Gene name: VTC4
Reference locus (S288C): YJL012C
Gene biotype: protein_coding
Description: Vacuolar transporter chaperone 4; Vacuolar membrane polyphosphate polymerase; subunit of the vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to the vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): VTC3 (0.991); VTC1 (0.97); PHO84 (0.968); VTC5 (0.953); PHO12 (0.944); PHO11 (0.93); SPL2 (0.92); VTC2 (0.876); PHO81 (0.823); PHO80 (0.81); PHO88 (0.786); PHO89 (0.771); CCT8 (0.765); PHO4 (0.763); PPN1 (0.746); TPH3 (0.744); CCT3 (0.738); TCP1 (0.72); CCT6 (0.72); CCT4 (0.72)
Homologues (species, bitscore): XPR1 (Homo sapiens, 55.5); Xpr1 (Mus musculus, 57.0); xpr1a (Danio rerio, 58.5); xpr1 (Xenopus tropicalis, 54.3); CG10483 (Drosophila melanogaster, 53.9); Y39A1A.22 (Caenorhabditis elegans, 53.9); SPX2 (Arabidopsis thaliana, 61.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:394384-396549:- | gene-YJL012C_AKU4011 | rna-NM_001181446.1_AKU4011 | cds-NP_012522.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:217613-219778:+ | gene-YJL012C_BG1 | rna-NM_001181446.1_BG1 | cds-NP_012522.2_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:408472-410637:- | gene-YJL012C_Bruggeman | rna-NM_001181446.1_Bruggeman | cds-NP_012522.2_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:412453-414618:- | gene-YJL012C_CAT1 | rna-NM_001181446.1_CAT1 | cds-NP_012522.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:405973-408138:- | gene-YJL012C_CBS1585 | rna-NM_001181446.1_CBS1585 | cds-NP_012522.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:424349-426514:- | gene-YJL012C_CBS436 | rna-NM_001181446.1_CBS436 | cds-NP_012522.2_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:394198-396363:- | gene-YJL012C_CBS6412 | rna-NM_001181446.1_CBS6412 | cds-NP_012522.2_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:396413-398578:- | gene-YJL012C_CBS6413 | rna-NM_001181446.1_CBS6413 | cds-NP_012522.2_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:393655-395820:- | gene-YJL012C_CENPK1137D | rna-NM_001181446.1_CENPK1137D | cds-NP_012522.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:397257-399422:- | gene-YJL012C_EthanolRed | rna-NM_001181446.1_EthanolRed | cds-NP_012522.2_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:410002-412167:- | gene-YJL012C_FaliES1 | rna-NM_001181446.1_FaliES1 | cds-NP_012522.2_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000200.1:3419-5584:+ | gene-YJL012C_JAY291 | rna-NM_001181446.1_JAY291 | cds-NP_012522.2_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:408811-410976:- | gene-YJL012C_MUCL30387 | rna-NM_001181446.1_MUCL30387 | cds-NP_012522.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:404787-406952:- | gene-YJL012C_MUCL30388 | rna-NM_001181446.1_MUCL30388 | cds-NP_012522.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:399290-401455:- | gene-YJL012C_MUCL39482 | rna-NM_001181446.1_MUCL39482 | cds-NP_012522.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:404744-406909:- | gene-YJL012C_MUCL42920 | rna-NM_001181446.1_MUCL42920 | cds-NP_012522.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:411213-413378:- | gene-YJL012C_NCIM3186 | rna-NM_001181446.1_NCIM3186 | cds-NP_012522.2_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:397203-399368:- | gene-YJL012C_NCYC1407 | rna-NM_001181446.1_NCYC1407 | cds-NP_012522.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:409353-411518:- | gene-YJL012C_PE2H3 | rna-NM_001181446.1_PE2H3 | cds-NP_012522.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:408960-411125:- | gene-YJL012C_PE2H4 | rna-NM_001181446.1_PE2H4 | cds-NP_012522.2_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:411234-413399:- | gene-YJL012C_S288C | rna-NM_001181446.1_S288C | cds-NP_012522.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:206880-209045:- | gene-YJL012C_SA1 | rna-NM_001181446.1_SA1 | cds-NP_012522.2_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:403661-405826:- | gene-YJL012C_ThermosaccDry | rna-NM_001181446.1_ThermosaccDry | cds-NP_012522.2_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:405352-407517:- | gene-YJL012C_VR1 | rna-NM_001181446.1_VR1 | cds-NP_012522.2_VR1 | 99.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:384159-386325:- | gene-YJL012C_ZTW1 | rna-NM_001181446.1_ZTW1 | cds-NP_012522.2_ZTW1 | 99.5 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:409763-411928:- | gene-YJL012C_Sparadoxus | rna-NM_001181446.1_Sparadoxus | cds-NP_012522.2_Sparadoxus | 92.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |