rna-NM_001183359.1_FaliES1 | cds-NP_014536.1_FaliES1 | 92.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000160.1:38482-40164:+ | gene-YOL105C_JAY291 | rna-NM_001183359.1_JAY291 | cds-NP_014536.1_JAY291 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:108709-110841:- | gene-YOL105C_MUCL30387 | rna-NM_001183359.1_MUCL30387 | cds-NP_014536.1_MUCL30387 | 77.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:112354-114024:- | gene-YOL105C_MUCL30388 | rna-NM_001183359.1_MUCL30388 | cds-NP_014536.1_MUCL30388 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:105723-107417:- | gene-YOL105C_MUCL39482 | rna-NM_001183359.1_MUCL39482 | cds-NP_014536.1_MUCL39482 | 97.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:121471-123189:- | gene-YOL105C_MUCL42920 | rna-NM_001183359.1_MUCL42920 | cds-NP_014536.1_MUCL42920 | 96.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:114027-115697:- | gene-YOL105C_NCIM3186 | rna-NM_001183359.1_NCIM3186 | cds-NP_014536.1_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:112301-114013:- | gene-YOL105C_NCYC1407 | rna-NM_001183359.1_NCYC1407 | cds-NP_014536.1_NCYC1407 | 96.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:95632-97314:- | gene-YOL105C_PE2H3 | rna-NM_001183359.1_PE2H3 | cds-NP_014536.1_PE2H3 | 98.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:106632-108290:- | gene-YOL105C_PE2H4 | rna-NM_001183359.1_PE2H4 | cds-NP_014536.1_PE2H4 | 98.2 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:114138-115808:- | gene-YOL105C_S288C | rna-NM_001183359.1_S288C | cds-NP_014536.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:87952-89610:- | gene-YOL105C_SA1 | rna-NM_001183359.1_SA1 | cds-NP_014536.1_SA1 | 98.3 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:102293-103994:- | gene-YOL105C_ThermosaccDry | rna-NM_001183359.1_ThermosaccDry | cds-NP_014536.1_ThermosaccDry | 96.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:102878-104560:- | gene-YOL105C_VR1 | rna-NM_001183359.1_VR1 | cds-NP_014536.1_VR1 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:101975-103693:- | gene-YOL105C_ZTW1 | rna-NM_001183359.1_ZTW1 | cds-NP_014536.1_ZTW1 | 96.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:105444-107087:- | gene-YOL105C_Sparadoxus | rna-NM_001183359.1_Sparadoxus | cds-NP_014536.1_Sparadoxus | 83.5 | 97.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |