VTC3 (YPL019C)


Gene profile

Gene name: VTC3
Reference locus (S288C): YPL019C
Gene biotype: protein_coding

Description: Regulatory subunit of the vacuolar transporter chaperone (VTC) complex; involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion; VTC3 has a paralog, VTC2, that arose from the whole genome duplication; Belongs to the VTC2/3 family

Top 10 interactors (score): VTC4 (0.991); VTC1 (0.989); PHO84 (0.981); PHO11 (0.977); SPL2 (0.973); PHO12 (0.96); VTC5 (0.94); PHO81 (0.929); VTC2 (0.897); PHM6 (0.896); GDE1 (0.885); PHO5 (0.86); PHO89 (0.764); CCT8 (0.722); CCT6 (0.721); CCT2 (0.721); TCP1 (0.721); CCT4 (0.721); CCT7 (0.721); CCT3 (0.721)

Homologues (species, bitscore): XPR1 (Homo sapiens, 58.5); Xpr1 (Mus musculus, 58.5); xpr1 (Danio rerio, 55.1); xpr1 (Xenopus tropicalis, 57.0); CG7536 (Drosophila melanogaster, 56.6); Y39A1A.22 (Caenorhabditis elegans, 58.9); SPX2 (Arabidopsis thaliana, 58.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:486000-488507:- gene-YPL019C_AKU4011 rna-NM_001183833.1_AKU4011 cds-NP_015306.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:408837-411344:+ gene-YPL019C_BG1 rna-NM_001183833.1_BG1 cds-NP_015306.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:562949-565456:- gene-YPL019C_Bruggeman rna-NM_001183833.1_Bruggeman cds-NP_015306.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:602613-605120:- gene-YPL019C_CAT1 rna-NM_001183833.1_CAT1 cds-NP_015306.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:490072-492579:- gene-YPL019C_CBS1585 rna-NM_001183833.1_CBS1585 cds-NP_015306.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:504199-506706:- gene-YPL019C_CBS436 rna-NM_001183833.1_CBS436 cds-NP_015306.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:494263-496770:- gene-YPL019C_CBS6412 rna-NM_001183833.1_CBS6412 cds-NP_015306.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:486625-489132:- gene-YPL019C_CBS6413 rna-NM_001183833.1_CBS6413 cds-NP_015306.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:514472-516979:- gene-YPL019C_CENPK1137D rna-NM_001183833.1_CENPK1137D cds-NP_015306.1_CENPK1137D 99.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:484364-486871:- gene-YPL019C_EthanolRed rna-NM_001183833.1_EthanolRed cds-NP_015306.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:492194-494701:- gene-YPL019C_FaliES1 rna-NM_001183833.1_FaliES1 cds-NP_015306.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:100795-103302:- gene-YPL019C_JAY291 rna-NM_001183833.1_JAY291 cds-NP_015306.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:503897-506404:- gene-YPL019C_MUCL30387 rna-NM_001183833.1_MUCL30387 cds-NP_015306.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:503005-505512:- gene-YPL019C_MUCL30388 rna-NM_001183833.1_MUCL30388 cds-NP_015306.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:483390-485897:- gene-YPL019C_MUCL39482 rna-NM_001183833.1_MUCL39482 cds-NP_015306.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:542517-545024:- gene-YPL019C_MUCL42920 rna-NM_001183833.1_MUCL42920 cds-NP_015306.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:514494-517001:- gene-YPL019C_NCIM3186 rna-NM_001183833.1_NCIM3186 cds-NP_015306.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:490667-493174:- gene-YPL019C_NCYC1407 rna-NM_001183833.1_NCYC1407 cds-NP_015306.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:497323-499830:- gene-YPL019C_PE2H3 rna-NM_001183833.1_PE2H3 cds-NP_015306.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:496938-499445:- gene-YPL019C_PE2H4 rna-NM_001183833.1_PE2H4 cds-NP_015306.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:514511-517018:- gene-YPL019C_S288C rna-NM_001183833.1_S288C cds-NP_015306.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000076.1:11188-13695:- gene-YPL019C_SA1 rna-NM_001183833.1_SA1 cds-NP_015306.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:491993-494500:- gene-YPL019C_ThermosaccDry rna-NM_001183833.1_ThermosaccDry cds-NP_015306.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:506880-509636:- gene-YPL019C_VR1 rna-NM_001183833.1_VR1 cds-NP_015306.1_VR1 90.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:491279-493786:- gene-YPL019C_ZTW1 rna-NM_001183833.1_ZTW1 cds-NP_015306.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:491230-493737:- gene-YPL019C_Sparadoxus rna-NM_001183833.1_Sparadoxus cds-NP_015306.1_Sparadoxus 92.1 100.0 Verified 1 1 1 False True False False False

Additional files