VTS1 (YOR359W)


Gene profile

Gene name: VTS1
Reference locus (S288C): YOR359W
Gene biotype: protein_coding

Description: Protein VTS1; Flap-structured DNA-binding and RNA-binding protein; stimulates deadenylation-dependent mRNA degradation mediated by the CCR4-NOT deadenylase complex; member of the Smaug (Smg) family of post-transcriptional regulators which bind RNA through a conserved sterile alpha motif (SAM) domain that interacts with Smg recognition element (SREs) containing transcripts; stimulates Dna2p endonuclease activity

Top 10 interactors (score): PAB1 (0.969); PUF3 (0.917); MPT5 (0.88); NOG2 (0.82); HEK2 (0.812); HMT1 (0.801); CCR4 (0.784); PUF4 (0.774); UTP15 (0.757); TOD6 (0.746); NOG1 (0.73); YLL032C (0.727); DHH1 (0.724); GIS2 (0.717); SCD6 (0.713); PFS2 (0.707); PUB1 (0.703); PUF2 (0.69); TCP1 (0.673); TDA3 (0.669)

Homologues (species, bitscore): SAMD4B (Homo sapiens, 50.8); Pak4 (Mus musculus, 50.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:997773-999344:+ gene-YOR359W_AKU4011 rna-NM_001183779.3_AKU4011 cds-NP_015004.3_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000078.1:34949-36520:+ gene-YOR359W_BG1 rna-NM_001183779.3_BG1 cds-NP_015004.3_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:982590-984161:+ gene-YOR359W_Bruggeman rna-NM_001183779.3_Bruggeman cds-NP_015004.3_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:982418-983989:+ gene-YOR359W_CAT1 rna-NM_001183779.3_CAT1 cds-NP_015004.3_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:982183-983754:+ gene-YOR359W_CBS1585 rna-NM_001183779.3_CBS1585 cds-NP_015004.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:976996-978567:+ gene-YOR359W_CBS436 rna-NM_001183779.3_CBS436 cds-NP_015004.3_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:211485-213056:+ gene-YOR359W_CBS6412 rna-NM_001183779.3_CBS6412 cds-NP_015004.3_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:986456-988027:+ gene-YOR359W_CBS6413 rna-NM_001183779.3_CBS6413 cds-NP_015004.3_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:1011011-1012582:+ gene-YOR359W_CENPK1137D rna-NM_001183779.3_CENPK1137D cds-NP_015004.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:226482-228053:+ gene-YOR359W_EthanolRed rna-NM_001183779.3_EthanolRed cds-NP_015004.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:979311-980882:+ gene-YOR359W_FaliES1 rna-NM_001183779.3_FaliES1 cds-NP_015004.3_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000078.1:24792-26363:- gene-YOR359W_JAY291 rna-NM_001183779.3_JAY291 cds-NP_015004.3_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:991918-993489:+ gene-YOR359W_MUCL30387 rna-NM_001183779.3_MUCL30387 cds-NP_015004.3_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:999943-1001514:+ gene-YOR359W_MUCL30388 rna-NM_001183779.3_MUCL30388 cds-NP_015004.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:988718-990289:+ gene-YOR359W_MUCL39482 rna-NM_001183779.3_MUCL39482 cds-NP_015004.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:996324-997895:+ gene-YOR359W_MUCL42920 rna-NM_001183779.3_MUCL42920 cds-NP_015004.3_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:1011078-1012649:+ gene-YOR359W_NCIM3186 rna-NM_001183779.3_NCIM3186 cds-NP_015004.3_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:989726-991297:+ gene-YOR359W_NCYC1407 rna-NM_001183779.3_NCYC1407 cds-NP_015004.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:984986-986557:+ gene-YOR359W_PE2H3 rna-NM_001183779.3_PE2H3 cds-NP_015004.3_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:1001337-1002908:+ gene-YOR359W_PE2H4 rna-NM_001183779.3_PE2H4 cds-NP_015004.3_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:1011189-1012760:+ gene-YOR359W_S288C rna-NM_001183779.3_S288C cds-NP_015004.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000016.1:115720-117291:+ gene-YOR359W_SA1 rna-NM_001183779.3_SA1 cds-NP_015004.3_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:978481-980052:+ gene-YOR359W_ThermosaccDry rna-NM_001183779.3_ThermosaccDry cds-NP_015004.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:1039736-1041307:+ gene-YOR359W_VR1 rna-NM_001183779.3_VR1 cds-NP_015004.3_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:711211-712782:+ gene-YOR359W_ZTW1 rna-NM_001183779.3_ZTW1 cds-NP_015004.3_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:984673-986259:+ gene-YOR359W_Sparadoxus rna-NM_001183779.3_Sparadoxus cds-NP_015004.3_Sparadoxus 89.5 100.0 Verified 1 1 1 False True False False False

Additional files