Gene name: WHI3
Reference locus (S288C): YNL197C
Gene biotype: protein_coding
Description: RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; regulates genes involved in the cell cycle, sister chromatid cohesion, and stress response; acts as a cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start; Tpk1p (PKA) mediated phosphorylation (S568) inhibits Whi3p function, decreasing its interaction with CLN3 mRNA; regulates ploidy
Top 10 interactors (score): WHI4 (0.999); CLN3 (0.989); PUF2 (0.914); VPS51 (0.902); PUF4 (0.872); DED1 (0.836); PUB1 (0.815); HEK2 (0.802); PUF3 (0.802); WHI5 (0.78); YDJ1 (0.767); POP2 (0.748); CDC28 (0.748); TIF4631 (0.735); BCK2 (0.716); BNI1 (0.715); SFP1 (0.7); NGR1 (0.7); NRM1 (0.699); ECL1 (0.694)
Homologues (species, bitscore): mec-8 (Caenorhabditis elegans, 63.2); AT3G21215 (Arabidopsis thaliana, 77.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:261383-263368:- | gene-YNL197C_AKU4011 | rna-NM_001183035.1_AKU4011 | cds-NP_014202.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:165333-167318:- | gene-YNL197C_BG1 | rna-NM_001183035.1_BG1 | cds-NP_014202.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:271432-273417:- | gene-YNL197C_Bruggeman | rna-NM_001183035.1_Bruggeman | cds-NP_014202.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:313674-315659:- | gene-YNL197C_CAT1 | rna-NM_001183035.1_CAT1 | cds-NP_014202.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:262028-264013:- | gene-YNL197C_CBS1585 | rna-NM_001183035.1_CBS1585 | cds-NP_014202.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:330317-332302:- | gene-YNL197C_CBS436 | rna-NM_001183035.1_CBS436 | cds-NP_014202.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:257442-259427:- | gene-YNL197C_CBS6412 | rna-NM_001183035.1_CBS6412 | cds-NP_014202.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:258462-260447:- | gene-YNL197C_CBS6413 | rna-NM_001183035.1_CBS6413 | cds-NP_014202.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:261456-263441:- | gene-YNL197C_CENPK1137D | rna-NM_001183035.1_CENPK1137D | cds-NP_014202.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:258352-260337:- | gene-YNL197C_EthanolRed | rna-NM_001183035.1_EthanolRed | cds-NP_014202.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:254265-256250:- | gene-YNL197C_FaliES1 | rna-NM_001183035.1_FaliES1 | cds-NP_014202.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000260.1:62117-64102:+ | gene-YNL197C_JAY291 | rna-NM_001183035.1_JAY291 | cds-NP_014202.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:267219-269204:- | gene-YNL197C_MUCL30387 | rna-NM_001183035.1_MUCL30387 | cds-NP_014202.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:301585-303570:- | gene-YNL197C_MUCL30388 | rna-NM_001183035.1_MUCL30388 | cds-NP_014202.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:259267-261252:- | gene-YNL197C_MUCL39482 | rna-NM_001183035.1_MUCL39482 | cds-NP_014202.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:261635-263620:- | gene-YNL197C_MUCL42920 | rna-NM_001183035.1_MUCL42920 | cds-NP_014202.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:267577-269562:- | gene-YNL197C_NCIM3186 | rna-NM_001183035.1_NCIM3186 | cds-NP_014202.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:261357-263342:- | gene-YNL197C_NCYC1407 | rna-NM_001183035.1_NCYC1407 | cds-NP_014202.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:258270-260255:- | gene-YNL197C_PE2H3 | rna-NM_001183035.1_PE2H3 | cds-NP_014202.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:257658-259643:- | gene-YNL197C_PE2H4 | rna-NM_001183035.1_PE2H4 | cds-NP_014202.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:267608-269593:- | gene-YNL197C_S288C | rna-NM_001183035.1_S288C | cds-NP_014202.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000018.1:144006-145991:+ | gene-YNL197C_SA1 | rna-NM_001183035.1_SA1 | cds-NP_014202.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:255122-257107:- | gene-YNL197C_ThermosaccDry | rna-NM_001183035.1_ThermosaccDry | cds-NP_014202.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:273624-275609:- | gene-YNL197C_VR1 | rna-NM_001183035.1_VR1 | cds-NP_014202.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:164951-166936:- | gene-YNL197C_ZTW1 | rna-NM_001183035.1_ZTW1 | cds-NP_014202.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:265467-267470:- | gene-YNL197C_Sparadoxus | rna-NM_001183035.1_Sparadoxus | cds-NP_014202.1_Sparadoxus | 89.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |