VTC2 (YFL004W)


Gene profile

Gene name: VTC2
Reference locus (S288C): YFL004W
Gene biotype: protein_coding

Description: Regulatory subunit of the vacuolar transporter chaperone (VTC) complex; involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion; VTC2 has a paralog, VTC3, that arose from the whole genome duplication; Belongs to the VTC2/3 family

Top 10 interactors (score): VTC5 (0.946); VTC3 (0.897); PHO81 (0.889); VTC1 (0.884); VTC4 (0.876); GDE1 (0.86); CCT6 (0.721); CCT3 (0.721); CCT5 (0.721); CCT2 (0.721); CCT4 (0.721); TCP1 (0.721); CCT7 (0.721); CCT8 (0.72); PPN1 (0.693); PHO84 (0.679); PHO8 (0.635); SPL2 (0.621); PHO91 (0.617); PHO11 (0.609)

Homologues (species, bitscore): XPR1 (Homo sapiens, 56.6); Xpr1 (Mus musculus, 56.2); xpr1 (Danio rerio, 58.5); xpr1 (Xenopus tropicalis, 55.8); CG7536 (Drosophila melanogaster, 56.2); Y39A1A.22 (Caenorhabditis elegans, 58.5); SPX2 (Arabidopsis thaliana, 50.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:128220-130706:+ gene-YFL004W_AKU4011 rna-NM_001179962.1_AKU4011 cds-NP_116651.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000079.1:13945-16431:+ gene-YFL004W_BG1 rna-NM_001179962.1_BG1 cds-NP_116651.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:127787-130273:+ gene-YFL004W_Bruggeman rna-NM_001179962.1_Bruggeman cds-NP_116651.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:133774-136260:+ gene-YFL004W_CAT1 rna-NM_001179962.1_CAT1 cds-NP_116651.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:129045-131531:+ gene-YFL004W_CBS1585 rna-NM_001179962.1_CBS1585 cds-NP_116651.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:103717-106203:+ gene-YFL004W_CBS436 rna-NM_001179962.1_CBS436 cds-NP_116651.1_CBS436 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:128786-131272:+ gene-YFL004W_CBS6412 rna-NM_001179962.1_CBS6412 cds-NP_116651.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:131296-133782:+ gene-YFL004W_CBS6413 rna-NM_001179962.1_CBS6413 cds-NP_116651.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:128095-130581:+ gene-YFL004W_CENPK1137D rna-NM_001179962.1_CENPK1137D cds-NP_116651.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:127206-129692:+ gene-YFL004W_EthanolRed rna-NM_001179962.1_EthanolRed cds-NP_116651.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:128853-131339:+ gene-YFL004W_FaliES1 rna-NM_001179962.1_FaliES1 cds-NP_116651.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000450.1:13860-16346:+ gene-YFL004W_JAY291 rna-NM_001179962.1_JAY291 cds-NP_116651.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:129417-131903:+ gene-YFL004W_MUCL30387 rna-NM_001179962.1_MUCL30387 cds-NP_116651.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:127390-129876:+ gene-YFL004W_MUCL30388 rna-NM_001179962.1_MUCL30388 cds-NP_116651.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:127489-129975:+ gene-YFL004W_MUCL39482 rna-NM_001179962.1_MUCL39482 cds-NP_116651.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:126753-129239:+ gene-YFL004W_MUCL42920 rna-NM_001179962.1_MUCL42920 cds-NP_116651.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:131809-134295:+ gene-YFL004W_NCIM3186 rna-NM_001179962.1_NCIM3186 cds-NP_116651.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:128504-130990:+ gene-YFL004W_NCYC1407 rna-NM_001179962.1_NCYC1407 cds-NP_116651.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:148394-150880:+ gene-YFL004W_PE2H3 rna-NM_001179962.1_PE2H3 cds-NP_116651.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:147942-150428:+ gene-YFL004W_PE2H4 rna-NM_001179962.1_PE2H4 cds-NP_116651.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:131810-134296:+ gene-YFL004W_S288C rna-NM_001179962.1_S288C cds-NP_116651.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:183141-185627:- gene-YFL004W_SA1 rna-NM_001179962.1_SA1 cds-NP_116651.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:128013-130499:+ gene-YFL004W_ThermosaccDry rna-NM_001179962.1_ThermosaccDry cds-NP_116651.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:137904-140390:+ gene-YFL004W_VR1 rna-NM_001179962.1_VR1 cds-NP_116651.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:58462-60948:+ gene-YFL004W_ZTW1 rna-NM_001179962.1_ZTW1 cds-NP_116651.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:152524-155010:+ gene-YFL004W_Sparadoxus rna-NM_001179962.1_Sparadoxus cds-NP_116651.1_Sparadoxus 92.1 100.0 Verified 1 1 1 False True False False False

Additional files