Gene name: VPS9
Reference locus (S288C): YML097C
Gene biotype: protein_coding
Description: Vacuolar protein sorting-associated protein 9; Guanine nucleotide exchange factor (GEF) and ubiquitin receptor; involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a Ub-interacting CUE domain
Top 10 interactors (score): VPS21 (0.999); YPT52 (0.999); YPT53 (0.996); UBI4 (0.993); YPT10 (0.991); MUK1 (0.978); YPT7 (0.971); MRS6 (0.965); GDI1 (0.964); MON1 (0.964); RPS31 (0.962); VPS29 (0.957); PEP7 (0.942); VPS45 (0.931); SEC4 (0.915); VPS35 (0.911); YPT6 (0.902); YPT1 (0.89); VAM6 (0.872); VPS3 (0.868)
Homologues (species, bitscore): RABGEF1 (Homo sapiens, 109.4); Rabgef1 (Mus musculus, 108.6); rabgef1 (Danio rerio, 108.2); rabgef1 (Xenopus tropicalis, 115.9); Rabex-5 (Drosophila melanogaster, 85.9); rabx-5 (Caenorhabditis elegans, 75.9); VPS9A (Arabidopsis thaliana, 129.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:72056-73411:- | gene-YML097C_AKU4011 | rna-NM_001182457.1_AKU4011 | cds-NP_013612.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:402717-404072:+ | gene-YML097C_BG1 | rna-NM_001182457.1_BG1 | cds-NP_013612.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:78310-79665:- | gene-YML097C_Bruggeman | rna-NM_001182457.1_Bruggeman | cds-NP_013612.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:79869-81224:- | gene-YML097C_CAT1 | rna-NM_001182457.1_CAT1 | cds-NP_013612.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:72058-73413:- | gene-YML097C_CBS1585 | rna-NM_001182457.1_CBS1585 | cds-NP_013612.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:78049-79404:- | gene-YML097C_CBS436 | rna-NM_001182457.1_CBS436 | cds-NP_013612.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:72821-74176:- | gene-YML097C_CBS6412 | rna-NM_001182457.1_CBS6412 | cds-NP_013612.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:71285-72640:- | gene-YML097C_CBS6413 | rna-NM_001182457.1_CBS6413 | cds-NP_013612.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:72924-74279:- | gene-YML097C_CENPK1137D | rna-NM_001182457.1_CENPK1137D | cds-NP_013612.1_CENPK1137D | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:72562-73917:- | gene-YML097C_EthanolRed | rna-NM_001182457.1_EthanolRed | cds-NP_013612.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:72839-74194:- | gene-YML097C_FaliES1 | rna-NM_001182457.1_FaliES1 | cds-NP_013612.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000345.1:15988-17343:+ | gene-YML097C_JAY291 | rna-NM_001182457.1_JAY291 | cds-NP_013612.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:76755-78110:- | gene-YML097C_MUCL30387 | rna-NM_001182457.1_MUCL30387 | cds-NP_013612.1_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:79980-81335:- | gene-YML097C_MUCL30388 | rna-NM_001182457.1_MUCL30388 | cds-NP_013612.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:72072-73427:- | gene-YML097C_MUCL39482 | rna-NM_001182457.1_MUCL39482 | cds-NP_013612.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:76869-78224:- | gene-YML097C_MUCL42920 | rna-NM_001182457.1_MUCL42920 | cds-NP_013612.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:78289-79644:- | gene-YML097C_NCIM3186 | rna-NM_001182457.1_NCIM3186 | cds-NP_013612.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:72866-74221:- | gene-YML097C_NCYC1407 | rna-NM_001182457.1_NCYC1407 | cds-NP_013612.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:78299-79654:- | gene-YML097C_PE2H3 | rna-NM_001182457.1_PE2H3 | cds-NP_013612.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:78237-79592:- | gene-YML097C_PE2H4 | rna-NM_001182457.1_PE2H4 | cds-NP_013612.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:78335-79690:- | gene-YML097C_S288C | rna-NM_001182457.1_S288C | cds-NP_013612.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000054.1:70303-71658:- | gene-YML097C_SA1 | rna-NM_001182457.1_SA1 | cds-NP_013612.1_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:72135-73490:- | gene-YML097C_ThermosaccDry | rna-NM_001182457.1_ThermosaccDry | cds-NP_013612.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:76518-77873:- | gene-YML097C_VR1 | rna-NM_001182457.1_VR1 | cds-NP_013612.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:51636-52991:- | gene-YML097C_ZTW1 | rna-NM_001182457.1_ZTW1 | cds-NP_013612.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:82919-84277:- | gene-YML097C_Sparadoxus | rna-NM_001182457.1_Sparadoxus | cds-NP_013612.1_Sparadoxus | 87.7 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |