WBP1 (YEL002C)


Gene profile

Gene name: WBP1
Reference locus (S288C): YEL002C
Gene biotype: protein_coding

Description: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Beta subunit of the oligosaccharyl transferase glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum; human homolog DDOST can complement yeast growth defect during down-regulation of yeast gene; Belongs to the DDOST 48 kDa subunit family

Top 10 interactors (score): OST5 (0.999); SBH1 (0.999); OST6 (0.999); SWP1 (0.999); OST2 (0.999); STT3 (0.999); OST4 (0.999); OST3 (0.999); OST1 (0.999); CNE1 (0.998); SEC61 (0.997); SBH2 (0.993); DIE2 (0.99); CWH41 (0.982); KAR2 (0.979); SEC63 (0.975); LHS1 (0.972); YPF1 (0.969); ERD2 (0.965); PDI1 (0.958)

Homologues (species, bitscore): DDOST (Homo sapiens, 120.6); Ddost (Mus musculus, 117.5); ddost (Danio rerio, 120.2); ddost (Xenopus tropicalis, 91.7); Ost48 (Drosophila melanogaster, 111.3); ostb-1 (Caenorhabditis elegans, 120.9); DGL1 (Arabidopsis thaliana, 117.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:142403-143695:- gene-YEL002C_AKU4011 rna-NM_001178817.3_AKU4011 cds-NP_010914.3_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:281975-283267:+ gene-YEL002C_BG1 rna-NM_001178817.3_BG1 cds-NP_010914.3_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:148935-150227:- gene-YEL002C_Bruggeman rna-NM_001178817.3_Bruggeman cds-NP_010914.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:145333-146625:- gene-YEL002C_CAT1 rna-NM_001178817.3_CAT1 cds-NP_010914.3_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:142712-144004:- gene-YEL002C_CBS1585 rna-NM_001178817.3_CBS1585 cds-NP_010914.3_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:143991-145283:- gene-YEL002C_CBS436 rna-NM_001178817.3_CBS436 cds-NP_010914.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:142606-143898:- gene-YEL002C_CBS6412 rna-NM_001178817.3_CBS6412 cds-NP_010914.3_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:147254-148546:- gene-YEL002C_CBS6413 rna-NM_001178817.3_CBS6413 cds-NP_010914.3_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:146549-147841:- gene-YEL002C_CENPK1137D rna-NM_001178817.3_CENPK1137D cds-NP_010914.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:143068-144360:- gene-YEL002C_EthanolRed rna-NM_001178817.3_EthanolRed cds-NP_010914.3_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:143327-144619:- gene-YEL002C_FaliES1 rna-NM_001178817.3_FaliES1 cds-NP_010914.3_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000024.1:10308-11600:- gene-YEL002C_JAY291 rna-NM_001178817.3_JAY291 cds-NP_010914.3_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:146637-147929:- gene-YEL002C_MUCL30387 rna-NM_001178817.3_MUCL30387 cds-NP_010914.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:143158-144450:- gene-YEL002C_MUCL30388 rna-NM_001178817.3_MUCL30388 cds-NP_010914.3_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:141748-143040:- gene-YEL002C_MUCL39482 rna-NM_001178817.3_MUCL39482 cds-NP_010914.3_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:146344-147636:- gene-YEL002C_MUCL42920 rna-NM_001178817.3_MUCL42920 cds-NP_010914.3_MUCL42920 99.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:148721-150013:- gene-YEL002C_NCIM3186 rna-NM_001178817.3_NCIM3186 cds-NP_010914.3_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:146824-148116:- gene-YEL002C_NCYC1407 rna-NM_001178817.3_NCYC1407 cds-NP_010914.3_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:151135-152427:- gene-YEL002C_PE2H3 rna-NM_001178817.3_PE2H3 cds-NP_010914.3_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:147050-148342:- gene-YEL002C_PE2H4 rna-NM_001178817.3_PE2H4 cds-NP_010914.3_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:148722-150014:- gene-YEL002C_S288C rna-NM_001178817.3_S288C cds-NP_010914.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:93577-94869:+ gene-YEL002C_SA1 rna-NM_001178817.3_SA1 cds-NP_010914.3_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:143733-145025:- gene-YEL002C_ThermosaccDry rna-NM_001178817.3_ThermosaccDry cds-NP_010914.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:143226-144518:- gene-YEL002C_VR1 rna-NM_001178817.3_VR1 cds-NP_010914.3_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:141761-143053:- gene-YEL002C_ZTW1 rna-NM_001178817.3_ZTW1 cds-NP_010914.3_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:146439-147731:- gene-YEL002C_Sparadoxus rna-NM_001178817.3_Sparadoxus cds-NP_010914.3_Sparadoxus 91.3 100.0 Verified 1 1 1 False True False False False

Additional files